 DNA Repair
"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
| Descriptor ID |
D004260
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| MeSH Number(s) |
G02.111.222 G05.219
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| Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
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Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 3 | 4 | | 2000 | 2 | 3 | 5 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 2 | 0 | 2 | | 2004 | 4 | 3 | 7 | | 2005 | 4 | 1 | 5 | | 2006 | 2 | 6 | 8 | | 2007 | 3 | 4 | 7 | | 2008 | 5 | 3 | 8 | | 2009 | 3 | 2 | 5 | | 2010 | 6 | 3 | 9 | | 2011 | 2 | 1 | 3 | | 2012 | 3 | 4 | 7 | | 2013 | 1 | 5 | 6 | | 2014 | 2 | 7 | 9 | | 2015 | 4 | 7 | 11 | | 2016 | 5 | 4 | 9 | | 2017 | 0 | 5 | 5 | | 2018 | 3 | 5 | 8 | | 2019 | 2 | 2 | 4 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Manickavinayaham S, Vélez-Cruz R, Biswas AK, Bedford E, Klein BJ, Kutateladze TG, Liu B, Bedford MT, Johnson DG. E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair. Nat Commun. 2019 10 30; 10(1):4951.
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Zatopek KM, Potapov V, Maduzia LL, Alpaslan E, Chen L, Evans TC, Ong JL, Ettwiller LM, Gardner AF. RADAR-seq: A RAre DAmage and Repair sequencing method for detecting DNA damage on a genome-wide scale. DNA Repair (Amst). 2019 08; 80:36-44.
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Hernandez AL, Young CD, Wang JH, Wang XJ. Lessons learned from SMAD4 loss in squamous cell carcinomas. Mol Carcinog. 2019 09; 58(9):1648-1655.
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Estrem C, Moore JK. Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast. Mol Biol Cell. 2019 07 22; 30(16):2000-2013.
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Pérez Di Giorgio JA, Lepage É, Tremblay-Belzile S, Truche S, Loubert-Hudon A, Brisson N. Transcription is a major driving force for plastid genome instability in Arabidopsis. PLoS One. 2019; 14(4):e0214552.
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Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N. BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. EMBO Rep. 2018 12; 19(12).
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Cho RJ, Alexandrov LB, den Breems NY, Atanasova VS, Farshchian M, Purdom E, Nguyen TN, Coarfa C, Rajapakshe K, Prisco M, Sahu J, Tassone P, Greenawalt EJ, Collisson EA, Wu W, Yao H, Su X, Guttmann-Gruber C, Hofbauer JP, Hashmi R, Fuentes I, Benz SC, Golovato J, Ehli EA, Davis CM, Davies GE, Covington KR, Murrell DF, Salas-Alanis JC, Palisson F, Bruckner AL, Robinson W, Has C, Bruckner-Tuderman L, Titeux M, Jonkman MF, Rashidghamat E, Lwin SM, Mellerio JE, McGrath JA, Bauer JW, Hovnanian A, Tsai KY, South AP. APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2018 08 22; 10(455).
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Rudolph J, Mahadevan J, Dyer P, Luger K. Poly(ADP-ribose) polymerase 1 searches DNA via a 'monkey bar' mechanism. Elife. 2018 08 08; 7.
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Zhang Y, Kutateladze TG. Switching 53BP1 on and off via Tudors. Nat Struct Mol Biol. 2018 08; 25(8):646-647.
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Cartwright IM, Su C, Haskins JS, Salinas VA, Sunada S, Yu H, Uesaka M, Hirakawa H, Chen DJ, Fujimori A, Kato TA. DNA Repair Deficient Chinese Hamster Ovary Cells Exhibiting Differential Sensitivity to Charged Particle Radiation under Aerobic and Hypoxic Conditions. Int J Mol Sci. 2018 Jul 30; 19(8).
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