 Trophoblasts
"Trophoblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells lining the outside of the BLASTOCYST. After binding to the ENDOMETRIUM, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (PLACENTA).
| Descriptor ID |
D014327
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| MeSH Number(s) |
A11.382.992 A16.254.500.766 A16.710.802
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trophoblasts".
Below are MeSH descriptors whose meaning is more specific than "Trophoblasts".
This graph shows the total number of publications written about "Trophoblasts" by people in this website by year, and whether "Trophoblasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 3 | 2 | 5 | | 1999 | 2 | 1 | 3 | | 2000 | 3 | 1 | 4 | | 2001 | 0 | 1 | 1 | | 2002 | 4 | 2 | 6 | | 2003 | 3 | 1 | 4 | | 2004 | 3 | 0 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 3 | 0 | 3 | | 2009 | 4 | 1 | 5 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 2 | 3 | | 2012 | 3 | 2 | 5 | | 2013 | 1 | 2 | 3 | | 2014 | 4 | 4 | 8 | | 2015 | 5 | 1 | 6 | | 2016 | 3 | 1 | 4 | | 2017 | 4 | 0 | 4 | | 2018 | 1 | 4 | 5 | | 2019 | 5 | 2 | 7 | | 2020 | 2 | 4 | 6 | | 2021 | 2 | 1 | 3 | | 2022 | 4 | 1 | 5 | | 2023 | 3 | 1 | 4 | | 2024 | 1 | 2 | 3 | | 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Trophoblasts" by people in Profiles.
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Nunes LGA, Weingrill RB, Fredrick SBJ, Lorca R, Lee MJ, Atif SM, Chicco AJ, Rosario FJ, Urschitz J. Trophoblast-specific Deptor knockdown enhances trophoblast nutrient transport and fetal growth in mice. Acta Physiol (Oxf). 2025 Apr; 241(4):e70012.
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Kramer A, Vaughan OR, Barentsen K, Urschitz J, Powell TL, Jansson T, Rosario FJ. Lentivirus-Mediated Trophoblast-Specific Deptor Knockdown Increases Transplacental System A and System L Amino Acid Transport and Fetal Growth in Mice. Function (Oxf). 2025 Mar 24; 6(2).
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Dumolt JH, Rosario FJ, Barentsen K, Urschitz J, Powell TL, Jansson T. Trophoblast-specific overexpression of adiponectin receptor 2 causes fetal growth restriction in pregnant mice. FASEB J. 2024 Oct 15; 38(19):e70100.
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Lipka A, Paukszto L, Kennedy VC, Tanner AR, Majewska M, Anthony RV. The Impact of SLC2A8 RNA Interference on Glucose Uptake and the Transcriptome of Human Trophoblast Cells. Cells. 2024 02 24; 13(5).
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Karvas RM, Theunissen TW. Generation of 3D Trophoblast Organoids from Human Na?ve Pluripotent Stem Cells. Methods Mol Biol. 2024; 2767:85-103.
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Rosario FJ, Urschitz J, Powell TL, Brown TL, Jansson T. Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling. Clin Sci (Lond). 2023 11 15; 137(21):1651-1664.
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Kramer AC, Jansson T, Bale TL, Powell TL. Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism. Development. 2023 10 15; 150(20).
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Joshi N, Sahay A, Mane A, Sundrani D, Randhir K, Wagh G, Thornburg K, Powell T, Yajnik C, Joshi S. Altered expression of nutrient transporters in syncytiotrophoblast membranes in preeclampsia placentae. Placenta. 2023 08; 139:181-189.
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Zhou J, Tian Y, Qu Y, Williams M, Yuan Y, Karvas RM, Sheridan MA, Schulz LC, Ezashi T, Roberts MR, Schust DJ. The immune checkpoint molecule, VTCN1/B7-H4, guides differentiation and suppresses proinflammatory responses and MHC class I expression in an embryonic stem cell-derived model of human trophoblast. Front Endocrinol (Lausanne). 2023; 14:1069395.
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Karvas RM, David L, Theunissen TW. Accessing the human?trophoblast stem cell state from pluripotent and somatic cells. Cell Mol Life Sci. 2022 Nov 25; 79(12):604.
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