 Spindle Apparatus
"Spindle Apparatus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microtubule structure that forms during CELL DIVISION. It consists of two SPINDLE POLES, and sets of MICROTUBULES that may include the astral microtubules, the polar microtubules, and the kinetochore microtubules.
| Descriptor ID |
D008941
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| MeSH Number(s) |
A11.284.430.214.190.750.820
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| Concept/Terms |
Meiotic Spindle Apparatus- Meiotic Spindle Apparatus
- Apparatus, Meiotic Spindle
- Spindle Apparatus, Meiotic
- Meiotic Spindle
- Meiotic Spindles
- Spindle, Meiotic
- Spindles, Meiotic
Mitotic Spindle Apparatus- Mitotic Spindle Apparatus
- Apparatus, Mitotic Spindle
- Mitotic Spindle
- Mitotic Spindles
- Spindle, Mitotic
- Spindles, Mitotic
- Spindle Apparatus, Mitotic
- Mitotic Apparatus
- Apparatus, Mitotic
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Below are MeSH descriptors whose meaning is more general than "Spindle Apparatus".
Below are MeSH descriptors whose meaning is more specific than "Spindle Apparatus".
This graph shows the total number of publications written about "Spindle Apparatus" by people in this website by year, and whether "Spindle Apparatus" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 1 | 1 | 2 | | 2001 | 5 | 2 | 7 | | 2002 | 0 | 2 | 2 | | 2003 | 3 | 0 | 3 | | 2004 | 3 | 1 | 4 | | 2005 | 4 | 0 | 4 | | 2006 | 1 | 3 | 4 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 2 | 4 | | 2009 | 2 | 2 | 4 | | 2010 | 2 | 2 | 4 | | 2011 | 2 | 2 | 4 | | 2012 | 0 | 2 | 2 | | 2013 | 3 | 2 | 5 | | 2014 | 4 | 2 | 6 | | 2015 | 3 | 1 | 4 | | 2016 | 0 | 3 | 3 | | 2017 | 3 | 2 | 5 | | 2019 | 2 | 2 | 4 | | 2020 | 2 | 2 | 4 | | 2021 | 0 | 2 | 2 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 2 | 0 | 2 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spindle Apparatus" by people in Profiles.
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Steckhahn D, Fiorenza SA, Tai E, Forth S, Kramer PR, Betterton M. PRC1 resists microtubule sliding in two distinct resistive modes due to variations in the separation between overlapping microtubules. Mol Biol Cell. 2025 Oct 01; 36(10):ar115.
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Thomas EC, Moore JK. Selective regulation of kinesin-5 function by ?-tubulin carboxy-terminal tails. J Cell Biol. 2025 Mar 03; 224(3).
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Jones MH, Gergely ZR, Steckhahn D, Zhou B, Betterton MD. Kinesin-5/Cut7 C-terminal tail phosphorylation is essential for microtubule sliding force and bipolar mitotic spindle assembly. Curr Biol. 2024 Oct 21; 34(20):4781-4793.e6.
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Gergely ZR, Jones MH, Zhou B, Cash C, McIntosh JR, Betterton MD. Distinct regions of the kinesin-5 C-terminal tail are essential for mitotic spindle midzone localization and sliding force. Proc Natl Acad Sci U S A. 2023 09 26; 120(39):e2306480120.
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Gergely ZR, Ansari S, Jones MH, Zhou B, Cash C, McIntosh R, Betterton MD. The kinesin-5 protein Cut7 moves bidirectionally on fission yeast spindles with activity that increases in anaphase. J Cell Sci. 2023 03 01; 136(5).
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Ogren A, Parmar S, Mukherjee S, Gonzalez SJ, Plooster M, McClellan M, Mannava AG, Davidson E, Davis TN, Gardner MK. Kinesin-14 motors participate in a force balance at microtubule plus-ends to regulate dynamic instability. Proc Natl Acad Sci U S A. 2022 02 22; 119(8).
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Chan DCH, Xu J, Vujovic A, Wong N, Gordon V, de Rooij LPMH, Moreira S, Joyce CE, La Rose J, Sand? MJ, Doble BW, Novina CD, Rottapel RK, Hope KJ. Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis. Blood Adv. 2021 08 24; 5(16):3120-3133.
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Henen MA, Myers W, Schmitt LR, Wade KJ, Born A, Nichols PJ, V?geli B. The Disordered Spindly C-terminus Interacts with RZZ Subunits ROD-1 and ZWL-1 in the Kinetochore through the Same Sites in C. Elegans. J Mol Biol. 2021 02 19; 433(4):166812.
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Thomas EC, Ismael A, Moore JK. Ase1 domains dynamically slow anaphase spindle elongation and recruit Bim1 to the midzone. Mol Biol Cell. 2020 11 15; 31(24):2733-2747.
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Allen RJ, Guillen-Guio B, Oldham JM, Ma SF, Dressen A, Paynton ML, Kraven LM, Obeidat M, Li X, Ng M, Braybrooke R, Molina-Molina M, Hobbs BD, Putman RK, Sakornsakolpat P, Booth HL, Fahy WA, Hart SP, Hill MR, Hirani N, Hubbard RB, McAnulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Whyte MKB, Zhang Y, Kaminski N, Adegunsoye A, Strek ME, Neighbors M, Sheng XR, Gudmundsson G, Gudnason V, Hatabu H, Lederer DJ, Manichaikul A, Newell JD, O'Connor GT, Ortega VE, Xu H, Fingerlin TE, Boss? Y, Hao K, Joubert P, Nickle DC, Sin DD, Timens W, Furniss D, Morris AP, Zondervan KT, Hall IP, Sayers I, Tobin MD, Maher TM, Cho MH, Hunninghake GM, Schwartz DA, Yaspan BL, Molyneaux PL, Flores C, Noth I, Jenkins RG, Wain LV. Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2020 03 01; 201(5):564-574.
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