Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Barbara Frederick

Concepts (193)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Head and Neck Neoplasms
11
2020
569
1.220
Why?
Poly(ADP-ribose) Polymerase Inhibitors
2
2020
137
0.700
Why?
Cetuximab
2
2020
111
0.660
Why?
Phthalazines
2
2020
63
0.650
Why?
Poly (ADP-Ribose) Polymerase-1
1
2020
55
0.620
Why?
Chemotherapy, Adjuvant
1
2020
429
0.580
Why?
Neoplasm Proteins
2
2020
445
0.580
Why?
DNA Repair
2
2020
256
0.570
Why?
Piperazines
2
2020
375
0.570
Why?
Quinazolines
3
2007
266
0.490
Why?
Carcinoma, Squamous Cell
6
2014
648
0.480
Why?
ErbB Receptors
5
2020
638
0.430
Why?
Protein Synthesis Inhibitors
2
2025
48
0.370
Why?
Xenograft Model Antitumor Assays
9
2025
939
0.310
Why?
Peptides, Cyclic
3
2020
273
0.310
Why?
Mice, Nude
7
2020
680
0.300
Why?
Receptors, Vascular Endothelial Growth Factor
2
2007
109
0.290
Why?
Cell Line, Tumor
12
2025
3565
0.280
Why?
Piperidines
2
2007
224
0.260
Why?
Smad4 Protein
2
2020
34
0.240
Why?
Mesoderm
1
2007
147
0.240
Why?
Protein Biosynthesis
4
2025
452
0.230
Why?
Combined Modality Therapy
5
2020
1281
0.220
Why?
Neovascularization, Pathologic
1
2006
287
0.200
Why?
Angiogenesis Inhibitors
1
2006
239
0.200
Why?
Neoplasms
4
2023
2946
0.200
Why?
Hematologic Neoplasms
1
2025
169
0.190
Why?
Drug Resistance, Neoplasm
1
2007
889
0.170
Why?
Carcinoma, Non-Small-Cell Lung
2
2008
1195
0.170
Why?
High-Throughput Screening Assays
1
2023
178
0.160
Why?
Epithelial Cells
1
2007
1141
0.160
Why?
DNA End-Joining Repair
1
2020
22
0.160
Why?
Proof of Concept Study
1
2020
90
0.160
Why?
Apoptosis
5
2025
2454
0.160
Why?
Clone Cells
1
2020
263
0.160
Why?
DNA, Neoplasm
1
2020
163
0.160
Why?
Drug Synergism
1
2020
355
0.150
Why?
Drosophila melanogaster
2
2012
241
0.150
Why?
Prostatic Neoplasms
3
2013
986
0.140
Why?
Cisplatin
1
2020
347
0.140
Why?
Antineoplastic Agents
3
2025
2231
0.140
Why?
Mice
10
2025
18493
0.130
Why?
Radiation, Ionizing
3
2012
86
0.130
Why?
Lung Neoplasms
2
2008
2679
0.130
Why?
Animals
15
2025
38417
0.120
Why?
DNA Damage
3
2020
440
0.120
Why?
Gene Expression Regulation, Neoplastic
2
2020
1457
0.120
Why?
Neoplastic Stem Cells
1
2020
409
0.110
Why?
Radiation-Sensitizing Agents
1
2015
43
0.110
Why?
N-Glycosyl Hydrolases
2
2004
6
0.100
Why?
Stromal Cells
1
2014
123
0.100
Why?
Radiation Tolerance
1
2014
103
0.100
Why?
Adherens Junctions
1
2013
24
0.100
Why?
Drug Screening Assays, Antitumor
2
2012
194
0.100
Why?
Hedgehog Proteins
1
2014
201
0.100
Why?
Plant Proteins
2
2004
111
0.100
Why?
Signal Transduction
6
2014
5272
0.090
Why?
Radiation-Protective Agents
1
2012
17
0.090
Why?
Sulfones
1
2013
127
0.090
Why?
Exosomes
1
2013
104
0.090
Why?
Prostate
1
2013
160
0.090
Why?
Metalloporphyrins
1
2012
63
0.090
Why?
Glycine
1
2013
186
0.090
Why?
