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Bruce A. Molitoris

TitleAffiliate
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

    Collapse Research 
    Collapse research activities and funding
    R56DK125960     (CARROLL, THOMAS JOSEPH)Sep 15, 2020 - Sep 14, 2021
    NIH
    Application of Progenitor Niche Signals to Ex Vivo Nephrogenesis
    Role: Co-Principal Investigator
    I01BX001137     (BACALLAO, ROBERT L)Oct 1, 2011 - Mar 31, 2021
    NIH
    Reducing Nephrotoxicity while enabling read through of missense stop codons by Gentamicin congeners
    Role: Co-Principal Investigator
    R01DK091623     (MOLITORIS, BRUCE A)Sep 30, 2011 - May 31, 2022
    NIH
    Proximal Tubule Albumin Transport in Disease States.
    Role: Principal Investigator
    R44DK093274     (MEIER, DANIEL)Sep 20, 2011 - Jul 31, 2018
    NIH
    Clinical and Non-Clinical Evaluations of repeat administrations of the FAST PV and mGFR Technology
    Role: Co-Principal Investigator
    R01DK088934     (ATKINSON, SIMON J.)Aug 11, 2011 - Apr 30, 2016
    NIH
    Utilizing siRNA to Minimize Nephrotoxic Injury
    Role: Co-Principal Investigator
    R42DK079477     (MOLITORIS, BRUCE A)Jun 10, 2008 - May 31, 2011
    NIH
    Non-Invasive Optical Determination of GFR
    Role: Principal Investigator
    R41DK079477     (MOLITORIS, BRUCE A)Jun 10, 2008 - Jun 9, 2009
    NIH
    Non-Invasive Optical Determination of GFR
    Role: Principal Investigator
    P30DK079312     (DAGHER, PIERRE C)Aug 3, 2007 - Jun 30, 2022
    NIH
    Center for Advanced Renal Microscopic Analysis
    Role: Co-Principal Investigator
    R42DK076478     (DUNN, KENNETH W)Jul 1, 2006 - Jul 31, 2014
    NIH
    Kidney Multiphoton Analysis of Therapeutic Agents
    Role: Co-Principal Investigator
    R01DK069408     (MOLITORIS, BRUCE A)Aug 1, 2005 - Jul 31, 2010
    NIH
    Ischemia-induced Actin Cytoskeletal Alterations
    Role: Principal Investigator
    P50DK061594     (MOLITORIS, BRUCE A)Jun 1, 2002 - May 31, 2007
    NIH
    Center for Advanced Renal Microscopic Analysis
    Role: Principal Investigator
    P01DK053465     (MOLITORIS, BRUCE A)Mar 1, 2000 - Jan 31, 2006
    NIH
    ACTIN DYSREGULATION IN ISCHEMIA: MECHANISMS AND EFFECTS
    Role: Principal Investigator
    R01DK055527     (MOLITORIS, BRUCE A)Sep 18, 1998 - Aug 31, 2004
    NIH
    RAB5 AND PI-3-KINASE AND GENTAMICIN TOXICITY
    Role: Principal Investigator
    R01DK041126     (MOLITORIS, BRUCE A)May 1, 1990 - Mar 31, 2003
    NIH
    ISCHEMIA-INDUCED LOSS OF EPITHELIAL POLARITY
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Molitoris BA, Dunn KW, Sandoval RM. Proximal tubule role in albumin homeostasis: controversy, species differences, and the contributions of intravital microscopy. Kidney Int. 2023 12; 104(6):1065-1069. PMID: 37981429.
      View in: PubMed
    2. van Till JWO, Nojima H, Kameoka C, Hayashi C, Sakatani T, Washburn TB, Molitoris BA, Shaw AD, Engelman DT, Kellum JA. The Effects of Peroxisome Proliferator-Activated Receptor-Delta Modulator ASP1128 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery. Kidney Int Rep. 2023 Jul; 8(7):1407-1416. PMID: 37441472.
      View in: PubMed
    3. Molitoris BA, Wagner MC. Is Albumin Toxic to the Kidney?: It Depends. Clin J Am Soc Nephrol. 2023 09 01; 18(9):1222-1224. PMID: 36942999.
      View in: PubMed
    4. Wagner MC, Sandoval RM, Yadav SPS, Campos SB, Rhodes GJ, Phillips CL, Molitoris BA. Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. Kidney360. 2023 05 01; 4(5):591-605. PMID: 36848531.
      View in: PubMed
    5. Bryniarski MA, Sandoval RM, Ruszaj DM, Fraser-McArthur J, Yee BM, Yacoub R, Chaves LD, Campos-Bilderback SB, Molitoris BA, Morris ME. Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide. Mol Pharm. 2023 02 06; 20(2):987-996. PMID: 36626167.
      View in: PubMed
    6. Datta-Mannan A, Molitoris BA, Feng Y, Martinez MM, Sandoval RM, Brown RM, Merkel D, Croy JE, Dunn KW. Intravital Microscopy Reveals Unforeseen Biodistribution Within the Liver and Kidney Mechanistically Connected to the Clearance of a Bifunctional Antibody. Drug Metab Dispos. 2023 03; 51(3):403-412. PMID: 36460476.
      View in: PubMed
    7. Yu A, Zhao J, Peng W, Yadav SPS, Molitoris BA, Wagner MC, Mechref Y. Proteomics profiling of kidney brush border membrane from rats using LC-MS/MS analysis. Proteomics Clin Appl. 2023 03; 17(2):e2200063. PMID: 36189891.
      View in: PubMed
    8. Yadav SPS, Yu A, Zhao J, Singh J, Kakkar S, Chakraborty S, Mechref Y, Molitoris B, Wagner MC. Glycosylation of a key cubilin Asn residue results in reduced binding to albumin. J Biol Chem. 2022 10; 298(10):102371. PMID: 35970386.
      View in: PubMed
    9. Rosin DL, Hall JP, Zheng S, Huang L, Campos-Bilderback S, Sandoval R, Bree A, Beaumont K, Miller E, Larsen J, Hariri G, Kaila N, Encarnacion IM, Gale JD, van Elsas A, Molitoris BA, Okusa MD. Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors. Front Med (Lausanne). 2022; 9:931293. PMID: 35966871.
      View in: PubMed
    10. Molitoris BA. Low-Flow Acute Kidney Injury: The Pathophysiology of Prerenal Azotemia, Abdominal Compartment Syndrome, and Obstructive Uropathy. Clin J Am Soc Nephrol. 2022 07; 17(7):1039-1049. PMID: 35584927.
      View in: PubMed
    11. Swolinsky JS, Molitoris BA, Schmidt-Ott KM. Response to Letter to the editor regarding 'Discordance between estimated and measured changes in plasma volume among patients with acute heart failure'. ESC Heart Fail. 2022 08; 9(4):2762-2763. PMID: 35561098.
      View in: PubMed
    12. Dunn KW, Hall AM, Molitoris BA. Editorial: Proceedings of the 2021 Indiana O'Brien Center Microscopy Workshop. Front Physiol. 2022; 13:891526. PMID: 35586716.
