 Receptors, LHRH
"Receptors, LHRH" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors with a 6-kDa protein on the surfaces of cells that secrete LUTEINIZING HORMONE or FOLLICLE STIMULATING HORMONE, usually in the adenohypophysis. LUTEINIZING HORMONE-RELEASING HORMONE binds to these receptors, is endocytosed with the receptor and, in the cell, triggers the release of LUTEINIZING HORMONE or FOLLICLE STIMULATING HORMONE by the cell. These receptors are also found in rat gonads. INHIBINS prevent the binding of GnRH to its receptors.
| Descriptor ID |
D011966
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| MeSH Number(s) |
D12.776.543.750.695.410 D12.776.543.750.720.600.460 D12.776.543.750.750.555.460 D12.776.543.750.750.700.460
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| Concept/Terms |
Receptors, LHRH- Receptors, LHRH
- Receptors, Gonadorelin
- Gonadotropin-Releasing Hormone Receptor
- Gonadotropin Releasing Hormone Receptor
- Hormone Receptor, Gonadotropin-Releasing
- Receptor, Gonadotropin-Releasing Hormone
- Gonadotropin Releasing-Hormone Receptors
- Gonadotropin Releasing Hormone Receptors
- Receptors, LHFSHRH
- LHFSHRH Receptors
- LHRH Receptor
- Receptor, LHRH
- LHRH Receptors
- Luliberin Receptors
- Receptors, Luliberin
- Luteinizing Hormone Releasing Hormone Receptors
- Luteinizing Hormone Releasing-Hormone Receptor
- Luteinizing Hormone Releasing Hormone Receptor
- GnRH Receptor
- Receptor, GnRH
- GnRH Receptors
- Receptors, GnRH
- Gonadoliberin Receptors
- Receptors, Gonadoliberin
- Gonadorelin Receptor
- Receptor, Gonadorelin
- Gonadorelin Receptors
- Follicle Stimulating Hormone-Releasing Hormone Receptors
- Follicle Stimulating Hormone Releasing Hormone Receptors
- Receptors, Gonadotropin Releasing-Hormone
- Receptors, Gonadotropin Releasing Hormone
- Releasing-Hormone Receptors, Gonadotropin
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Below are MeSH descriptors whose meaning is more general than "Receptors, LHRH".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, LHRH [D12.776.543.750.695.410]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, LHRH [D12.776.543.750.720.600.460]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, LHRH [D12.776.543.750.750.555.460]
- Receptors, Pituitary Hormone-Regulating Hormone [D12.776.543.750.750.700]
- Receptors, LHRH [D12.776.543.750.750.700.460]
Below are MeSH descriptors whose meaning is more specific than "Receptors, LHRH".
This graph shows the total number of publications written about "Receptors, LHRH" by people in this website by year, and whether "Receptors, LHRH" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 2 | 3 | | 2004 | 3 | 0 | 3 | | 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, LHRH" by people in Profiles.
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Crawford ED, Schally AV, Pinthus JH, Block NL, Rick FG, Garnick MB, Eckel RH, Keane TE, Shore ND, Dahdal DN, Beveridge TJR, Marshall DC. The potential role of follicle-stimulating hormone in the cardiovascular, metabolic, skeletal, and cognitive effects associated with androgen deprivation therapy. Urol Oncol. 2017 05; 35(5):183-191.
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Kavanaugh SI, Tsai PS. Functional Authentication of a Novel Gastropod Gonadotropin-Releasing Hormone Receptor Reveals Unusual Features and Evolutionary Insight. PLoS One. 2016; 11(7):e0160292.
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Kadokawa H, Pandey K, Nahar A, Nakamura U, Rudolf FO. Gonadotropin-releasing hormone (GnRH) receptors of cattle aggregate on the surface of gonadotrophs and are increased by elevated GnRH concentrations. Anim Reprod Sci. 2014 Nov 30; 150(3-4):84-95.
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Lu J, Hathaway HJ, Royce ME, Prossnitz ER, Miao Y. Introduction of D-phenylalanine enhanced the receptor binding affinities of gonadotropin-releasing hormone peptides. Bioorg Med Chem Lett. 2014 Feb 01; 24(3):725-30.
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Guo H, Hathaway H, Royce ME, Prossnitz ER, Miao Y. Influences of hydrocarbon linkers on the receptor binding affinities of gonadotropin-releasing hormone peptides. Bioorg Med Chem Lett. 2013 Oct 15; 23(20):5484-7.
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Rochester JR, Chung WC, Hayes TB, Tsai PS. Opposite-sex housing reactivates the declining GnRH system in aged transgenic male mice with FGF signaling deficiency. Am J Physiol Endocrinol Metab. 2012 Dec 15; 303(12):E1428-39.
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Sun B, Kavanaugh SI, Tsai PS. Gonadotropin-releasing hormone in protostomes: insights from functional studies on Aplysia californica. Gen Comp Endocrinol. 2012 May 01; 176(3):321-6.
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Guo H, Lu J, Hathaway H, Royce ME, Prossnitz ER, Miao Y. Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides. Bioconjug Chem. 2011 Aug 17; 22(8):1682-9.
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Sundaram S, Durairaj C, Kadam R, Kompella UB. Luteinizing hormone-releasing hormone receptor-targeted deslorelin-docetaxel conjugate enhances efficacy of docetaxel in prostate cancer therapy. Mol Cancer Ther. 2009 Jun; 8(6):1655-65.
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Sundaram S, Roy SK, Kompella UB. Differential expression of LHRH-receptor in bovine nasal tissue and its role in deslorelin delivery. Peptides. 2009 Feb; 30(2):351-8.
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