 HIV Integrase Inhibitors
"HIV Integrase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inhibitors of HIV INTEGRASE, an enzyme required for integration of viral DNA into cellular DNA.
| Descriptor ID |
D019428
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| MeSH Number(s) |
D27.505.519.389.375.400 D27.505.954.122.388.077.088.314
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "HIV Integrase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "HIV Integrase Inhibitors".
This graph shows the total number of publications written about "HIV Integrase Inhibitors" by people in this website by year, and whether "HIV Integrase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 3 | 0 | 3 | | 2014 | 3 | 0 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 4 | 1 | 5 | | 2017 | 2 | 0 | 2 | | 2018 | 4 | 0 | 4 | | 2019 | 4 | 0 | 4 | | 2020 | 1 | 0 | 1 | | 2021 | 4 | 0 | 4 | | 2022 | 3 | 0 | 3 | | 2023 | 5 | 0 | 5 | | 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "HIV Integrase Inhibitors" by people in Profiles.
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Dinh T, Tber Z, Rey JS, Mengshetti S, Annamalai AS, Haney R, Briganti L, Amblard F, Fuchs JR, Cherepanov P, Kim K, Schinazi RF, Perilla JR, Kim B, Kvaratskhelia M. The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir. mBio. 2024 Nov 13; 15(11):e0046524.
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Kousari AE, Wilson MP, Hawkins KL, Bandali MM, Henao-Mart?nez AF, Gardner EM, Erlandson KM. Weight change with antiretroviral switch from integrase inhibitor or tenofovir alafenamide-based to Doravirine-Based regimens in people with HIV. HIV Res Clin Pract. 2024 12; 25(1):2339576.
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Erlandson KM, Mohaweche R, Morrow M, Mawhinney S, Khuu V, Boyd M, Balasubramanyam A, Melanson EL, Lake JE. Energy balance and body composition after switch between integrase strand transfer inhibitors and doravirine among people with HIV. J Antimicrob Chemother. 2024 01 03; 79(1):179-185.
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O'Halloran JA, Parra-Rodriguez L, Goss CW, Agarwal M, Cooley S, Wu K, Westerhaus E, Presti R, Ances BM, Tassiopoulos K, Erlandson KM. Impact of Integrase Strand Transfer Inhibitors on Cognition in the HAILO Cohort. J Acquir Immune Defic Syndr. 2023 12 15; 94(5):437-444.
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Wu K, Koethe J, Hulgan T, Brown T, Bares SH, Tassiopoulos K, Lake JE, Leonard M, Samuels DC, Erlandson K, Haas DW. Pharmacogenetics of weight gain following switch from efavirenz- to integrase inhibitor-containing regimens. Pharmacogenet Genomics. 2024 Feb 01; 34(2):25-32.
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Li M, Oliveira Passos D, Shan Z, Smith SJ, Sun Q, Biswas A, Choudhuri I, Strutzenberg TS, Haldane A, Deng N, Li Z, Zhao XZ, Briganti L, Kvaratskhelia M, Burke TR, Levy RM, Hughes SH, Craigie R, Lyumkis D. Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv. 2023 07 21; 9(29):eadg5953.
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Smith C, Fought AJ, Sung JF, McKinney JR, Metz TD, Fetters KB, Lazarus S, Capraro S, Barr E, Glenny C, Buehler J, Weinberg A. Congenital malformations and preeclampsia associated with integrase inhibitor use in pregnancy: A single-center analysis. PLoS One. 2023; 18(6):e0276473.
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Singer MR, Dinh T, Levintov L, Annamalai AS, Rey JS, Briganti L, Cook NJ, Pye VE, Taylor IA, Kim K, Engelman AN, Kim B, Perilla JR, Kvaratskhelia M, Cherepanov P. The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio. 2023 02 28; 14(1):e0356022.
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Guaraldi G, Milic J, Bacchi E, Carli F, Menozzi M, Franconi I, Raimondi A, Ciusa G, Masi V, Belli M, Guaraldi S, Aprile E, Mancini M, Mussini C, Lake JE, Erlandson KM. Contribution of integrase inhibitor use, body mass index, physical activity and caloric intake to weight gain in people living with HIV. HIV Res Clin Pract. 2022 11 22; 24(1):1-6.
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Singh PK, Li W, Bedwell GJ, Fadel HJ, Poeschla EM, Engelman AN. Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors. Viruses. 2022 08 26; 14(9).
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