 GAP-43 Protein
"GAP-43 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
| Descriptor ID |
D019922
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| MeSH Number(s) |
D12.776.395.550.400 D12.776.543.550.400 D12.776.631.400
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| Concept/Terms |
GAP-43 Protein- GAP-43 Protein
- GAP 43 Protein
- Phosphoprotein B-50
- Phosphoprotein B 50
- GAP-43
- Neuromodulin
- Growth-Associated Protein 43
- Growth Associated Protein 43
- Phosphoprotein pp46
- B-50 Protein
- B 50 Protein
- GAP43 Protein
- Nerve Growth Cone Membrane Protein GAP-43
- Nerve Growth Cone Membrane Protein GAP 43
- Phosphoprotein F1
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Below are MeSH descriptors whose meaning is more general than "GAP-43 Protein".
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This graph shows the total number of publications written about "GAP-43 Protein" by people in this website by year, and whether "GAP-43 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "GAP-43 Protein" by people in Profiles.
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Ren T, Faust A, van der Merwe Y, Xiao B, Johnson S, Kandakatla A, Gorantla VS, Badylak SF, Washington KM, Steketee MB. Fetal extracellular matrix nerve wraps locally improve peripheral nerve remodeling after complete transection and direct repair in rat. Sci Rep. 2018 03 14; 8(1):4474.
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Tesic V, Perovic M, Zaletel I, Jovanovic M, Puskas N, Ruzdijic S, Kanazir S. A single high dose of dexamethasone increases GAP-43 and synaptophysin in the hippocampus of aged rats. Exp Gerontol. 2017 11; 98:62-69.
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Pascale A, Osera C, Moro F, Di Clemente A, Giannotti G, Caffino L, Govoni S, Fumagalli F, Cervo L. Abstinence from cocaine-self-administration activates the nELAV/GAP -43 pathway in the hippocampus: A stress-related effect? Hippocampus. 2016 06; 26(6):700-4.
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Pe?ic V, Milanovic D, Popic J, Smiljanic K, Te?ic V, Kanazir S, Jevtovic-Todorovic V, Ru?dijic S. Neonatal propofol anesthesia modifies activity-dependent processes and induces transient hyperlocomotor response to d-amphetamine during adolescence in rats. Int J Dev Neurosci. 2015 Dec; 47(Pt B):266-77.
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Caprara GA, Perni S, Morabito C, Mariggi? MA, Guarnieri S. Specific association of growth-associated protein 43 with calcium release units in skeletal muscles of lower vertebrates. Eur J Histochem. 2014 Dec 05; 58(4):2453.
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Aungst S, England PM, Thompson SM. Critical role of trkB receptors in reactive axonal sprouting and hyperexcitability after axonal injury. J Neurophysiol. 2013 Feb; 109(3):813-24.
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Law AJ, Pei Q, Walker M, Gordon-Andrews H, Weickert CS, Feldon J, Pryce CR, Harrison PJ. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology. 2009 May; 34(6):1381-94.
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Dinocourt C, Gallagher SE, Thompson SM. Injury-induced axonal sprouting in the hippocampus is initiated by activation of trkB receptors. Eur J Neurosci. 2006 Oct; 24(7):1857-66.
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Young EA, Owen EH, Meiri KF, Wehner JM. Alterations in hippocampal GAP-43 phosphorylation and protein level following contextual fear conditioning. Brain Res. 2000 Mar 31; 860(1-2):95-103.
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Clayton GH, Mahalik TJ, Finger TE. Expression of GAP43 mRNA in normally developing and transplanted neurons from the rat ventral mesencephalon. J Comp Neurol. 1994 Sep 15; 347(3):470-80.
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