 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.679 G03.808
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 9 | 9 | | 1996 | 0 | 17 | 17 | | 1997 | 1 | 15 | 16 | | 1998 | 0 | 22 | 22 | | 1999 | 0 | 13 | 13 | | 2000 | 0 | 28 | 28 | | 2001 | 0 | 36 | 36 | | 2002 | 0 | 49 | 49 | | 2003 | 0 | 38 | 38 | | 2004 | 1 | 47 | 48 | | 2005 | 0 | 60 | 60 | | 2006 | 0 | 64 | 64 | | 2007 | 0 | 53 | 53 | | 2008 | 1 | 58 | 59 | | 2009 | 0 | 62 | 62 | | 2010 | 0 | 65 | 65 | | 2011 | 1 | 86 | 87 | | 2012 | 0 | 88 | 88 | | 2013 | 2 | 81 | 83 | | 2014 | 0 | 64 | 64 | | 2015 | 2 | 62 | 64 | | 2016 | 0 | 86 | 86 | | 2017 | 0 | 70 | 70 | | 2018 | 3 | 60 | 63 | | 2019 | 0 | 65 | 65 | | 2020 | 0 | 62 | 62 | | 2021 | 2 | 34 | 36 | | 2022 | 0 | 19 | 19 | | 2023 | 0 | 16 | 16 | | 2024 | 10 | 34 | 44 | | 2025 | 0 | 22 | 22 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Gaurav N, O'Hara R, Hyder U, Qin W, Her C, Romero H, Kumar A, Marcaida MJ, Singh RK, Hovius R, Selvam K, Liu J, Martire S, Yao Y, Challa A, Dal Peraro M, Fierz B, Kono H, Cardoso MC, Debelouchina GT, Leonhardt H, D'Orso I, Banaszynski LA, Kutateladze TG. The HP1 box of KAP1 organizes HP1a for silencing of endogenous retroviral elements in embryonic stem cells. Nat Commun. 2025 May 31; 16(1):5066.
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Duncalf L, Wang X, Aljabri AA, Campbell AE, Alharbi RQ, Donaldson I, Hayes A, Peti W, Page R, Bennett D. PNUTS:PP1 recruitment to Tox4 regulates chromosomal dispersal in Drosophila germline development. Cell Rep. 2025 May 27; 44(5):115693.
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Mahajan S, Kumar R, Singh A, Dhaka P, Pareek A, Kumar P, Tomar S. Targeting the host protein G3BP1 for the discovery of novel antiviral inhibitors against Chikungunya virus. Virology. 2025 Jul; 608:110551.
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Briganti L, Annamalai AS, Bester SM, Wei G, Andino-Moncada JR, Singh SP, Kleinpeter AB, Tripathi M, Nguyen B, Radhakrishnan R, Singh PK, Greenwood J, Schope LI, Haney R, Huang S-W, Freed EO, Engelman AN, Francis AC, Kvaratskhelia M. Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir. mBio. 2025 May 14; 16(5):e0361324.
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Lewis EM, Becker O, Symons AN, LaCoss C, Baclig AJ, Guzman A, Sanders C, Gonzalez L, Warner LR, Lewis KA. The LARP6 La module from Tetrabaena socialis reveals structural and functional differences from plant and animal LARP6 homologues. RNA Biol. 2025 Dec; 22(1):1-9.
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Schlinsog M, Sattasathuchana T, Xu P, Guidez EB, Gilson MK, Potter MJ, Gordon MS, Webb SP. Computation of Protein-Ligand Binding Free Energies with a Quantum Mechanics-Based Mining Minima Algorithm. J Chem Theory Comput. 2025 Apr 22; 21(8):4236-4265.
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Sampath R, Vaeth K, Mikalayeva V, Skeberdis VA, Prekeris R, Han KJ. Rab40 GTPases regulate AMBRA1-mediated transcription and cell migration. J Cell Sci. 2025 Apr 01; 138(7).
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Lietzke EE, Saeb D, Aldrich EC, Bruce KD, Sprenger KG. Synergistic reduction in interfacial flexibility of TREM2R47H and ApoE4 may underlie AD pathology. Alzheimers Dement. 2025 Apr; 21(4):e70120.
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Perni S, Polster A, Beam KG. Interaction between CaV2.1 and Junctophilin3/4 depends on the II-III loop of CaV2.1 and on the a-helical region of Junctophilin3/4. J Biol Chem. 2025 Apr; 301(4):108424.
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Brown CN, Blaine RE, Barker CM, Coultrap SJ, Bayer KU. The neuroprotective ?-hydroxybutyrate analog 3-hydroxycyclopent-1-enecarboxylic acid does not directly affect CaMKIIa autophosphorylation at T286 or binding to GluN2B. Mol Pharmacol. 2025 Apr; 107(4):100029.
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