Genetic Load
"Genetic Load" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relative amount by which the average fitness of a POPULATION is lowered, due to the presence of GENES that decrease survival, compared to the GENOTYPE with maximum or optimal fitness. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D040741
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| MeSH Number(s) |
G05.350
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Genetic Load".
Below are MeSH descriptors whose meaning is more specific than "Genetic Load".
This graph shows the total number of publications written about "Genetic Load" by people in this website by year, and whether "Genetic Load" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genetic Load" by people in Profiles.
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Wilder AP, Shier DM, King SND, Dudchenko O, Funk ER, Misuraca A, Houck ML, Miller WB, Curry CJ, Fronczek J, Khan R, Weisz D, Fisher RN, Lieberman Aiden E, Ryder OA, Steiner CC. Fitness benefits of genetic rescue despite chromosomal differences in an endangered pocket mouse. Science. 2025 Aug 21; 389(6762):835-839.
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Peterson ML, Kay KM. Mating system plasticity promotes persistence and adaptation of colonizing populations of hermaphroditic angiosperms. Am Nat. 2015 Jan; 185(1):28-43.
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Wise LA, Ruiz-Narvaez EA, Palmer JR, Cozier YC, Tandon A, Patterson N, Radin RG, Rosenberg L, Reich D. African ancestry and genetic risk for uterine leiomyomata. Am J Epidemiol. 2012 Dec 15; 176(12):1159-68.
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