      View in: PubMed
    13. Molitoris BA, Sandoval RM, Yadav SPS, Wagner MC. Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiol Rev. 2022 10 01; 102(4):1625-1667. PMID: 35378997.
      View in: PubMed
    14. Molitoris BA, Sandoval RM, Wagner MC. Intravital Multiphoton Microscopy as a Tool for Studying Renal Physiology, Pathophysiology and Therapeutics. Front Physiol. 2022; 13:827280. PMID: 35399274.
      View in: PubMed
    15. Wagner MC, Sandoval RM, Campos-Bilderback SB, Molitoris BA. Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes. J Vis Exp. 2022 03 04; (181). PMID: 35311826.
      View in: PubMed
    16. Swolinsky JS, Tuvshinbat E, Leistner DM, Edelmann F, Knebel F, Nerger NP, Lemke C, Roehle R, Haase M, Costanzo MR, Rauch G, Mitrovic V, Gasanin E, Meier D, McCullough PA, Eckardt KU, Molitoris BA, Schmidt-Ott KM. Discordance between estimated and measured changes in plasma volume among patients with acute heart failure. ESC Heart Fail. 2022 02; 9(1):66-76. PMID: 34881523.
      View in: PubMed
    17. Yu A, Zhao J, Yadav SPS, Molitoris BA, Wagner MC, Mechref Y. Changes in the Expression of Renal Brush Border Membrane N-Glycome in Model Rats with Chronic Kidney Diseases. Biomolecules. 2021 11 11; 11(11). PMID: 34827675.
      View in: PubMed
    18. Yu A, Zhao J, Zhong J, Wang J, Yadav SPS, Molitoris BA, Wagner MC, Mechref Y. Altered O-glycomes of Renal Brush-Border Membrane in Model Rats with Chronic Kidney Diseases. Biomolecules. 2021 10 21; 11(11). PMID: 34827558.
      View in: PubMed
    19. Thielmann M, Corteville D, Szabo G, Swaminathan M, Lamy A, Lehner LJ, Brown CD, Noiseux N, Atta MG, Squiers EC, Erlich S, Rothenstein D, Molitoris B, Mazer CD. Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study. Circulation. 2021 10 05; 144(14):1133-1144. PMID: 34474590.
      View in: PubMed
    20. Swolinsky JS, Nerger NP, Leistner DM, Edelmann F, Knebel F, Tuvshinbat E, Lemke C, Roehle R, Haase M, Costanzo MR, Rauch G, Mitrovic V, Gasanin E, Meier D, McCullough PA, Eckardt KU, Molitoris BA, Schmidt-Ott KM. Serum creatinine and cystatin C-based estimates of glomerular filtration rate are misleading in acute heart failure. ESC Heart Fail. 2021 08; 8(4):3070-3081. PMID: 33955699.
      View in: PubMed
    21. Dunn KW, Molitoris BA, Dagher PC. The Indiana O'Brien Center for Advanced Renal Microscopic Analysis. Am J Physiol Renal Physiol. 2021 05 01; 320(5):F671-F682. PMID: 33682441.
      View in: PubMed
    22. Yadav SPS, Sandoval RM, Zhao J, Huang Y, Wang E, Kumar S, Campos-Bilderback SB, Rhodes G, Mechref Y, Molitoris BA, Wagner MC. Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol. 2021 01 01; 320(1):F114-F129. PMID: 33283642.
      View in: PubMed
    23. Schneider AG, Molitoris BA. Real-time glomerular filtration rate: improving sensitivity, accuracy and prognostic value in acute kidney injury. Curr Opin Crit Care. 2020 12; 26(6):549-555. PMID: 33002974.
      View in: PubMed
    24. Otterpohl KL, Busselman BW, Ratnayake I, Hart RG, Hart KR, Evans CM, Phillips CL, Beach JR, Ahrenkiel P, Molitoris BA, Surendran K, Chandrasekar I. Conditional Myh9 and Myh10 inactivation in adult mouse renal epithelium results in progressive kidney disease. JCI Insight. 2020 11 05; 5(21). PMID: 33001861.
      View in: PubMed
    25. Liu XF, Wei J, Zhou Q, Molitoris BA, Sandoval R, Kobayashi H, Okada R, Nagaya T, Karim B, Butcher D, Pastan I. Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6086-6091. PMID: 32123080.
      View in: PubMed
    26. Molitoris BA. DNA damage response protects against progressive kidney disease. J Clin Invest. 2019 11 01; 129(11):4574-4575. PMID: 31589167.
      View in: PubMed
    27. Uchida M, Maier B, Waghwani HK, Selivanovitch E, Pay SL, Avera J, Yun E, Sandoval RM, Molitoris BA, Zollman A, Douglas T, Hato T. The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration. J Clin Invest. 2019 09 03; 129(9):3941-3951. PMID: 31424427.
      View in: PubMed
    28. Bayliss GP, Cobb J, Decker B, Hellman R, Vasavada N, Mackelaite L, Shadur C, Ilori T, Ibrahim T, Leight K, Hsiao LL, Molitoris BA, Okusa MD, Parker MG. Kidney Mentoring and Assessment Program for Students: a guide for engaging medical students in nephrology. Clin Kidney J. 2019 Dec; 12(6):761-766. PMID: 31807288.
      View in: PubMed
    29. Ferrell N, Sandoval RM, Molitoris BA, Brakeman P, Roy S, Fissell WH. Application of physiological shear stress to renal tubular epithelial cells. Methods Cell Biol. 2019; 153:43-67. PMID: 31395384.
      View in: PubMed
    30. Molitoris BA. Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury. Mayo Clin Proc. 2019 05; 94(5):748-750. PMID: 31054601.
      View in: PubMed
    31. Molitoris BA, George AG, Murray PT, Meier D, Reilly ES, Barreto E, Sandoval RM, Rizk DV, Shaw AD, Peacock WF. A Novel Fluorescent Clinical Method to Rapidly Quantify Plasma Volume. Cardiorenal Med. 2019; 9(3):168-179. PMID: 30844821.
      View in: PubMed
    32. Sandoval RM, Molitoris BA, Palygin O. Fluorescent Imaging and Microscopy for Dynamic Processes in Rats. Methods Mol Biol. 2019; 2018:151-175. PMID: 31228156.
      View in: PubMed
    33. Pickkers P, Mehta RL, Murray PT, Joannidis M, Molitoris BA, Kellum JA, Bachler M, Hoste EAJ, Hoiting O, Krell K, Ostermann M, Rozendaal W, Valkonen M, Brealey D, Beishuizen A, Meziani F, Murugan R, de Geus H, Payen D, van den Berg E, Arend J. Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial. JAMA. 2018 11 20; 320(19):1998-2009. PMID: 30357272.
      View in: PubMed
    34. Schulz A, Chuquimia OD, Antypas H, Steiner SE, Sandoval RM, Tanner GA, Molitoris BA, Richter-Dahlfors A, Melican K. Protective vascular coagulation in response to bacterial infection of the kidney is regulated by bacterial lipid A and host CD147. Pathog Dis. 2018 11 01; 76(8). PMID: 30476069.
