 DNA Repair
"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
| Descriptor ID |
D004260
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| MeSH Number(s) |
G02.111.222 G05.219
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| Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
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Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 3 | 4 | | 2000 | 2 | 3 | 5 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 2 | 0 | 2 | | 2004 | 4 | 3 | 7 | | 2005 | 4 | 2 | 6 | | 2006 | 2 | 6 | 8 | | 2007 | 3 | 4 | 7 | | 2008 | 5 | 3 | 8 | | 2009 | 3 | 2 | 5 | | 2010 | 5 | 4 | 9 | | 2011 | 2 | 2 | 4 | | 2012 | 1 | 5 | 6 | | 2013 | 1 | 4 | 5 | | 2014 | 2 | 5 | 7 | | 2015 | 4 | 6 | 10 | | 2016 | 4 | 4 | 8 | | 2017 | 0 | 7 | 7 | | 2018 | 3 | 5 | 8 | | 2019 | 4 | 2 | 6 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Richer AL, Riemondy KA, Hardie L, Hesselberth JR. Simultaneous measurement of biochemical phenotypes and gene expression in single cells. Nucleic Acids Res. 2020 06 04; 48(10):e59.
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Keysar SB, Gomes N, Miller B, Jackson BC, Le PN, Morton JJ, Reisinger J, Chimed TS, Gomez KE, Nieto C, Frederick B, Pronk GJ, Somerset HL, Tan AC, Wang XJ, Raben D, Su TT, Jimeno A. Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma. Cancer Res. 2020 03 01; 80(5):1183-1198.
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Manickavinayaham S, Vélez-Cruz R, Biswas AK, Bedford E, Klein BJ, Kutateladze TG, Liu B, Bedford MT, Johnson DG. E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair. Nat Commun. 2019 10 30; 10(1):4951.
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Mahadevan J, Bowerman S, Luger K. Quantitating repair protein accumulation at DNA lesions: Past, present, and future. DNA Repair (Amst). 2019 09; 81:102650.
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Zatopek KM, Potapov V, Maduzia LL, Alpaslan E, Chen L, Evans TC, Ong JL, Ettwiller LM, Gardner AF. RADAR-seq: A RAre DAmage and Repair sequencing method for detecting DNA damage on a genome-wide scale. DNA Repair (Amst). 2019 08; 80:36-44.
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Hernandez AL, Young CD, Wang JH, Wang XJ. Lessons learned from SMAD4 loss in squamous cell carcinomas. Mol Carcinog. 2019 09; 58(9):1648-1655.
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Estrem C, Moore JK. Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast. Mol Biol Cell. 2019 07 22; 30(16):2000-2013.
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Guard SE, Poss ZC, Ebmeier CC, Pagratis M, Simpson H, Taatjes DJ, Old WM. The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair. Sci Rep. 2019 04 25; 9(1):6539.
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Pérez Di Giorgio JA, Lepage É, Tremblay-Belzile S, Truche S, Loubert-Hudon A, Brisson N. Transcription is a major driving force for plastid genome instability in Arabidopsis. PLoS One. 2019; 14(4):e0214552.
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Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N. BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. . 2018 12; 19(12).
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