Zyxin
"Zyxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half.
| Descriptor ID |
D060589
|
| MeSH Number(s) |
D12.776.220.995 D12.776.512.500 D12.776.744.962
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Zyxin".
Below are MeSH descriptors whose meaning is more specific than "Zyxin".
This graph shows the total number of publications written about "Zyxin" by people in this website by year, and whether "Zyxin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Zyxin" by people in Profiles.
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Mise N, Savai R, Yu H, Schwarz J, Kaminski N, Eickelberg O. Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin a5?1. J Biol Chem. 2012 Sep 07; 287(37):31393-405.
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Franco SJ, Rodgers MA, Perrin BJ, Han J, Bennin DA, Critchley DR, Huttenlocher A. Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol. 2004 Oct; 6(10):977-83.