 DNA-Activated Protein Kinase
"DNA-Activated Protein Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine-threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding protein substrates including the TUMOR SUPPRESSOR PROTEIN P53 and a variety of TRANSCRIPTION FACTORS.
| Descriptor ID |
D051747
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| MeSH Number(s) |
D08.811.913.696.620.682.700.250 D12.776.157.687.438 D12.776.660.720.438
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| Concept/Terms |
DNA-Activated Protein Kinase- DNA-Activated Protein Kinase
- DNA Activated Protein Kinase
- Kinase, DNA-Activated Protein
- Protein Kinase, DNA-Activated
- DNA-Dependent Protein Serine-Threonine Kinase
- DNA Dependent Protein Serine Threonine Kinase
- DNA-Dependent Protein Kinase
- DNA Dependent Protein Kinase
- Kinase, DNA-Dependent Protein
- Protein Kinase, DNA-Dependent
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Below are MeSH descriptors whose meaning is more general than "DNA-Activated Protein Kinase".
Below are MeSH descriptors whose meaning is more specific than "DNA-Activated Protein Kinase".
This graph shows the total number of publications written about "DNA-Activated Protein Kinase" by people in this website by year, and whether "DNA-Activated Protein Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2014 | 1 | 2 | 3 |
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Below are the most recent publications written about "DNA-Activated Protein Kinase" by people in Profiles.
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Bunch H, Zheng X, Burkholder A, Dillon ST, Motola S, Birrane G, Ebmeier CC, Levine S, Fargo D, Hu G, Taatjes DJ, Calderwood SK. TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release. Nat Struct Mol Biol. 2014 Oct; 21(10):876-83.
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Ashley AK, Shrivastav M, Nie J, Amerin C, Troksa K, Glanzer JG, Liu S, Opiyo SO, Dimitrova DD, Le P, Sishc B, Bailey SM, Oakley GG, Nickoloff JA. DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe. DNA Repair (Amst). 2014 Sep; 21:131-9.
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Inturi S, Tewari-Singh N, Agarwal C, White CW, Agarwal R. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes. Mutat Res. 2014 May-Jun; 763-764:53-63.
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Nichols GJ, Schaack J, Ornelles DA. Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication. J Virol. 2009 Jun; 83(12):5987-98.
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Li HR, Shagisultanova EI, Yamashita K, Piao Z, Perucho M, Malkhosyan SR. Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin. Cancer Res. 2004 Jul 15; 64(14):4760-7.
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Faiola B, Bauer AK, Fuller ES, Wong VA, Pluta LJ, Abernethy DJ, Mangum JB, Everitt JI, Recio L. Variations in Prkdc and susceptibility to benzene-induced toxicity in mice. Toxicol Sci. 2003 Oct; 75(2):321-32.
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Sartorius CA, Takimoto GS, Richer JK, Tung L, Horwitz KB. Association of the Ku autoantigen/DNA-dependent protein kinase holoenzyme and poly(ADP-ribose) polymerase with the DNA binding domain of progesterone receptors. J Mol Endocrinol. 2000 Apr; 24(2):165-82.
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