 Kidney Tubules, Proximal
"Kidney Tubules, Proximal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The renal tubule portion that extends from the BOWMAN CAPSULE in the KIDNEY CORTEX into the KIDNEY MEDULLA. The proximal tubule consists of a convoluted proximal segment in the cortex, and a distal straight segment descending into the medulla where it forms the U-shaped LOOP OF HENLE.
| Descriptor ID |
D007687
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| MeSH Number(s) |
A05.810.453.736.560.570
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| Concept/Terms |
Kidney Tubules, Proximal- Kidney Tubules, Proximal
- Kidney Tubule, Proximal
- Proximal Kidney Tubules
- Tubule, Proximal Kidney
- Tubules, Proximal Kidney
- Proximal Renal Tubule
- Proximal Renal Tubules
- Renal Tubule, Proximal
- Renal Tubules, Proximal
- Tubule, Proximal Renal
- Tubules, Proximal Renal
- Proximal Kidney Tubule
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Below are MeSH descriptors whose meaning is more general than "Kidney Tubules, Proximal".
Below are MeSH descriptors whose meaning is more specific than "Kidney Tubules, Proximal".
This graph shows the total number of publications written about "Kidney Tubules, Proximal" by people in this website by year, and whether "Kidney Tubules, Proximal" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 0 | 3 | | 1996 | 7 | 0 | 7 | | 1997 | 3 | 1 | 4 | | 1998 | 1 | 0 | 1 | | 1999 | 3 | 0 | 3 | | 2000 | 3 | 0 | 3 | | 2001 | 2 | 1 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 2 | 0 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 3 | 5 | | 2008 | 3 | 0 | 3 | | 2009 | 3 | 0 | 3 | | 2010 | 2 | 0 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 2 | 5 | | 2013 | 1 | 1 | 2 | | 2014 | 5 | 1 | 6 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 3 | 1 | 4 | | 2020 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 2 | 1 | 3 | | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Kidney Tubules, Proximal" by people in Profiles.
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Wagner MC, Sandoval RM, Yadav SPS, Campos SB, Rhodes GJ, Phillips CL, Molitoris BA. Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity. Kidney360. 2023 05 01; 4(5):591-605.
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Bryniarski MA, Sandoval RM, Ruszaj DM, Fraser-McArthur J, Yee BM, Yacoub R, Chaves LD, Campos-Bilderback SB, Molitoris BA, Morris ME. Defining the Intravital Renal Disposition of Fluorescence-Quenched Exenatide. Mol Pharm. 2023 02 06; 20(2):987-996.
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Yadav SPS, Yu A, Zhao J, Singh J, Kakkar S, Chakraborty S, Mechref Y, Molitoris B, Wagner MC. Glycosylation of a key cubilin Asn residue results in reduced binding to albumin. J Biol Chem. 2022 10; 298(10):102371.
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Miyazaki-Anzai S, Keenan AL, Blaine J, Miyazaki M. Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification. J Am Soc Nephrol. 2022 08; 33(8):1477-1486.
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Molitoris BA, Sandoval RM, Yadav SPS, Wagner MC. Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications. Physiol Rev. 2022 10 01; 102(4):1625-1667.
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Blaine J. Generating a Podocyte-Specific Neonatal F Receptor (FcRn) Knockout Mouse. Methods Mol Biol. 2021; 2224:123-132.
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Yadav SPS, Sandoval RM, Zhao J, Huang Y, Wang E, Kumar S, Campos-Bilderback SB, Rhodes G, Mechref Y, Molitoris BA, Wagner MC. Mechanism of how carbamylation reduces albumin binding to FcRn contributing to increased vascular clearance. Am J Physiol Renal Physiol. 2021 01 01; 320(1):F114-F129.
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Nakagawa T, Johnson RJ, Andres-Hernando A, Roncal-Jimenez C, Sanchez-Lozada LG, Tolan DR, Lanaspa MA. Fructose Production and Metabolism in the Kidney. J Am Soc Nephrol. 2020 05; 31(5):898-906.
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Liu XF, Wei J, Zhou Q, Molitoris BA, Sandoval R, Kobayashi H, Okada R, Nagaya T, Karim B, Butcher D, Pastan I. Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):6086-6091.
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Molitoris BA. DNA damage response protects against progressive kidney disease. J Clin Invest. 2019 11 01; 129(11):4574-4575.
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