      View in: PubMed
    35. Rizk DV, Meier D, Sandoval RM, Chacana T, Reilly ES, Seegmiller JC, DeNoia E, Strickland JS, Muldoon J, Molitoris BA. A Novel Method for Rapid Bedside Measurement of GFR. J Am Soc Nephrol. 2018 06; 29(6):1609-1613. PMID: 29748326.
      View in: PubMed
    36. Kolb AL, Corridon PR, Zhang S, Xu W, Witzmann FA, Collett JA, Rhodes GJ, Winfree S, Bready D, Pfeffenberger ZJ, Pomerantz JM, Hato T, Nagami GT, Molitoris BA, Basile DP, Atkinson SJ, Bacallao RL. Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection. J Am Soc Nephrol. 2018 04; 29(4):1154-1164. PMID: 29371417.
      View in: PubMed
    37. Sandoval RM, Molitoris BA. Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology. Methods. 2017 09 01; 128:20-32. PMID: 28733090.
      View in: PubMed
    38. Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O. Intravital imaging of the kidney in a rat model of salt-sensitive hypertension. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F163-F173. PMID: 28404591.
      View in: PubMed
    39. Hato T, Winfree S, Day R, Sandoval RM, Molitoris BA, Yoder MC, Wiggins RC, Zheng Y, Dunn KW, Dagher PC. Two-Photon Intravital Fluorescence Lifetime Imaging of the Kidney Reveals Cell-Type Specific Metabolic Signatures. J Am Soc Nephrol. 2017 Aug; 28(8):2420-2430. PMID: 28250053.
      View in: PubMed
    40. Molitoris BA. Rethinking CKD Evaluation: Should We Be Quantifying Basal or Stimulated GFR to Maximize Precision and Sensitivity? Am J Kidney Dis. 2017 May; 69(5):675-683. PMID: 28223001.
      View in: PubMed
    41. Collett JA, Corridon PR, Mehrotra P, Kolb AL, Rhodes GJ, Miller CA, Molitoris BA, Pennington JG, Sandoval RM, Atkinson SJ, Campos-Bilderback SB, Basile DP, Bacallao RL. Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys. J Am Soc Nephrol. 2017 Jul; 28(7):2081-2092. PMID: 28122967.
      View in: PubMed
    42. McCurley A, Alimperti S, Campos-Bilderback SB, Sandoval RM, Calvino JE, Reynolds TL, Quigley C, Mugford JW, Polacheck WJ, Gomez IG, Dovey J, Marsh G, Huang A, Qian F, Weinreb PH, Dolinski BM, Moore S, Duffield JS, Chen CS, Molitoris BA, Violette SM, Crackower MA. Inhibition of av?5 Integrin Attenuates Vascular Permeability and Protects against Renal Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2017 Jun; 28(6):1741-1752. PMID: 28062569.
      View in: PubMed
    43. McCullough PA, Bennett-Guerrero E, Chawla LS, Beaver T, Mehta RL, Molitoris BA, Eldred A, Ball G, Lee HJ, Houser MT, Khan S. ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial. J Am Heart Assoc. 2016 08 20; 5(8). PMID: 27543797.
      View in: PubMed
    44. Wagner MC, Myslinski J, Pratap S, Flores B, Rhodes G, Campos-Bilderback SB, Sandoval RM, Kumar S, Patel M, Molitoris BA. Mechanism of increased clearance of glycated albumin by proximal tubule cells. Am J Physiol Renal Physiol. 2016 05 01; 310(10):F1089-102. PMID: 26887834.
      View in: PubMed
    45. Molitoris BA, Reilly ES. Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success. Semin Nephrol. 2016 Jan; 36(1):31-41. PMID: 27085733.
      View in: PubMed
    46. Matejovic M, Ince C, Chawla LS, Blantz R, Molitoris BA, Rosner MH, Okusa MD, Kellum JA, Ronco C. Renal Hemodynamics in AKI: In Search of New Treatment Targets. J Am Soc Nephrol. 2016 Jan; 27(1):49-58. PMID: 26510884.
      View in: PubMed
    47. Floege J, Mak RH, Molitoris BA, Remuzzi G, Ronco P. Nephrology research--the past, present and future. Nat Rev Nephrol. 2015 11; 11(11):677-87. PMID: 26416499.
      View in: PubMed
    48. Wagner MC, Campos-Bilderback SB, Chowdhury M, Flores B, Lai X, Myslinski J, Pandit S, Sandoval RM, Wean SE, Wei Y, Satlin LM, Wiggins RC, Witzmann FA, Molitoris BA. Proximal Tubules Have the Capacity to Regulate Uptake of Albumin. J Am Soc Nephrol. 2016 Feb; 27(2):482-94. PMID: 26054544.
      View in: PubMed
    49. Mitchell AM, Molitoris BA, Teague SD. Contrast Material-induced Nephropathy: Causation Quandaries. Radiology. 2015 Jun; 275(3):928-9. PMID: 25997136.
      View in: PubMed
    50. de Zeeuw D, Anzalone DA, Cain VA, Cressman MD, Heerspink HJ, Molitoris BA, Monyak JT, Parving HH, Remuzzi G, Sowers JR, Vidt DG. Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial. Lancet Diabetes Endocrinol. 2015 Mar; 3(3):181-90. PMID: 25660356.
      View in: PubMed
    51. Ferrell N, Sandoval RM, Bian A, Campos-Bilderback SB, Molitoris BA, Fissell WH. Shear stress is normalized in glomerular capillaries following ? nephrectomy. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F588-93. PMID: 25587117.
      View in: PubMed
    52. Verma SK, Molitoris BA. Renal endothelial injury and microvascular dysfunction in acute kidney injury. Semin Nephrol. 2015 Jan; 35(1):96-107. PMID: 25795503.
      View in: PubMed
    53. Molitoris BA. Urinary Biomarkers: Alone Are They Enough? J Am Soc Nephrol. 2015 Jul; 26(7):1485-8. PMID: 25535304.
      View in: PubMed
    54. Hall AM, Molitoris BA. Dynamic multiphoton microscopy: focusing light on acute kidney injury. Physiology (Bethesda). 2014 Sep; 29(5):334-42. PMID: 25180263.
      View in: PubMed
    55. Molitoris BA. Therapeutic translation in acute kidney injury: the epithelial/endothelial axis. J Clin Invest. 2014 Jun; 124(6):2355-63. PMID: 24892710.
      View in: PubMed
    56. Carrisoza-Gaytan R, Liu Y, Flores D, Else C, Lee HG, Rhodes G, Sandoval RM, Kleyman TR, Lee FY, Molitoris B, Satlin LM, Rohatgi R. Effects of biomechanical forces on signaling in the cortical collecting duct (CCD). Am J Physiol Renal Physiol. 2014 Jul 15; 307(2):F195-204. PMID: 24872319.
