 Deuterium Exchange Measurement
"Deuterium Exchange Measurement" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.
| Descriptor ID |
D041961
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| MeSH Number(s) |
E05.196.344
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| Concept/Terms |
Deuterium Exchange Measurement- Deuterium Exchange Measurement
- Deuterium Exchange Measurements
- Exchange Measurement, Deuterium
- Exchange Measurements, Deuterium
- Measurement, Deuterium Exchange
- Measurements, Deuterium Exchange
- Hydrogen-Deuterium Exchange Measurement
- Exchange Measurement, Hydrogen-Deuterium
- Exchange Measurements, Hydrogen-Deuterium
- Hydrogen Deuterium Exchange Measurement
- Hydrogen-Deuterium Exchange Measurements
- Measurement, Hydrogen-Deuterium Exchange
- Measurements, Hydrogen-Deuterium Exchange
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Below are MeSH descriptors whose meaning is more general than "Deuterium Exchange Measurement".
Below are MeSH descriptors whose meaning is more specific than "Deuterium Exchange Measurement".
This graph shows the total number of publications written about "Deuterium Exchange Measurement" by people in this website by year, and whether "Deuterium Exchange Measurement" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 1 | 3 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deuterium Exchange Measurement" by people in Profiles.
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Bester SM, Wei G, Zhao H, Adu-Ampratwum D, Iqbal N, Courouble VV, Francis AC, Annamalai AS, Singh PK, Shkriabai N, Van Blerkom P, Morrison J, Poeschla EM, Engelman AN, Melikyan GB, Griffin PR, Fuchs JR, Asturias FJ, Kvaratskhelia M. Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science. 2020 10 16; 370(6514):360-364.
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Pegram LM, Liddle JC, Xiao Y, Hoh M, Rudolph J, Iverson DB, Vigers GP, Smith D, Zhang H, Wang W, Moffat JG, Ahn NG. Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc Natl Acad Sci U S A. 2019 07 30; 116(31):15463-15468.
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Masson GR, Burke JE, Ahn NG, Anand GS, Borchers C, Brier S, Bou-Assaf GM, Engen JR, Englander SW, Faber J, Garlish R, Griffin PR, Gross ML, Guttman M, Hamuro Y, Heck AJR, Houde D, Iacob RE, J?rgensen TJD, Kaltashov IA, Klinman JP, Konermann L, Man P, Mayne L, Pascal BD, Reichmann D, Skehel M, Snijder J, Strutzenberg TS, Underbakke ES, Wagner C, Wales TE, Walters BT, Weis DD, Wilson DJ, Wintrode PL, Zhang Z, Zheng J, Schriemer DC, Rand KD. Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. Nat Methods. 2019 07; 16(7):595-602.
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Rimmer MA, Nadeau OW, Yang J, Artigues A, Zhang Y, Carlson GM. The structure of the large regulatory a subunit of phosphorylase kinase examined by modeling and hydrogen-deuterium exchange. Protein Sci. 2018 02; 27(2):472-484.
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Ratzloff MW, Wilker MB, Mulder DW, Lubner CE, Hamby H, Brown KA, Dukovic G, King PW. Activation Thermodynamics and H/D Kinetic Isotope Effect of the Hox to HredH+ Transition in [FeFe] Hydrogenase. J Am Chem Soc. 2017 09 20; 139(37):12879-12882.
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Treuheit NA, Redhair M, Kwon H, McClary WD, Guttman M, Sumida JP, Atkins WM. Membrane Interactions, Ligand-Dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs. Biochemistry. 2016 Feb 23; 55(7):1058-69.
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Artigues A, Nadeau OW, Rimmer MA, Villar MT, Du X, Fenton AW, Carlson GM. Protein Structural Analysis via Mass Spectrometry-Based Proteomics. Adv Exp Med Biol. 2016; 919:397-431.
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Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Sci Signal. 2013 Aug 27; 6(290):ra76.
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Purna Chander C, Raju G, Mathai G, Srinivas R, Gaikwad HK, Bantu R, Nagarapu L. Electrospray ionization tandem mass spectrometry of 3-phenyl-N-(3-(4-phenylpiperazin-1-yl)propyl)-1H-pyrazole-5-carboxamide derivatives: unusual fragmentation involving loss of 11 u. Rapid Commun Mass Spectrom. 2012 Jan 30; 26(2):207-14.
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Oyeyemi OA, Sours KM, Lee T, Kohen A, Resing KA, Ahn NG, Klinman JP. Comparative hydrogen-deuterium exchange for a mesophilic vs thermophilic dihydrofolate reductase at 25 ?C: identification of a single active site region with enhanced flexibility in the mesophilic protein. Biochemistry. 2011 Sep 27; 50(38):8251-60.
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