Radiotherapy
1
2012
210
0.080
Why?
Autocrine Communication
1
2011
38
0.080
Why?
Stilbenes
1
2011
30
0.080
Why?
Maytansine
1
2011
18
0.080
Why?
Disease Models, Animal
2
2020
4605
0.080
Why?
Receptors, Fibroblast Growth Factor
1
2011
71
0.080
Why?
Paclitaxel
1
2012
261
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2020
2001
0.080
Why?
Neoplasm Invasiveness
2
2013
512
0.080
Why?
Prostaglandin D2
1
2009
21
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
2
2007
87
0.070
Why?
Oligonucleotide Array Sequence Analysis
2
2009
751
0.070
Why?
Antioxidants
1
2012
550
0.070
Why?
ATP-Binding Cassette Transporters
1
2009
117
0.070
Why?
Up-Regulation
2
2014
848
0.070
Why?
Humans
20
2025
147306
0.070
Why?
Antineoplastic Agents, Phytogenic
2
2011
178
0.060
Why?
Cell Proliferation
3
2025
2529
0.060
Why?
Receptors, LHRH
2
2004
14
0.060
Why?
Glutathione
1
2009
370
0.060
Why?
Cortactin
1
2006
7
0.060
Why?
Actin-Related Protein 2-3 Complex
1
2006
8
0.060
Why?
Chromosomes, Human, Pair 11
1
2006
60
0.060
Why?
Respiratory Mucosa
1
2009
324
0.060
Why?
Hypoxia
1
2013
1209
0.060
Why?
Cell Division
1
2007
758
0.060
Why?
Diagnostic Imaging
1
2008
342
0.060
Why?
Recombinant Fusion Proteins
2
2008
669
0.060
Why?
Drug Delivery Systems
2
2008
381
0.050
Why?
Proto-Oncogene Proteins c-myc
1
2025
169
0.050
Why?
Immunotoxins
1
2004
55
0.050
Why?
Cell Cycle
2
2020
600
0.050
Why?
Female
5
2020
80081
0.040
Why?
Gonadotropin-Releasing Hormone
1
2003
217
0.040
Why?
Drug Discovery
1
2023
153
0.040
Why?
Protein Kinase Inhibitors
1
2008
984
0.040
Why?
Carcinoma
1
2003
231
0.040
Why?
Phosphorylation
1
2025
1721
0.040
Why?
Mutation
4
2013
4130
0.040
Why?
Peptide Chain Elongation, Translational
1
2020
18
0.040
Why?
HCT116 Cells
2
2011
76
0.040
Why?
Dose-Response Relationship, Radiation
1
2020
141
0.040
Why?
Radiotherapy Dosage
1
2020
289
0.040
Why?
Tumor Cells, Cultured
1
2020
891
0.030
Why?
Chemoradiotherapy
1
2020
239
0.030
Why?
Cell Line
1
2023
2832
0.030
Why?
Transfection
2
2011
930
0.030
Why?
Veratrum Alkaloids
1
2014
20
0.030
Why?
Zinc Finger Protein GLI1
1
2014
25
0.030
Why?
Reproducibility of Results
1
2023
3448
0.030
Why?
Ribosomal Protein S6 Kinases, 70-kDa
1
2014
36
0.030
Why?
Cell Survival
2
2011
1111
0.030
Why?
Ribosome Inactivating Proteins, Type 1
2
2004
3
0.030
Why?
Tetraspanins
1
2013
19
0.030
Why?
Annexin A2
1
2013
15
0.030
Why?
HeLa Cells
1
2015
633
0.030
Why?
Metalloproteases
1
2013
42
0.020
Why?
CHO Cells
2
2004
169
0.020
Why?
Cricetinae
2
2004
305
0.020
Why?
Coculture Techniques
1
2013
247
0.020
Why?
Blotting, Western
2
2007
1186
0.020
Why?
Models, Biological
2
2012
1772
0.020
Why?
Heat-Shock Proteins
1
2013
140
0.020
Why?
Neoplasm Recurrence, Local
1
2020
1166
0.020
Why?
Cell Hypoxia
1
2013
249
0.020
Why?
