S100 Proteins
"S100 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Descriptor ID |
D009418
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MeSH Number(s) |
D12.776.157.125.750 D12.776.631.655
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Concept/Terms |
S100 Proteins- S100 Proteins
- Nerve Tissue Protein S 100
- S100 Protein Family
- Antigen S 100
- S-100 Protein
- S 100 Protein
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Below are MeSH descriptors whose meaning is more general than "S100 Proteins".
Below are MeSH descriptors whose meaning is more specific than "S100 Proteins".
This graph shows the total number of publications written about "S100 Proteins" by people in this website by year, and whether "S100 Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2008 | 1 | 1 | 2 | 2009 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2013 | 0 | 2 | 2 | 2014 | 1 | 2 | 3 | 2015 | 0 | 2 | 2 | 2016 | 1 | 0 | 1 | 2017 | 1 | 1 | 2 | 2018 | 0 | 1 | 1 | 2020 | 1 | 1 | 2 | 2021 | 1 | 0 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "S100 Proteins" by people in Profiles.
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Saleem A, Narala S, Raghavan SS. Immunohistochemistry in melanocytic lesions: Updates with a practical review for pathologists. Semin Diagn Pathol. 2022 Jul; 39(4):239-247.
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Wheeler LC, Harms MJ. Were Ancestral Proteins Less Specific? Mol Biol Evol. 2021 05 19; 38(6):2227-2239.
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Wheeler LC, Perkins A, Wong CE, Harms MJ. Learning peptide recognition rules for a low-specificity protein. Protein Sci. 2020 11; 29(11):2259-2273.
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Li Y, Beizai P, Russell JW, Westbrook L, Nowain A, Wang HL. Mucosal Schwann cell hamartoma of the gastroesophageal junction: A series of 6 cases and comparison with colorectal counterpart. Ann Diagn Pathol. 2020 Aug; 47:151531.
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Tham EH, Dyjack N, Kim BE, Rios C, Seibold MA, Leung DYM, Goleva E. Expression and function of the ectopic olfactory receptor OR10G7 in patients with atopic dermatitis. J Allergy Clin Immunol. 2019 05; 143(5):1838-1848.e4.
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Wheeler LC, Anderson JA, Morrison AJ, Wong CE, Harms MJ. Conservation of Specificity in Two Low-Specificity Proteins. Biochemistry. 2018 02 06; 57(5):684-695.
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LaBerge GS, Duvall E, Grasmick Z, Haedicke K, Pawelek J. A Melanoma Lymph Node Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: A Second Case of Leucocyte-Tumor Cell Hybridization in Cancer Metastasis. PLoS One. 2017; 12(2):e0168581.
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Wheeler LC, Donor MT, Prell JS, Harms MJ. Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family. PLoS One. 2016; 11(10):e0164740.
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Myles IA, Zhao M, Nardone G, Olano LR, Reckhow JD, Saleem D, Break TJ, Lionakis MS, Myers TG, Gardina PJ, Kirkpatrick CH, Holland SM, Datta SK. CD8+ T cells produce a dialyzable antigen-specific activator of dendritic cells. J Leukoc Biol. 2017 01; 101(1):307-320.
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Torgerson DG, Giri T, Druley TE, Zheng J, Huntsman S, Seibold MA, Young AL, Schweiger T, Yin-Declue H, Sajol GD, Schechtman KB, Hernandez RD, Randolph AG, Bacharier LB, Castro M. Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy. PLoS One. 2015; 10(11):e0142649.
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