 Lyases
"Lyases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyze the cleavage of C-C, C-O, and C-N, and other bonds by other means than by hydrolysis or oxidation. (Enzyme Nomenclature, 1992) EC 4.
| Descriptor ID |
D008190
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| MeSH Number(s) |
D08.811.520
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lyases".
Below are MeSH descriptors whose meaning is more specific than "Lyases".
This graph shows the total number of publications written about "Lyases" by people in this website by year, and whether "Lyases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lyases" by people in Profiles.
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Kuatsjah E, Zahn M, Chen X, Kato R, Hinchen DJ, Konev MO, Katahira R, Orr C, Wagner A, Zou Y, Haugen SJ, Ramirez KJ, Michener JK, Pickford AR, Kamimura N, Masai E, Houk KN, McGeehan JE, Beckham GT. Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc Natl Acad Sci U S A. 2023 01 24; 120(4):e2212246120.
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Brunt VE, Greenberg NT, Sapinsley ZJ, Casso AG, Richey JJ, VanDongen NS, Gioscia-Ryan RA, Ziemba BP, Neilson AP, Davy KP, Seals DR. Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice. J Appl Physiol (1985). 2022 10 01; 133(4):798-813.
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Prates ET, Crowley MF, Skaf MS, Beckham GT. Catalytic Mechanism of Aryl-Ether Bond Cleavage in Lignin by LigF and LigG. J Phys Chem B. 2019 12 05; 123(48):10142-10151.
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Wang B, Eckert C, Maness PC, Yu J. A Genetic Toolbox for Modulating the Expression of Heterologous Genes in the Cyanobacterium Synechocystis sp. PCC 6803. ACS Synth Biol. 2018 01 19; 7(1):276-286.
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Dickhout JG, Carlisle RE, Jerome DE, Mohammed-Ali Z, Jiang H, Yang G, Mani S, Garg SK, Banerjee R, Kaufman RJ, Maclean KN, Wang R, Austin RC. Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012 Mar 02; 287(10):7603-14.
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Pong WW, Stouracova R, Frank N, Kraus JP, Eldred WD. Comparative localization of cystathionine beta-synthase and cystathionine gamma-lyase in retina: differences between amphibians and mammals. J Comp Neurol. 2007 Nov 10; 505(2):158-65.
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Stabler SP, Steegborn C, Wahl MC, Oliveriusova J, Kraus JP, Allen RH, Wagner C, Mudd SH. Elevated plasma total homocysteine in severe methionine adenosyltransferase I/III deficiency. Metabolism. 2002 Aug; 51(8):981-8.
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Copley SD. Microbial dehalogenases: enzymes recruited to convert xenobiotic substrates. Curr Opin Chem Biol. 1998 Oct; 2(5):613-7.
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Ogonowski AA, May SW, Moore AB, Barrett LT, O'Bryant CL, Pollock SH. Antiinflammatory and analgesic activity of an inhibitor of neuropeptide amidation. J Pharmacol Exp Ther. 1997 Feb; 280(2):846-53.
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Sheehy RE, Honma M, Yamada M, Sasaki T, Martineau B, Hiatt WR. Isolation, sequence, and expression in Escherichia coli of the Pseudomonas sp. strain ACP gene encoding 1-aminocyclopropane-1-carboxylate deaminase. J Bacteriol. 1991 Sep; 173(17):5260-5.
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