      View in: PubMed
    57. Sandoval RM, Molitoris BA. Letter to the editor: "Quantifying albumin permeability with multiphoton microscopy: why the difference?". Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1098-100. PMID: 24785957.
      View in: PubMed
    58. Molitoris BA. ASN Presidential Address 2013: innovation and individualization--the path forward for nephrology. J Am Soc Nephrol. 2014 May; 25(5):893-7. PMID: 24676637.
      View in: PubMed
    59. Sandoval RM, Wang E, Molitoris BA. Finding the bottom and using it: Offsets and sensitivity in the detection of low intensity values in vivo with 2-photon microscopy. Intravital. 2014 Mar 01; 2(1). PMID: 25313346.
      View in: PubMed
    60. Dickson LE, Wagner MC, Sandoval RM, Molitoris BA. The proximal tubule and albuminuria: really! J Am Soc Nephrol. 2014 Mar; 25(3):443-53. PMID: 24408874.
      View in: PubMed
    61. Molitoris BA. Using 2-photon microscopy to understand albuminuria. Trans Am Clin Climatol Assoc. 2014; 125:343-56; discussion 356-7. PMID: 25125750.
      View in: PubMed
    62. Molitoris BA. Screening: Screening for kidney disease--a lost opportunity. Nat Rev Nephrol. 2014 Jan; 10(1):6-8. PMID: 24296624.
      View in: PubMed
    63. Molitoris BA. Measuring glomerular filtration rate in the intensive care unit: no substitutes please. Crit Care. 2013 Sep 04; 17(5):181. PMID: 24004539.
      View in: PubMed
    64. Molitoris BA. AKI is around the world but public recognition is lacking. Clin J Am Soc Nephrol. 2013 Sep; 8(9):1467-8. PMID: 23949233.
      View in: PubMed
    65. Bonventre JV, Basile D, Liu KD, McKay D, Molitoris BA, Nath KA, Nickolas TL, Okusa MD, Palevsky PM, Schnellmann R, Rys-Sikora K, Kimmel PL, Star RA. AKI: a path forward. Clin J Am Soc Nephrol. 2013 Sep; 8(9):1606-8. PMID: 23868899.
      View in: PubMed
    66. Parker MG, Pivert KA, Ibrahim T, Molitoris BA. Recruiting the next generation of nephrologists. Adv Chronic Kidney Dis. 2013 Jul; 20(4):326-35. PMID: 23809285.
      View in: PubMed
    67. Sandoval RM, Molitoris BA. Quantifying glomerular permeability of fluorescent macromolecules using 2-photon microscopy in Munich Wistar rats. J Vis Exp. 2013 Apr 17; (74). PMID: 23628966.
      View in: PubMed
    68. Molitoris BA. Measuring glomerular filtration rate in acute kidney injury: yes, but not yet. Crit Care. 2012 Sep 24; 16(5):158. PMID: 23014799.
      View in: PubMed
    69. Hall AM, Rhodes GJ, Sandoval RM, Corridon PR, Molitoris BA. In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury. Kidney Int. 2013 Jan; 83(1):72-83. PMID: 22992467.
      View in: PubMed
    70. Thompson JD, Kornbrust DJ, Foy JW, Solano EC, Schneider DJ, Feinstein E, Molitoris BA, Erlich S. Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration. Nucleic Acid Ther. 2012 Aug; 22(4):255-64. PMID: 22913596.
      View in: PubMed
    71. Saleh MA, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Molitoris BA, Pollock DM. Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat. Life Sci. 2012 Oct 15; 91(13-14):634-7. PMID: 22727794.
      View in: PubMed
    72. Imamura R, Isaka Y, Sandoval RM, Ichimaru N, Abe T, Okumi M, Yazawa K, Kitamura H, Kaimori J, Nonomura N, Rakugi H, Molitoris BA, Takahara S. A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney. Clin Exp Nephrol. 2012 Dec; 16(6):852-62. PMID: 22678524.
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    73. Molitoris BA, Okusa MD, Palevsky PM, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Faubel SG, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings. Clin J Am Soc Nephrol. 2012 May; 7(5):856-60. PMID: 22442184.
      View in: PubMed
    74. Molitoris BA, Okusa MD, Palevsky PM, Kimmel PL, Star RA. Designing clinical trials in acute kidney injury. Clin J Am Soc Nephrol. 2012 May; 7(5):842-3. PMID: 22442185.
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    75. Okusa MD, Molitoris BA, Palevsky PM, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Faubel S, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials. Clin J Am Soc Nephrol. 2012 May; 7(5):851-5. PMID: 22442188.
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    76. Palevsky PM, Molitoris BA, Okusa MD, Levin A, Waikar SS, Wald R, Chertow GM, Murray PT, Parikh CR, Shaw AD, Go AS, Faubel SG, Kellum JA, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene T, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol. 2012 May; 7(5):844-50. PMID: 22442182.
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    77. Sandoval RM, Wagner MC, Patel M, Campos-Bilderback SB, Rhodes GJ, Wang E, Wean SE, Clendenon SS, Molitoris BA. Multiple factors influence glomerular albumin permeability in rats. J Am Soc Nephrol. 2012 Mar; 23(3):447-57. PMID: 22223875.
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    78. Choong FX, Sandoval RM, Molitoris BA, Richter-Dahlfors A. Multiphoton microscopy applied for real-time intravital imaging of bacterial infections in vivo. Methods Enzymol. 2012; 506:35-61. PMID: 22341218.
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    79. Molitoris BA, Sandoval RM. Kidney endothelial dysfunction: ischemia, localized infections and sepsis. Contrib Nephrol. 2011; 174:108-118. PMID: 21921615.
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    80. Wang E, Meier DJ, Sandoval RM, Von Hendy-Willson VE, Pressler BM, Bunch RM, Alloosh M, Sturek MS, Schwartz GJ, Molitoris BA. A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals. Kidney Int. 2012 Jan; 81(1):112-7. PMID: 21881552.
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    81. Molitoris JK, Molitoris BA. Circulating micro-RNAs in acute kidney injury: early observations. Clin J Am Soc Nephrol. 2011 Jul; 6(7):1517-9. PMID: 21734080.
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    82. Presson RG, Brown MB, Fisher AJ, Sandoval RM, Dunn KW, Lorenz KS, Delp EJ, Salama P, Molitoris BA, Petrache I. Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact. Am J Pathol. 2011 Jul; 179(1):75-82. PMID: 21703395.
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    83. Parker MG, Ibrahim T, Shaffer R, Rosner MH, Molitoris BA. The future nephrology workforce: will there be one? Clin J Am Soc Nephrol. 2011 Jun; 6(6):1501-6. PMID: 21551020.
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    84. Mehrotra R, Shaffer RN, Molitoris BA. Implications of a nephrology workforce shortage for dialysis patient care. Semin Dial. 2011 May-Jun; 24(3):275-7. PMID: 21682769.
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    85. Molitoris BA. Disease-specific kidney imaging: introduction. Semin Nephrol. 2011 May; 31(3):235-6. PMID: 21784271.
