 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.679 G03.808
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 6 | 6 | | 1994 | 0 | 11 | 11 | | 1995 | 0 | 10 | 10 | | 1996 | 0 | 20 | 20 | | 1997 | 1 | 15 | 16 | | 1998 | 0 | 22 | 22 | | 1999 | 0 | 14 | 14 | | 2000 | 0 | 40 | 40 | | 2001 | 0 | 26 | 26 | | 2002 | 0 | 43 | 43 | | 2003 | 0 | 43 | 43 | | 2004 | 1 | 59 | 60 | | 2005 | 0 | 55 | 55 | | 2006 | 0 | 67 | 67 | | 2007 | 0 | 56 | 56 | | 2008 | 1 | 56 | 57 | | 2009 | 0 | 63 | 63 | | 2010 | 0 | 73 | 73 | | 2011 | 1 | 86 | 87 | | 2012 | 0 | 79 | 79 | | 2013 | 2 | 82 | 84 | | 2014 | 0 | 67 | 67 | | 2015 | 1 | 58 | 59 | | 2016 | 0 | 85 | 85 | | 2017 | 0 | 82 | 82 | | 2018 | 2 | 64 | 66 | | 2019 | 0 | 59 | 59 | | 2020 | 0 | 65 | 65 | | 2021 | 3 | 32 | 35 | | 2022 | 0 | 17 | 17 | | 2023 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Black JC, Kutateladze TG. Atypical histone targets of PHD fingers. J Biol Chem. 2023 04; 299(4):104601.
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Plonski AP, Reed SM. Assessing protein homology models with docking reproducibility. J Mol Graph Model. 2023 Jun; 121:108430.
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Chiu TP, Rao S, Rohs R. Physicochemical models of protein-DNA binding with standard and modified base pairs. Proc Natl Acad Sci U S A. 2023 01 24; 120(4):e2205796120.
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Singh A, Miller RC, Archuleta SR, Kugel JF. Evaluating two steps in transcription using a fluorescence-based electrophoretic mobility shift assay. Biochem Mol Biol Educ. 2023 03; 51(2):230-235.
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Fleming IR, Hannan JP, Swisher GH, Tesdahl CD, Martyr JG, Cordaro NJ, Erbse AH, Falke JJ. Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements. Anal Biochem. 2023 02 15; 663:115019.
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Wieser TA, Wuttke DS. Replication Protein A Utilizes Differential Engagement of Its DNA-Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes. Biochemistry. 2022 Nov 15; 61(22):2592-2606.
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Steiner HR, Lammer NC, Batey RT, Wuttke DS. An Extended DNA Binding Domain of the Estrogen Receptor Alpha Directly Interacts with RNAs in Vitro. Biochemistry. 2022 Nov 15; 61(22):2490-2494.
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Born A, Soetbeer J, Henen MA, Breitgoff F, Polyhach Y, Jeschke G, V?geli B. Ligand-specific conformational change drives interdomain allostery in Pin1. Nat Commun. 2022 08 04; 13(1):4546.
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Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, Roberts RC, Huttner A, Kleinman JE, Hyde TM, Straub RE, Walsh CA, Urban AE, Leckman JF, Weinberger DR, Vaccarino FM, Abyzov A. Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science. 2022 07 29; 377(6605):511-517.
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Striepen JF, Voeltz GK. Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission. J Cell Biol. 2022 08 01; 221(8).
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