 Zinc Finger E-box Binding Homeobox 2
"Zinc Finger E-box Binding Homeobox 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.
| Descriptor ID |
D000074165
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| MeSH Number(s) |
D12.776.260.400.883 D12.776.260.703.700 D12.776.930.780.918
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| Concept/Terms |
Zinc Finger E-box Binding Homeobox 2- Zinc Finger E-box Binding Homeobox 2
- Zinc Finger E box Binding Homeobox 2
- Zinc Finger E-box Binding Homeobox 2 Protein
- Zinc Finger E box Binding Homeobox 2 Protein
- Zeb2 Transcription Factor
- Transcription Factor, Zeb2
- Smad-Interacting Protein 1
- Smad Interacting Protein 1
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Below are MeSH descriptors whose meaning is more general than "Zinc Finger E-box Binding Homeobox 2".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger E-box Binding Homeobox 2".
This graph shows the total number of publications written about "Zinc Finger E-box Binding Homeobox 2" by people in this website by year, and whether "Zinc Finger E-box Binding Homeobox 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Zinc Finger E-box Binding Homeobox 2" by people in Profiles.
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Wang CA, Drasin D, Pham C, Jedlicka P, Zaberezhnyy V, Guney M, Li H, Nemenoff R, Costello JC, Tan AC, Ford HL. Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression. Cancer Res. 2014 Dec 15; 74(24):7357-70.
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Howe EN, Cochrane DR, Richer JK. Targets of miR-200c mediate suppression of cell motility and anoikis resistance. Breast Cancer Res. 2011 Apr 18; 13(2):R45.
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Gemmill RM, Roche J, Potiron VA, Nasarre P, Mitas M, Coldren CD, Helfrich BA, Garrett-Mayer E, Bunn PA, Drabkin HA. ZEB1-responsive genes in non-small cell lung cancer. Cancer Lett. 2011 Jan 01; 300(1):66-78.
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