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    86. Sharfuddin AA, Molitoris BA. Pathophysiology of ischemic acute kidney injury. Nat Rev Nephrol. 2011 Apr; 7(4):189-200. PMID: 21364518.
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    87. Melican K, Sandoval RM, Kader A, Josefsson L, Tanner GA, Molitoris BA, Richter-Dahlfors A. Uropathogenic Escherichia coli P and Type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction. PLoS Pathog. 2011 Feb; 7(2):e1001298. PMID: 21383970.
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    88. Anderson S, Eldadah B, Halter JB, Hazzard WR, Himmelfarb J, Horne FM, Kimmel PL, Molitoris BA, Murthy M, O'Hare AM, Schmader KE, High KP. Acute kidney injury in older adults. J Am Soc Nephrol. 2011 Jan; 22(1):28-38. PMID: 21209252.
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    89. Basile DP, Friedrich JL, Spahic J, Knipe N, Mang H, Leonard EC, Changizi-Ashtiyani S, Bacallao RL, Molitoris BA, Sutton TA. Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury. Am J Physiol Renal Physiol. 2011 Mar; 300(3):F721-33. PMID: 21123492.
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    90. Molitoris BA. Yet another advance in understanding albuminuria? J Am Soc Nephrol. 2010 Dec; 21(12):2013-5. PMID: 21051742.
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    91. Lin L, Wagner MC, Cocklin R, Kuzma A, Harrington M, Molitoris BA, Goebl MG. The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases. Antimicrob Agents Chemother. 2011 Jan; 55(1):246-54. PMID: 20956596.
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    92. Portilla D, Shaffer RN, Okusa MD, Mehrotra R, Molitoris BA, Bunchman TE, Ibrahim T. Lessons from Haiti on disaster relief. Clin J Am Soc Nephrol. 2010 Nov; 5(11):2122-9. PMID: 20947792.
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    93. Imamura R, Isaka Y, Sandoval RM, Ori A, Adamsky S, Feinstein E, Molitoris BA, Takahara S. Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models. Cell Transplant. 2010; 19(12):1659-70. PMID: 20719069.
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    94. Wang E, Sandoval RM, Campos SB, Molitoris BA. Rapid diagnosis and quantification of acute kidney injury using fluorescent ratio-metric determination of glomerular filtration rate in the rat. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F1048-55. PMID: 20685826.
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    95. Molitoris BA, Sandoval RM. Multiphoton imaging techniques in acute kidney injury. Contrib Nephrol. 2010; 165:46-53. PMID: 20427955.
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    96. Gupta A, Williams MD, Macias WL, Molitoris BA, Grinnell BW. Activated protein C and acute kidney injury: Selective targeting of PAR-1. Curr Drug Targets. 2009 Dec; 10(12):1212-26. PMID: 19715537.
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    97. Atthe BK, Babsky AM, Hopewell PN, Phillips CL, Molitoris BA, Bansal N. Early monitoring of acute tubular necrosis in the rat kidney by 23Na-MRI. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1288-98. PMID: 19726545.
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    98. Stokes JB, Haupt A, Molitoris BA, Kokemueller P, Ibrahim T. ASN policy on managing conflicts of interest. J Am Soc Nephrol. 2009 Sep; 20(9):1853-9. PMID: 19713305.
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    99. Stokes JB, Berns AS, Henrich WL, McKinney TD, Molitoris BA, Palmer BF. Managing conflicts of interest: the road ahead. J Am Soc Nephrol. 2009 Sep; 20(9):1860-2. PMID: 19713304.
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    100. Molitoris BA, Dagher PC, Sandoval RM, Campos SB, Ashush H, Fridman E, Brafman A, Faerman A, Atkinson SJ, Thompson JD, Kalinski H, Skaliter R, Erlich S, Feinstein E. siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury. J Am Soc Nephrol. 2009 Aug; 20(8):1754-64. PMID: 19470675.
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    101. Weinberg JM, Molitoris BA. Illuminating mitochondrial function and dysfunction using multiphoton technology. J Am Soc Nephrol. 2009 Jun; 20(6):1164-6. PMID: 19470668.
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    102. Hingorani S, Molitoris BA, Himmelfarb J. Ironing out the pathogenesis of acute kidney injury. Am J Kidney Dis. 2009 Apr; 53(4):569-71. PMID: 19324244.
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    103. Sharfuddin AA, Sandoval RM, Berg DT, McDougal GE, Campos SB, Phillips CL, Jones BE, Gupta A, Grinnell BW, Molitoris BA. Soluble thrombomodulin protects ischemic kidneys. J Am Soc Nephrol. 2009 Mar; 20(3):524-34. PMID: 19176699.
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    104. Molitoris BA, Sandoval RM. Techniques to study nephron function: microscopy and imaging. Pflugers Arch. 2009 May; 458(1):203-9. PMID: 19145447.
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    105. Campos SB, Ashworth SL, Wean S, Hosford M, Sandoval RM, Hallett MA, Atkinson SJ, Molitoris BA. Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation. Am J Physiol Renal Physiol. 2009 Mar; 296(3):F487-95. PMID: 19144696.
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    106. Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D. Impaired tubular uptake explains albuminuria in early diabetic nephropathy. J Am Soc Nephrol. 2009 Mar; 20(3):489-94. PMID: 19118149.
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    107. Ishani A, Xue JL, Himmelfarb J, Eggers PW, Kimmel PL, Molitoris BA, Collins AJ. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol. 2009 Jan; 20(1):223-8. PMID: 19020007.
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    108. Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D. Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1. J Biol Chem. 2008 Dec 19; 283(51):35579-89. PMID: 18922801.
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    109. Sharfuddin AA, Sandoval RM, Molitoris BA. Imaging techniques in acute kidney injury. Nephron Clin Pract. 2008; 109(4):c198-204. PMID: 18802368.
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    110. Molitoris BA. Contrast nephropathy: are short-term outcome measures adequate for quantification of long-term renal risk? Nat Clin Pract Nephrol. 2008 Nov; 4(11):594-5. PMID: 18779854.
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    111. Melnikov VY, Molitoris BA. Improvements in the diagnosis of acute kidney injury. Saudi J Kidney Dis Transpl. 2008 Jul; 19(4):537-44. PMID: 18580009.
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    112. Melican K, Boekel J, M?nsson LE, Sandoval RM, Tanner GA, K?llskog O, Palm F, Molitoris BA, Richter-Dahlfors A. Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis. Cell Microbiol. 2008 Oct; 10(10):1987-98. PMID: 18549455.
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    113. Himmelfarb J, Joannidis M, Molitoris B, Schietz M, Okusa MD, Warnock D, Laghi F, Goldstein SL, Prielipp R, Parikh CR, Pannu N, Lobo SM, Shah S, D'Intini V, Kellum JA. Evaluation and initial management of acute kidney injury. Clin J Am Soc Nephrol. 2008 Jul; 3(4):962-7. PMID: 18354074.
