Interleukin-13
"Interleukin-13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine synthesized by T-LYMPHOCYTES that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-LYMPHOCYTES. It appears to play a role in regulating inflammatory and immune responses.
| Descriptor ID |
D018793
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| MeSH Number(s) |
D12.644.276.374.465.513 D12.776.467.374.465.513 D23.529.374.465.513
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-13".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-13".
This graph shows the total number of publications written about "Interleukin-13" by people in this website by year, and whether "Interleukin-13" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 | | 1999 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 1 | 3 | 4 | | 2006 | 3 | 1 | 4 | | 2007 | 3 | 1 | 4 | | 2008 | 1 | 4 | 5 | | 2009 | 0 | 4 | 4 | | 2010 | 1 | 3 | 4 | | 2011 | 3 | 2 | 5 | | 2012 | 1 | 2 | 3 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 3 | 4 | | 2015 | 2 | 4 | 6 | | 2016 | 0 | 1 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 6 | 2 | 8 | | 2019 | 0 | 3 | 3 | | 2020 | 3 | 6 | 9 | | 2021 | 1 | 3 | 4 | | 2022 | 1 | 3 | 4 | | 2023 | 2 | 3 | 5 | | 2024 | 1 | 0 | 1 | | 2025 | 2 | 1 | 3 | | 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interleukin-13" by people in Profiles.
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Hoang ON, Chan CE, Brenner JM, Leza-Rincon D, Jaramillo AM, Dolan B, Aziz AW, Cardenas RA, Cardenas GJ, Galvez ED, Hales JB, Nunez-Pena ES, Yang B, Powell RT, Vergara L, Karmouty-Quintana H, Magnusson JM, Hansson GC, Adachi R, Dickinson JD, Evans CM, Courson JA, Burns AR, Tuvim MJ, Dickey BF. Airway secretory cells contain both a perinuclear Golgi ribbon and dispersed Golgi satellites. Am J Respir Cell Mol Biol. 2026 Jul 01; 74(7):881-895.
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Graumuller F, Cervantes D, Chan TO, Schaunaman N, Villalba DR, Dickey BF, Walker JKL, Chu HW, Penn RB. Qualitative beta-2-adrenoceptor signaling in the regulation of human airway epithelia mucin and cytokine production. Respir Res. 2026 May 01; 27(1).
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Pivniouk V, Pivniouk O, Uhrlaub JL, Hahn S, Molzahn A, Kimura H, Numata M, Chu HW, Ledford JG, Kraft M, Nikolich J?, Vercelli D. IL-13 protects epithelial cells from SARS-CoV-2 infection by inhibiting ACE2-mediated virus binding and cell entry. Immunohorizons. 2025 11 24; 9(12).
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Paller AS, Soong W, Boguniewicz M, Geng B, Thyssen JP, Bennike N, Schneider S, Wollenberg A. Effect of tralokinumab on moderate-to-severe atopic dermatitis in patients with atopic comorbidities. Ann Allergy Asthma Immunol. 2025 10; 135(4):425-433.e4.
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Lee GY, Schaunaman N, Nouri HR, Kraft M, Chu HW. Comprehensive single-cell RNA-sequencing study of Tollip deficiency effect in IL-13-stimulated human airway epithelial cells. BMC Res Notes. 2025 Apr 23; 18(1):194.
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Szefler S, Corren J, Silverberg JI, Okragly A, Sun Z, Natalie CR, Zitnik R, Siu K, Blauvelt A. Lebrikizumab decreases type 2 inflammatory biomarker levels in patients with asthma: data from randomized phase 3 trials (LAVOLTA I and II). Immunotherapy. 2024; 16(20-22):1211-1216.
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Everman JL, Sajuthi SP, Liegeois MA, Jackson ND, Collet EH, Peters MC, Chioccioli M, Moore CM, Patel BB, Dyjack N, Powell R, Rios C, Montgomery MT, Eng C, Elhawary JR, Mak ACY, Hu D, Huntsman S, Salazar S, Feriani L, Fairbanks-Mahnke A, Zinnen GL, Michel CR, Gomez J, Zhang X, Medina V, Chu HW, Cicuta P, Gordon ED, Zeitlin P, Ortega VE, Reisdorph N, Dunican EM, Tang M, Elicker BM, Henry TS, Bleecker ER, Castro M, Erzurum SC, Israel E, Levy BD, Mauger DT, Meyers DA, Sumino K, Gierada DS, Hastie AT, Moore WC, Denlinger LC, Jarjour NN, Schiebler ML, Wenzel SE, Woodruff PG, Rodriguez-Santana J, Pearson CG, Burchard EG, Fahy JV, Seibold MA. A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma. Nat Commun. 2024 May 09; 15(1):3900.
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Corren J, Szefler SJ, Sher E, Korenblat P, Soong W, Hanania NA, Berman G, Brusselle G, Zitnik R, Natalie CR, Sun L, Siu K, Wu WS, Lio P, Armstrong AW. Lebrikizumab in Uncontrolled Asthma: Reanalysis in a Well-Defined Type 2 Population. J Allergy Clin Immunol Pract. 2024 05; 12(5):1215-1224.e3.
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Scott TE, Lewis CV, Zhu M, Wang C, Samuel CS, Drummond GR, Kemp-Harper BK. IL-4 and IL-13 induce equivalent expression of traditional M2 markers and modulation of reactive oxygen species in human macrophages. Sci Rep. 2023 11 10; 13(1):19589.
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Simpson EL, Guttman-Yassky E, Eichenfield LF, Boguniewicz M, Bieber T, Schneider S, Guana A, Silverberg JI. Tralokinumab therapy for moderate-to-severe atopic dermatitis: Clinical outcomes with targeted IL-13 inhibition. Allergy. 2023 11; 78(11):2875-2891.
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