 Hypoxia-Inducible Factor 1
"Hypoxia-Inducible Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that plays a role in APOPTOSIS. It is composed of two subunits: ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR and HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT.
| Descriptor ID |
D051793
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| MeSH Number(s) |
D12.776.260.103.625 D12.776.930.125.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1" by people in this website by year, and whether "Hypoxia-Inducible Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 3 | 3 | | 2005 | 2 | 1 | 3 | | 2006 | 3 | 1 | 4 | | 2007 | 1 | 2 | 3 | | 2008 | 2 | 0 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 3 | 0 | 3 | | 2013 | 3 | 1 | 4 | | 2014 | 1 | 1 | 2 | | 2015 | 3 | 0 | 3 | | 2017 | 1 | 4 | 5 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1" by people in Profiles.
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Babapoor-Farrokhran S, Qin Y, Flores-Bellver M, Niu Y, Bhutto IA, Aparicio-Domingo S, Guo C, Rodrigues M, Domashevich T, Deshpande M, Megarity H, Chopde R, Eberhart CG, Canto-Soler V, Montaner S, Sodhi A. Pathologic vs. protective roles of hypoxia-inducible factor 1 in RPE and photoreceptors in wet vs. dry age-related macular degeneration. Proc Natl Acad Sci U S A. 2023 Dec 12; 120(50):e2302845120.
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Miglani M, Pasha Q, Gupta A, Priyadarshini A, Pati Pandey R, Vibhuti A. Seeding drug discovery: Telomeric tankyrase as a pharmacological target for the pathophysiology of high-altitude hypoxia. Drug Discov Today. 2021 11; 26(11):2774-2781.
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Hirsch K, Taglauer E, Seedorf G, Callahan C, Mandell E, White CW, Kourembanas S, Abman SH. Perinatal Hypoxia-Inducible Factor Stabilization Preserves Lung Alveolar and Vascular Growth in Experimental Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 10 15; 202(8):1146-1158.
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Colgan SP, Furuta GT, Taylor CT. Hypoxia and Innate Immunity: Keeping Up with the HIFsters. Annu Rev Immunol. 2020 04 26; 38:341-363.
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Baek JH, Buehler PW. Can molecular markers of oxygen homeostasis and the measurement of tissue oxygen be leveraged to optimize red blood cell transfusions? Curr Opin Hematol. 2019 11; 26(6):453-460.
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Urakami-Takebayashi Y, Kuroda Y, Murata T, Miyazaki M, Nagai J. Pioglitazone induces hypoxia-inducible factor 1 activation in human renal proximal tubular epithelial cell line HK-2. Biochem Biophys Res Commun. 2018 09 10; 503(3):1682-1688.
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Taylor CT, Colgan SP. Regulation of immunity and inflammation by hypoxia in immunological niches. Nat Rev Immunol. 2017 Dec; 17(12):774-785.
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Neudecker V, Colgan SP, Eltzschig HK. Novel therapeutic concepts for inflammatory bowel disease-from bench to bedside. J Mol Med (Berl). 2017 09; 95(9):899-903.
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Glover LE, Colgan SP. Epithelial Barrier Regulation by Hypoxia-Inducible Factor. Ann Am Thorac Soc. 2017 Sep; 14(Supplement_3):S233-S236.
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Colgan SP, Campbell EL. Oxygen metabolism and innate immune responses in the gut. J Appl Physiol (1985). 2017 Nov 01; 123(5):1321-1327.
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