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    114. Molitoris BA, Melnikov VY, Okusa MD, Himmelfarb J. Technology Insight: biomarker development in acute kidney injury--what can we anticipate? Nat Clin Pract Nephrol. 2008 Mar; 4(3):154-65. PMID: 18227821.
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    115. Kellum JA, Mehta RL, Levin A, Molitoris BA, Warnock DG, Shah SV, Joannidis M, Ronco C. Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified Delphi process. Clin J Am Soc Nephrol. 2008 May; 3(3):887-94. PMID: 18216348.
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    116. Sandoval RM, Molitoris BA. Quantifying endocytosis in vivo using intravital two-photon microscopy. Methods Mol Biol. 2008; 440:389-402. PMID: 18369960.
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    117. Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD. Controversies in nephrology: response to 'renal albumin handling, facts, and artifacts'. Kidney Int. 2007 Nov; 72(10):1195-7. PMID: 17851467.
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    118. Molitoris BA, Levin A, Warnock DG, Joannidis M, Mehta RL, Kellum JA, Ronco C, Shah SV. Improving outcomes of acute kidney injury: report of an initiative. Nat Clin Pract Nephrol. 2007 Aug; 3(8):439-42. PMID: 17653122.
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    119. Bagga A, Bakkaloglu A, Devarajan P, Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Joannidis M, Levin A. Improving outcomes from acute kidney injury: report of an initiative. Pediatr Nephrol. 2007 Oct; 22(10):1655-8. PMID: 17665221.
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    120. M?nsson LE, Melican K, Molitoris BA, Richter-Dahlfors A. Progression of bacterial infections studied in real time--novel perspectives provided by multiphoton microscopy. Cell Microbiol. 2007 Oct; 9(10):2334-43. PMID: 17662072.
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    121. Molitoris BA, Levin A, Warnock DG, Joannidis M, Mehta RL, Kellum JA, Ronco C, Shah S. Improving outcomes from acute kidney injury. J Am Soc Nephrol. 2007 Jul; 18(7):1992-4. PMID: 17596636.
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    122. Levin A, Warnock DG, Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C. Improving outcomes from acute kidney injury: report of an initiative. Am J Kidney Dis. 2007 Jul; 50(1):1-4. PMID: 17591518.
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    123. Ashworth SL, Sandoval RM, Tanner GA, Molitoris BA. Two-photon microscopy: visualization of kidney dynamics. Kidney Int. 2007 Aug; 72(4):416-21. PMID: 17538570.
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    124. H?rbelt M, Wotzlaw C, Sutton TA, Molitoris BA, Philipp T, Kribben A, Fandrey J, Pietruck F. Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy. Kidney Int. 2007 Aug; 72(4):422-9. PMID: 17495857.
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    125. Ronco C, Levin A, Warnock DG, Mehta R, Kellum JA, Shah S, Molitoris BA. Improving outcomes from acute kidney injury (AKI): Report on an initiative. Int J Artif Organs. 2007 May; 30(5):373-6. PMID: 17551899.
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    126. Gupta A, Rhodes GJ, Berg DT, Gerlitz B, Molitoris BA, Grinnell BW. Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F245-54. PMID: 17409278.
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    127. Yu W, Sandoval RM, Molitoris BA. Rapid determination of renal filtration function using an optical ratiometric imaging approach. Am J Physiol Renal Physiol. 2007 Jun; 292(6):F1873-80. PMID: 17311910.
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    128. Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD. The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007 Mar; 71(6):504-13. PMID: 17228368.
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    129. Molitoris BA, Sandoval RM. Quantifying dynamic kidney processes utilizing multi-photon microscopy. Contrib Nephrol. 2007; 156:227-35. PMID: 17464132.
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    130. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007; 11(2):R31. PMID: 17331245.
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    131. Sandoval RM, Reilly JP, Running W, Campos SB, Santos JR, Phillips CL, Molitoris BA. A non-nephrotoxic gentamicin congener that retains antimicrobial efficacy. J Am Soc Nephrol. 2006 Oct; 17(10):2697-705. PMID: 16971659.
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    132. Molitoris BA, Sandoval RM. Pharmacophotonics: utilizing multi-photon microscopy to quantify drug delivery and intracellular trafficking in the kidney. Adv Drug Deliv Rev. 2006 Sep 15; 58(7):809-23. PMID: 17064810.
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    133. M?nsson LE, Melican K, Boekel J, Sandoval RM, Hautefort I, Tanner GA, Molitoris BA, Richter-Dahlfors A. Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals. Cell Microbiol. 2007 Feb; 9(2):413-24. PMID: 16953802.
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    134. Herget-Rosenthal S, Molitoris BA. Advances in imaging the kidney and cellular processes. Nephron Exp Nephrol. 2006; 103(2):e31-2. PMID: 16543761.
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    135. Xue JL, Daniels F, Star RA, Kimmel PL, Eggers PW, Molitoris BA, Himmelfarb J, Collins AJ. Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001. J Am Soc Nephrol. 2006 Apr; 17(4):1135-42. PMID: 16495381.
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    136. Wagner MC, Molnar EE, Molitoris BA, Goebl MG. Loss of the homotypic fusion and vacuole protein sorting or golgi-associated retrograde protein vesicle tethering complexes results in gentamicin sensitivity in the yeast Saccharomyces cerevisiae. Antimicrob Agents Chemother. 2006 Feb; 50(2):587-95. PMID: 16436714.
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    137. Suurna MV, Ashworth SL, Hosford M, Sandoval RM, Wean SE, Shah BM, Bamburg JR, Molitoris BA. Cofilin mediates ATP depletion-induced endothelial cell actin alterations. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1398-407. PMID: 16434575.
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    138. Raikwar SP, Temm CJ, Raikwar NS, Kao C, Molitoris BA, Gardner TA. Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model. Mol Ther. 2005 Dec; 12(6):1091-100. PMID: 16169279.
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    139. Yu W, Sandoval RM, Molitoris BA. Quantitative intravital microscopy using a Generalized Polarity concept for kidney studies. Am J Physiol Cell Physiol. 2005 Nov; 289(5):C1197-208. PMID: 16033906.
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    140. Molitoris BA. Renal blood flow in sepsis: a complex issue. Crit Care. 2005 Aug; 9(4):327-8. PMID: 16137373.
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    141. Molitoris BA, Sandoval RM. Intravital multiphoton microscopy of dynamic renal processes. Am J Physiol Renal Physiol. 2005 Jun; 288(6):F1084-9. PMID: 15883167.
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    142. Tanner GA, Sandoval RM, Molitoris BA, Bamburg JR, Ashworth SL. Micropuncture gene delivery and intravital two-photon visualization of protein expression in rat kidney. Am J Physiol Renal Physiol. 2005 Sep; 289(3):F638-43. PMID: 15886277.
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    143. Molitoris BA, Sutton TA. Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int. 2004 Aug; 66(2):496-9. PMID: 15253696.
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    144. Molitoris BA. Actin cytoskeleton in ischemic acute renal failure. Kidney Int. 2004 Aug; 66(2):871-83. PMID: 15253754.
