 Peptide Chain Elongation, Translational
"Peptide Chain Elongation, Translational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process of GENETIC TRANSLATION, when an amino acid is transferred from its cognate TRANSFER RNA to the lengthening chain of PEPTIDES.
| Descriptor ID |
D010441
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| MeSH Number(s) |
G02.111.660.871.640 G03.734.871.640
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| Concept/Terms |
Peptide Chain Elongation, Translational- Peptide Chain Elongation, Translational
- Translational Peptide Chain Elongation
- Protein Chain Elongation, Translational
- Protein Translation Elongation
- Translation Elongation, Protein
- Elongation, Protein Translation
- Translational Elongation, Protein
- Elongation, Protein Translational
- Protein Translational Elongation
- Protein Biosynthesis Elongation
- Biosynthesis Elongation, Protein
- Elongation, Protein Biosynthesis
- Chain Elongation, Peptide, Translational
- Translation Elongation, Genetic
- Elongation, Genetic Translation
- Genetic Translation Elongation
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Below are MeSH descriptors whose meaning is more general than "Peptide Chain Elongation, Translational".
Below are MeSH descriptors whose meaning is more specific than "Peptide Chain Elongation, Translational".
This graph shows the total number of publications written about "Peptide Chain Elongation, Translational" by people in this website by year, and whether "Peptide Chain Elongation, Translational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Peptide Chain Elongation, Translational" by people in Profiles.
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Hobson BD, Kong L, Hartwick EW, Gonzalez RL, Sims PA. Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes. Elife. 2020 08 26; 9.
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Keysar SB, Gomes N, Miller B, Jackson BC, Le PN, Morton JJ, Reisinger J, Chimed TS, Gomez KE, Nieto C, Frederick B, Pronk GJ, Somerset HL, Tan AC, Wang XJ, Raben D, Su TT, Jimeno A. Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma. Cancer Res. 2020 03 01; 80(5):1183-1198.
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Hussmann JA, Patchett S, Johnson A, Sawyer S, Press WH. Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast. PLoS Genet. 2015 Dec; 11(12):e1005732.
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Zaccara S, Tebaldi T, Pederiva C, Ciribilli Y, Bisio A, Inga A. p53-directed translational control can shape and expand the universe of p53 target genes. Cell Death Differ. 2014 Oct; 21(10):1522-34.
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Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Nat Struct Mol Biol. 2013 Feb; 20(2):150-8.
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Perraud AL, Zhao X, Ryazanov AG, Schmitz C. The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k. Cell Signal. 2011 Mar; 23(3):586-93.
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Ramirez-Aguilar KA, Kuchta RD. Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry. 2004 Feb 17; 43(6):1754-62.
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Carnes J, Jacobson M, Leinwand L, Yarus M. Stop codon suppression via inhibition of eRF1 expression. RNA. 2003 Jun; 9(6):648-53.
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Barton DJ, Morasco BJ, Flanegan JB. Translating ribosomes inhibit poliovirus negative-strand RNA synthesis. J Virol. 1999 Dec; 73(12):10104-12.
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Kirk BW, Kuchta RD. Human DNA primase: anion inhibition, manganese stimulation, and their effects on in vitro start-site selection. Biochemistry. 1999 Aug 03; 38(31):10126-34.
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