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Alessandra Brambati

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PHARM General Operations

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Jalan M, Brambati A, Shah H, McDermott N, Patel J, Zhu Y, Doymaz A, Wu J, Anderson KS, Gazzo A, Pareja F, Yamaguchi TN, Vougiouklakis T, Ahmed-Seghir S, Steinberg P, Neiman-Golden A, Azeroglu B, Gomez-Aguilar J, da Silva EM, Hussain S, Higginson D, Boutros PC, Riaz N, Reis-Filho JS, Powell SN, Sfeir A. RNA transcripts serve as a template for double-strand break repair in human cells. Nat Commun. 2025 May 10; 16(1):4349. PMID: 40348775.
      View in: PubMed
    2. Jalan M, Brambati A, Shah H, McDermott N, Patel J, Zhu Y, Doymaz A, Wu J, Anderson KS, Gazzo A, Pareja F, Yamaguchi TN, Vougiouklakis T, Ahmed-Seghir S, Steinberg P, Neiman-Golden A, Azeroglu B, Gomez-Aguilar J, da Silva EM, Hussain S, Higginson D, Boutros PC, Riaz N, Reis-Filho JS, Powell SN, Sfeir A. RNA Transcripts Serve as a Template for Double-Strand Break Repair in Human Cells. bioRxiv. 2025 Feb 25. PMID: 40060534.
      View in: PubMed
    3. Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. RHINO directs MMEJ to repair DNA breaks in mitosis. Science. 2023 08 11; 381(6658):653-660. PMID: 37440612.
      View in: PubMed
    4. Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. RHINO restricts MMEJ activity to mitosis. bioRxiv. 2023 Mar 16. PMID: 36993461.
      View in: PubMed
    5. Zardoni L, Nardini E, Brambati A, Lucca C, Choudhary R, Loperfido F, Sabbioneda S, Liberi G. Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions. Nucleic Acids Res. 2021 12 16; 49(22):12769-12784. PMID: 34878142.
      View in: PubMed
    6. Chandramouly G, Zhao J, McDevitt S, Rusanov T, Hoang T, Borisonnik N, Treddinick T, Lopezcolorado FW, Kent T, Siddique LA, Mallon J, Huhn J, Shoda Z, Kashkina E, Brambati A, Stark JM, Chen XS, Pomerantz RT. Pol? reverse transcribes RNA and promotes RNA-templated DNA repair. Sci Adv. 2021 06; 7(24). PMID: 34117057.
      View in: PubMed
    7. Rawal CC, Zardoni L, Di Terlizzi M, Galati E, Brambati A, Lazzaro F, Liberi G, Pellicioli A. Senataxin Ortholog Sen1 Limits DNA:RNA Hybrid Accumulation at DNA Double-Strand Breaks to Control End Resection and Repair Fidelity. Cell Rep. 2020 05 05; 31(5):107603. PMID: 32375052.
      View in: PubMed
    8. Brambati A, Barry RM, Sfeir A. DNA polymerase theta (Pol?) - an error-prone polymerase necessary for genome stability. Curr Opin Genet Dev. 2020 02; 60:119-126. PMID: 32302896.
      View in: PubMed
    9. Brambati A, Zardoni L, Nardini E, Pellicioli A, Liberi G. The dark side of RNA:DNA hybrids. Mutat Res Rev Mutat Res. 2020 Apr - Jun; 784:108300. PMID: 32430097.
      View in: PubMed
    10. Brambati A, Zardoni L, Achar YJ, Piccini D, Galanti L, Colosio A, Foiani M, Liberi G. Dormant origins and fork protection mechanisms rescue sister forks arrested by transcription. Nucleic Acids Res. 2018 02 16; 46(3):1227-1239. PMID: 29059325.
      View in: PubMed
    11. Brambati A, Colosio A, Zardoni L, Galanti L, Liberi G. Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability. Front Genet. 2015; 6:166. PMID: 25972894.
      View in: PubMed
    12. Alzu A, Bermejo R, Begnis M, Lucca C, Piccini D, Carotenuto W, Saponaro M, Brambati A, Cocito A, Foiani M, Liberi G. Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes. Cell. 2012 Nov 09; 151(4):835-846. PMID: 23141540.
      View in: PubMed
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