 Nuclear Receptor Subfamily 2, Group C, Member 2
"Nuclear Receptor Subfamily 2, Group C, Member 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
| Descriptor ID |
D057125
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| MeSH Number(s) |
D12.776.260.643.327 D12.776.826.209.327
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| Concept/Terms |
Nuclear Receptor Subfamily 2, Group C, Member 2- Nuclear Receptor Subfamily 2, Group C, Member 2
- TR4 Nuclear Hormone Receptor
- TAK1 Receptor
- Receptor, TAK1
- Testicular Receptor 4
- Nuclear Receptor NR2C2
- NR2C2, Nuclear Receptor
- Orphan Nuclear Receptor TR4
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 2, Group C, Member 2".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 2, Group C, Member 2".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 2, Group C, Member 2" by people in this website by year, and whether "Nuclear Receptor Subfamily 2, Group C, Member 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 2, Group C, Member 2" by people in Profiles.
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Xia L, Shen D, Zhang Y, Lu J, Wang M, Wang H, Chen Y, Xue D, Xie D, Li G. Targeting the TR4 nuclear receptor with antagonist bexarotene can suppress the proopiomelanocortin signalling in AtT-20 cells. J Cell Mol Med. 2021 03; 25(5):2404-2417.
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