Class I Phosphatidylinositol 3-Kinases
1
2013
108
0.020
Why?
Papillomaviridae
1
2013
116
0.020
Why?
Epithelial-Mesenchymal Transition
1
2014
222
0.020
Why?
Penis
1
2012
36
0.020
Why?
Erectile Dysfunction
1
2012
38
0.020
Why?
Testis
1
2012
165
0.020
Why?
Comet Assay
1
2011
14
0.020
Why?
Phosphatidylinositol 3-Kinases
1
2013
383
0.020
Why?
TOR Serine-Threonine Kinases
1
2014
456
0.020
Why?
Prognosis
1
2020
4384
0.020
Why?
BRCA1 Protein
1
2011
83
0.020
Why?
Fibroblast Growth Factor 2
1
2011
94
0.020
Why?
Immunoblotting
1
2011
296
0.020
Why?
Glioma
1
2015
432
0.020
Why?
Spindle Apparatus
1
2011
95
0.020
Why?
Cells, Cultured
2
2011
4170
0.020
Why?
Larva
1
2011
242
0.020
Why?
Mitosis
1
2011
194
0.020
Why?
Proto-Oncogene Proteins
1
2013
627
0.020
Why?
tert-Butylhydroperoxide
1
2009
9
0.020
Why?
Cell Death
1
2011
383
0.020
Why?
Cytoprotection
1
2009
56
0.020
Why?
Cell Cycle Proteins
1
2013
633
0.020
Why?
Cell Movement
1
2013
966
0.020
Why?
Papillomavirus Infections
1
2013
345
0.020
Why?
Proteome
1
2013
520
0.020
Why?
Src Homology 2 Domain-Containing, Transforming Protein 1
1
2008
10
0.020
Why?
Shc Signaling Adaptor Proteins
1
2008
10
0.020
Why?
GRB2 Adaptor Protein
1
2008
12
0.020
Why?
Substrate Specificity
1
2009
387
0.020
Why?
Biological Products
1
2012
258
0.020
Why?
Luciferases
1
2008
155
0.020
Why?
Protein-Tyrosine Kinases
1
2011
432
0.020
Why?
Benzimidazoles
1
2009
190
0.020
Why?
Survival Analysis
1
2011
1386
0.020
Why?
Genes, Reporter
1
2008
278
0.020
Why?
Skin
1
2012
759
0.020
Why?
Immunohistochemistry
1
2011
1730
0.020
Why?
Chromatography, High Pressure Liquid
1
2009
593
0.020
Why?
Tumor Suppressor Protein p53
1
2011
536
0.020
Why?
Rats, Sprague-Dawley
1
2012
2542
0.020
Why?
Enzyme Activation
1
2008
762
0.020
Why?
Neoplasm Transplantation
1
2007
246
0.020
Why?
Transcription Factors
1
2014
1747
0.010
Why?
Gene Amplification
1
2006
118
0.010
Why?
Brain Neoplasms
1
2015
1338
0.010
Why?
Histones
1
2011
672
0.010
Why?
In Situ Hybridization, Fluorescence
1
2006
330
0.010
Why?
Adaptor Proteins, Signal Transducing
1
2008
430
0.010
Why?
Chromosome Mapping
1
2006
512
0.010
Why?
Colony-Forming Units Assay
1
2004
95
0.010
Why?
Mice, Inbred BALB C
1
2007
1266
0.010
Why?
Actins
1
2006
428
0.010
Why?
Tumor Stem Cell Assay
1
2003
34
0.010
Why?
Rats
1
2012
5613
0.010
Why?
Pituitary Gland
1
2004
149
0.010
Why?
Male
4
2013
73954
0.010
Why?
Oxidative Stress
1
2009
1368
0.010
Why?
Drug Combinations
1
2003
399
0.010
Why?
Cattle
1
2004
948
0.010
Why?
Cell Membrane
1
2004
711
0.010
Why?
Feasibility Studies
1
2003
1147
0.010
Why?
Protein Binding
1
2004
2249
0.010
Why?
RNA, Messenger
1
2003
2812
0.010
Why?
Treatment Outcome
1
2008
11947
0.010
Why?
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