 Receptor-Interacting Protein Serine-Threonine Kinases
"Receptor-Interacting Protein Serine-Threonine Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
| Descriptor ID |
D053422
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| MeSH Number(s) |
D08.811.913.696.620.682.700.801 D12.644.360.024.285.400 D12.644.360.024.500.186 D12.644.360.075.421.400 D12.776.157.057.018.400 D12.776.157.057.500.186 D12.776.476.024.320.662 D12.776.476.024.500.186 D12.776.476.075.421.400
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| Concept/Terms |
Receptor-Interacting Protein Serine-Threonine Kinases- Receptor-Interacting Protein Serine-Threonine Kinases
- Receptor Interacting Protein Serine Threonine Kinases
- RIP Serine-Threonine Kinases
- Kinases, RIP Serine-Threonine
- RIP Serine Threonine Kinases
- Serine-Threonine Kinases, RIP
Receptor-Interacting Protein Serine-Threonine Kinase 1- Receptor-Interacting Protein Serine-Threonine Kinase 1
- Receptor Interacting Protein Serine Threonine Kinase 1
- Receptor Interacting Protein RIP
- RIP Serine-Threonine Kinase
- Kinase, RIP Serine-Threonine
- RIP Serine Threonine Kinase
- Serine-Threonine Kinase, RIP
- RIP (Receptor Interacting Protein)
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Below are MeSH descriptors whose meaning is more general than "Receptor-Interacting Protein Serine-Threonine Kinases".
Below are MeSH descriptors whose meaning is more specific than "Receptor-Interacting Protein Serine-Threonine Kinases".
This graph shows the total number of publications written about "Receptor-Interacting Protein Serine-Threonine Kinases" by people in this website by year, and whether "Receptor-Interacting Protein Serine-Threonine Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 2 | 3 | | 2018 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor-Interacting Protein Serine-Threonine Kinases" by people in Profiles.
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Kandhari K, Mishra JPN, Agarwal R, Singh RP. Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells. Toxicol Appl Pharmacol. 2023 03 01; 462:116409.
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Beno SM, Riegler AN, Gilley RP, Brissac T, Wang Y, Kruckow KL, Jadapalli JK, Wright GM, Shenoy AT, Stoner SN, Restrepo MI, Deshane JS, Halade GV, Gonz?lez-Juarbe N, Orihuela CJ. Inhibition of Necroptosis to Prevent Long-term Cardiac Damage During Pneumococcal Pneumonia and Invasive Disease. J Infect Dis. 2020 11 09; 222(11):1882-1893.
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Mishra SK, Stephenson DJ, Chalfant CE, Brown RE. Upregulation of human glycolipid transfer protein (GLTP) induces necroptosis in colon carcinoma cells. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 02; 1864(2):158-167.
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Pajuelo D, Gonzalez-Juarbe N, Tak U, Sun J, Orihuela CJ, Niederweis M. NAD+ Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis. Cell Rep. 2018 07 10; 24(2):429-440.
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Goodall ML, Cramer SD, Thorburn A. Autophagy RIPs into cell death. Cell Cycle. 2016 11 16; 15(22):3014-3015.
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Roychowdhury S, McCullough RL, Sanz-Garcia C, Saikia P, Alkhouri N, Matloob A, Pollard KA, McMullen MR, Croniger CM, Nagy LE. Receptor interacting protein 3 protects mice from high-fat diet-induced liver?injury. Hepatology. 2016 11; 64(5):1518-1533.
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Goodall ML, Fitzwalter BE, Zahedi S, Wu M, Rodriguez D, Mulcahy-Levy JM, Green DR, Morgan M, Cramer SD, Thorburn A. The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis. Dev Cell. 2016 May 23; 37(4):337-349.
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Ozkok A, Ravichandran K, Wang Q, Ljubanovic D, Edelstein CL. NF-?B transcriptional inhibition ameliorates cisplatin-induced acute kidney injury (AKI). Toxicol Lett. 2016 Jan 05; 240(1):105-13.
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Fitzwalter BE, Thorburn A. Recent insights into cell death and autophagy. FEBS J. 2015 Nov; 282(22):4279-88.
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Koo GB, Morgan MJ, Lee DG, Kim WJ, Yoon JH, Koo JS, Kim SI, Kim SJ, Son MK, Hong SS, Levy JM, Pollyea DA, Jordan CT, Yan P, Frankhouser D, Nicolet D, Maharry K, Marcucci G, Choi KS, Cho H, Thorburn A, Kim YS. Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics. Cell Res. 2015 Jun; 25(6):707-25.
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