 NIMA-Related Kinases
"NIMA-Related Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly-conserved family of protein serine-threonine kinases that regulate the CELL CYCLE; MITOSIS; and the response to DNA DAMAGE. They are also involved in the assembly and function of microtubule-based structures such as CILIA and CENTRIOLES.
| Descriptor ID |
D000072379
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| MeSH Number(s) |
D08.811.913.696.620.682.700.581 D12.776.167.457
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| Concept/Terms |
NIMA-Related Kinases- NIMA-Related Kinases
- Kinases, NIMA-Related
- NIMA Related Kinases
- NIMA Protein Kinase
- NEK Family Kinases
- Kinases, NEK Family
- NIMA Family Kinases
- Kinases, NIMA Family
- NEK Kinases
- Kinases, NEK
- NIMA-Related Protein Kinase
- NIMA Related Protein Kinase
- Never-in-Mitosis A Kinases
- Kinases, Never-in-Mitosis A
- Never in Mitosis A Kinases
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Below are MeSH descriptors whose meaning is more general than "NIMA-Related Kinases".
Below are MeSH descriptors whose meaning is more specific than "NIMA-Related Kinases".
This graph shows the total number of publications written about "NIMA-Related Kinases" by people in this website by year, and whether "NIMA-Related Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "NIMA-Related Kinases" by people in Profiles.
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O'Regan L, Barone G, Adib R, Woo CG, Jeong HJ, Richardson EL, Richards MW, Muller PAJ, Collis SJ, Fennell DA, Choi J, Bayliss R, Fry AM. EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7. J Cell Sci. 2020 05 11; 133(9).
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Kiseljak-Vassiliades K, Zhang Y, Kar A, Razzaghi R, Xu M, Gowan K, Raeburn CD, Albuja-Cruz M, Jones KL, Somerset H, Fishbein L, Leong S, Wierman ME. Elucidating the Role of the Maternal Embryonic Leucine Zipper Kinase in Adrenocortical Carcinoma. Endocrinology. 2018 07 01; 159(7):2532-2544.
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Coxon CR, Wong C, Bayliss R, Boxall K, Carr KH, Fry AM, Hardcastle IR, Matheson CJ, Newell DR, Sivaprakasam M, Thomas H, Turner D, Yeoh S, Wang LZ, Griffin RJ, Golding BT, Cano C. Structure-guided design of purine-based probes for selective Nek2 inhibition. Oncotarget. 2017 Mar 21; 8(12):19089-19124.
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Lebraud H, Coxon CR, Archard VS, Bawn CM, Carbain B, Matheson CJ, Turner DM, Cano C, Griffin RJ, Hardcastle IR, Baisch U, Harrington RW, Golding BT. Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org Biomol Chem. 2014 Jan 07; 12(1):141-8.
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Kohler ME, Johnson BD, Palen K, Chen QR, Khan J, Orentas RJ. Tumor antigen analysis in neuroblastoma by serological interrogation of bioinformatic data. Cancer Sci. 2010 Nov; 101(11):2316-24.
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Du J, Cai X, Yao J, Ding X, Wu Q, Pei S, Jiang K, Zhang Y, Wang W, Shi Y, Lai Y, Shen J, Teng M, Huang H, Fei Q, Reddy ES, Zhu J, Jin C, Yao X. The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability. Oncogene. 2008 Jul 03; 27(29):4107-14.
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Bahmanyar S, Kaplan DD, Deluca JG, Giddings TH, O'Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI. beta-Catenin is a Nek2 substrate involved in centrosome separation. Genes Dev. 2008 Jan 01; 22(1):91-105.
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