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    145. Sandoval RM, Kennedy MD, Low PS, Molitoris BA. Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy. Am J Physiol Cell Physiol. 2004 Aug; 287(2):C517-26. PMID: 15102609.
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    146. Ashworth SL, Wean SE, Campos SB, Temm-Grove CJ, Southgate EL, Vrhovski B, Gunning P, Weinberger RP, Molitoris BA. Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments. Am J Physiol Renal Physiol. 2004 May; 286(5):F988-96. PMID: 15075195.
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    147. Sandoval RM, Molitoris BA. Gentamicin traffics retrograde through the secretory pathway and is released in the cytosol via the endoplasmic reticulum. Am J Physiol Renal Physiol. 2004 Apr; 286(4):F617-24. PMID: 14625200.
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    148. Atkinson SJ, Hosford MA, Molitoris BA. Mechanism of actin polymerization in cellular ATP depletion. J Biol Chem. 2004 Feb 13; 279(7):5194-9. PMID: 14623892.
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    149. Dagher PC, Herget-Rosenthal S, Ruehm SG, Jo SK, Star RA, Agarwal R, Molitoris BA. Newly developed techniques to study and diagnose acute renal failure. J Am Soc Nephrol. 2003 Aug; 14(8):2188-98. PMID: 12874475.
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    150. Kwon O, Molitoris BA, Pescovitz M, Kelly KJ. Urinary actin, interleukin-6, and interleukin-8 may predict sustained ARF after ischemic injury in renal allografts. Am J Kidney Dis. 2003 May; 41(5):1074-87. PMID: 12722043.
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    151. Sutton TA, Mang HE, Campos SB, Sandoval RM, Yoder MC, Molitoris BA. Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol Renal Physiol. 2003 Aug; 285(2):F191-8. PMID: 12684225.
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    152. Dunn KW, Sandoval RM, Molitoris BA. Intravital imaging of the kidney using multiparameter multiphoton microscopy. Nephron Exp Nephrol. 2003; 94(1):e7-11. PMID: 12806182.
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    153. Molitoris BA. Transitioning to therapy in ischemic acute renal failure. J Am Soc Nephrol. 2003 Jan; 14(1):265-7. PMID: 12506160.
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    154. Kelly KJ, Sandoval RM, Dunn KW, Molitoris BA, Dagher PC. A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis. Am J Physiol Cell Physiol. 2003 May; 284(5):C1309-18. PMID: 12676658.
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    155. Ashworth SL, Southgate EL, Sandoval RM, Meberg PJ, Bamburg JR, Molitoris BA. ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion. Am J Physiol Renal Physiol. 2003 Apr; 284(4):F852-62. PMID: 12620926.
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    156. Dunn KW, Sandoval RM, Kelly KJ, Dagher PC, Tanner GA, Atkinson SJ, Bacallao RL, Molitoris BA. Functional studies of the kidney of living animals using multicolor two-photon microscopy. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C905-16. PMID: 12176747.
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    157. Kwon O, Phillips CL, Molitoris BA. Ischemia induces alterations in actin filaments in renal vascular smooth muscle cells. Am J Physiol Renal Physiol. 2002 Jun; 282(6):F1012-9. PMID: 11997317.
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    158. Molitoris BA, Sandoval R, Sutton TA. Endothelial injury and dysfunction in ischemic acute renal failure. Crit Care Med. 2002 May; 30(5 Suppl):S235-40. PMID: 12004242.
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    159. Herget-Rosenthal S, Hosford M, Kribben A, Atkinson SJ, Sandoval RM, Molitoris BA. Characteristics of EYFP-actin and visualization of actin dynamics during ATP depletion and repletion. Am J Physiol Cell Physiol. 2001 Dec; 281(6):C1858-70. PMID: 11698244.
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    160. Ashworth SL, Sandoval RM, Hosford M, Bamburg JR, Molitoris BA. Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells. Am J Physiol Renal Physiol. 2001 May; 280(5):F886-94. PMID: 11292632.
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    161. Sundin DP, Sandoval R, Molitoris BA. Gentamicin inhibits renal protein and phospholipid metabolism in rats: implications involving intracellular trafficking. J Am Soc Nephrol. 2001 Jan; 12(1):114-123. PMID: 11134257.
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    162. Sandoval RM, Dunn KW, Molitoris BA. Gentamicin traffics rapidly and directly to the Golgi complex in LLC-PK(1) cells. Am J Physiol Renal Physiol. 2000 Nov; 279(5):F884-90. PMID: 11053049.
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    163. Yaqub MS, Molitoris BA. Dialytic care of patients with acute renal failure. Drugs Today (Barc). 2000 Jan; 36(1):13-24. PMID: 12879101.
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    164. Kelly KJ, Molitoris BA. Acute renal failure in the new millennium: time to consider combination therapy. Semin Nephrol. 2000 Jan; 20(1):4-19. PMID: 10651214.
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    165. Molitoris BA. Acute renal failure. Drugs Today (Barc). 1999 Sep; 35(9):659-66. PMID: 12973464.
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    166. Ashworth SL, Molitoris BA. Pathophysiology and functional significance of apical membrane disruption during ischemia. Curr Opin Nephrol Hypertens. 1999 Jul; 8(4):449-58. PMID: 10491740.
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    167. Molitoris BA, Marrs J. The role of cell adhesion molecules in ischemic acute renal failure. Am J Med. 1999 May; 106(5):583-92. PMID: 10335732.
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    168. Schwartz N, Hosford M, Sandoval RM, Wagner MC, Atkinson SJ, Bamburg J, Molitoris BA. Ischemia activates actin depolymerizing factor: role in proximal tubule microvillar actin alterations. Am J Physiol. 1999 04; 276(4):F544-51. PMID: 10198413.
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    169. Wagner MC, Molitoris BA. Renal epithelial polarity in health and disease. Pediatr Nephrol. 1999 Feb; 13(2):163-70. PMID: 10229007.
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    170. Sutton TA, Molitoris BA. Mechanisms of cellular injury in ischemic acute renal failure. Semin Nephrol. 1998 Sep; 18(5):490-7. PMID: 9754601.
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    171. Molitoris BA. Ischemic acute renal failure: exciting times at our fingertips. Curr Opin Nephrol Hypertens. 1998 Jul; 7(4):405-6. PMID: 9690039.
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    172. Sandoval R, Leiser J, Molitoris BA. Aminoglycoside antibiotics traffic to the Golgi complex in LLC-PK1 cells. J Am Soc Nephrol. 1998 Feb; 9(2):167-74. PMID: 9527392.
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    173. Molitoris BA, Leiser J, Wagner MC. Role of the actin cytoskeleton in ischemia-induced cell injury and repair. Pediatr Nephrol. 1997 Dec; 11(6):761-7. PMID: 9438662.
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    174. Molitoris BA. Cell biology of aminoglycoside nephrotoxicity: newer aspects. Curr Opin Nephrol Hypertens. 1997 Jul; 6(4):384-8. PMID: 9263689.
