 Peptaibols
"Peptaibols" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of peptides characterized by length of 1-2 dozen residues with a high proportion of them being non-proteinogenic, notably alpha-aminoisobutyric acid (Aib) and isovaline, and have a C-terminal amino alcohol and N terminal alkyl group. They are found in FUNGI and some are ANTI-INFECTIVE AGENTS. They form channels or pores in target organisms. The term is a contraction of peptide-Aib-alcohol.
| Descriptor ID |
D054848
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| MeSH Number(s) |
D12.644.504
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptaibols".
Below are MeSH descriptors whose meaning is more specific than "Peptaibols".
This graph shows the total number of publications written about "Peptaibols" by people in this website by year, and whether "Peptaibols" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptaibols" by people in Profiles.
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Figueroa M, Raja H, Falkinham JO, Adcock AF, Kroll DJ, Wani MC, Pearce CJ, Oberlies NH. Peptaibols, tetramic acid derivatives, isocoumarins, and sesquiterpenes from a Bionectria sp. (MSX 47401). J Nat Prod. 2013 Jun 28; 76(6):1007-15.
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Ayers S, Ehrmann BM, Adcock AF, Kroll DJ, Carcache de Blanco EJ, Shen Q, Swanson SM, Falkinham JO, Wani MC, Mitchell SM, Pearce CJ, Oberlies NH. Peptaibols from two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities. J Pept Sci. 2012 Aug; 18(8):500-10.
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