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    175. Wagner MC, Molitoris BA. ATP depletion alters myosin I beta cellular location in LLC-PK1 cells. Am J Physiol. 1997 May; 272(5 Pt 1):C1680-90. PMID: 9176160.
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    176. DuBose TD, Warnock DG, Mehta RL, Bonventre JV, Hammerman MR, Molitoris BA, Paller MS, Siegel NJ, Scherbenske J, Striker GE. Acute renal failure in the 21st century: recommendations for management and outcomes assessment. Am J Kidney Dis. 1997 May; 29(5):793-9. PMID: 9159318.
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    177. Molitoris BA. Putting the actin cytoskeleton into perspective: pathophysiology of ischemic alterations. Am J Physiol. 1997 Apr; 272(4 Pt 2):F430-3. PMID: 9140042.
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    178. Sundin DP, Meyer C, Dahl R, Geerdes A, Sandoval R, Molitoris BA. Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment. Am J Physiol. 1997 Apr; 272(4 Pt 1):C1309-18. PMID: 9142857.
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    179. Molitoris BA, Dahl R, Hosford M. Cellular ATP depletion induces disruption of the spectrin cytoskeletal network. Am J Physiol. 1996 Oct; 271(4 Pt 2):F790-8. PMID: 8898008.
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    180. Molitoris BA, Wagner MC. Surface membrane polarity of proximal tubular cells: alterations as a basis for malfunction. Kidney Int. 1996 Jun; 49(6):1592-7. PMID: 8743461.
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    181. Clark WR, Macias WL, Molitoris BA, Wang NH. Plasma protein adsorption to highly permeable hemodialysis membranes. Kidney Int. 1995 Aug; 48(2):481-8. PMID: 7564116.
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    182. Ford DM, Thieme RE, Lamp CA, Covington SJ, Molitoris BA. HWA-448 reduces gentamicin toxicity in LLC-PK1 cells. J Pharmacol Exp Ther. 1995 Jul; 274(1):29-33. PMID: 7616411.
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    183. Cohen M, Sundin DP, Dahl R, Molitoris BA. Convergence of apical and basolateral endocytic pathways for beta 2-microglobulin in LLC-PK1 cells. Am J Physiol. 1995 May; 268(5 Pt 2):F829-38. PMID: 7771511.
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    184. Clark WR, Macias WL, Molitoris BA, Wang NH. Membrane adsorption of beta 2-microglobulin: equilibrium and kinetic characterization. Kidney Int. 1994 Oct; 46(4):1140-6. PMID: 7861709.
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    185. Fish EM, Molitoris BA. Extracellular acidosis minimizes actin cytoskeletal alterations during ATP depletion. Am J Physiol. 1994 Oct; 267(4 Pt 2):F566-72. PMID: 7943355.
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    186. Sundin DP, Cohen M, Dahl R, Falk S, Molitoris BA. Characterization of the beta 2-microglobulin endocytic pathway in rat proximal tubule cells. Am J Physiol. 1994 Sep; 267(3 Pt 2):F380-9. PMID: 8092252.
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    187. Leiser J, Molitoris BA. Disease processes in epithelia: the role of the actin cytoskeleton and altered surface membrane polarity. Biochim Biophys Acta. 1993 Nov 25; 1225(1):1-13. PMID: 8241285.
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    188. Molitoris BA. Na(+)-K(+)-ATPase that redistributes to apical membrane during ATP depletion remains functional. Am J Physiol. 1993 Nov; 265(5 Pt 2):F693-7. PMID: 8238549.
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    189. Molitoris BA, Meyer C, Dahl R, Geerdes A. Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells. Am J Physiol. 1993 May; 264(5 Pt 2):F907-16. PMID: 8498544.
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    190. Molitoris BA, Dahl R, Geerdes A. Role of the actin cytoskeleton in ischemic injury. Chest. 1992 Mar; 101(3 Suppl):52S-53S. PMID: 1541205.
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    191. Canfield PE, Geerdes AM, Molitoris BA. Effect of reversible ATP depletion on tight-junction integrity in LLC-PK1 cells. Am J Physiol. 1991 Dec; 261(6 Pt 2):F1038-45. PMID: 1721494.
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    192. Molitoris BA, Geerdes A, McIntosh JR. Dissociation and redistribution of Na+,K(+)-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion. J Clin Invest. 1991 Aug; 88(2):462-9. PMID: 1650794.
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    193. Molitoris BA. New insights into the cell biology of ischemic acute renal failure. J Am Soc Nephrol. 1991 Jun; 1(12):1263-70. PMID: 1912388.
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    194. Spiegel DM, Shanley PF, Molitoris BA. Mild ischemia predisposes the S3 segment to gentamicin toxicity. Kidney Int. 1990 Sep; 38(3):459-64. PMID: 2232488.
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    195. Kellerman PS, Clark RA, Hoilien CA, Linas SL, Molitoris BA. Role of microfilaments in maintenance of proximal tubule structural and functional integrity. Am J Physiol. 1990 Aug; 259(2 Pt 2):F279-85. PMID: 2386206.
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    196. Molitoris BA, Falk SA, Dahl RH. Ischemia-induced loss of epithelial polarity. Role of the tight junction. J Clin Invest. 1989 Oct; 84(4):1334-9. PMID: 2551926.
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    197. Spiegel DM, Wilson PD, Molitoris BA. Epithelial polarity following ischemia: a requirement for normal cell function. Am J Physiol. 1989 Mar; 256(3 Pt 2):F430-6. PMID: 2538079.
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    198. Molitoris BA, Chan LK, Shapiro JI, Conger JD, Falk SA. Loss of epithelial polarity: a novel hypothesis for reduced proximal tubule Na+ transport following ischemic injury. J Membr Biol. 1989 Feb; 107(2):119-27. PMID: 2541248.
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    199. Molitoris BA, Hoilien CA, Dahl R, Ahnen DJ, Wilson PD, Kim J. Characterization of ischemia-induced loss of epithelial polarity. J Membr Biol. 1988 Dec; 106(3):233-42. PMID: 2468776.
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    200. Molitoris BA, Kinne R. Ischemia induces surface membrane dysfunction. Mechanism of altered Na+-dependent glucose transport. J Clin Invest. 1987 Sep; 80(3):647-54. PMID: 3624482.
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    201. Molitoris BA, Hoilien C. Static and dynamic components of renal cortical brush border and basolateral membrane fluidity: role of cholesterol. J Membr Biol. 1987; 99(3):165-72. PMID: 3694671.
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    202. Molitoris BA, Wilson PD, Schrier RW, Simon FR. Ischemia induces partial loss of surface membrane polarity and accumulation of putative calcium ionophores. J Clin Invest. 1985 Dec; 76(6):2097-105. PMID: 3001141.
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    203. Molitoris BA, Simon FR. Renal cortical brush-border and basolateral membranes: cholesterol and phospholipid composition and relative turnover. J Membr Biol. 1985; 83(3):207-15. PMID: 3999120.
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