 Persistent Fetal Circulation Syndrome
"Persistent Fetal Circulation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).
| Descriptor ID |
D010547
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| MeSH Number(s) |
C08.381.423.694 C16.614.694
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| Concept/Terms |
Persistent Fetal Circulation Syndrome- Persistent Fetal Circulation Syndrome
- Pulmonary Hypertension, Familial Persistent, of the Newborn
- ACD-MPV
- ACD MPV
- ACDMPV
- Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins
- Persistent Fetal Circulation
- Circulation, Persistent Fetal
- Familial Persistent Pulmonary Hypertension of the Newborn
- Fetal Circulation, Persistent
- Hypertension, Pulmonary, of Newborn, Persistent
- Misalignment of the Pulmonary Vessels
- Persistent Pulmonary Hypertension of Newborn
- Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins And Other Congenital Anomalies
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Below are MeSH descriptors whose meaning is more general than "Persistent Fetal Circulation Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Persistent Fetal Circulation Syndrome".
This graph shows the total number of publications written about "Persistent Fetal Circulation Syndrome" by people in this website by year, and whether "Persistent Fetal Circulation Syndrome" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 5 | 0 | 5 | | 1995 | 6 | 3 | 9 | | 1996 | 2 | 1 | 3 | | 1997 | 3 | 1 | 4 | | 1998 | 3 | 1 | 4 | | 1999 | 3 | 0 | 3 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 5 | 2 | 7 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2019 | 2 | 0 | 2 | | 2021 | 3 | 0 | 3 | | 2022 | 2 | 0 | 2 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Persistent Fetal Circulation Syndrome" by people in Profiles.
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Galambos C, Logan JW, Stankiewicz P, Szafranski P, Zalles C, Gonzales J, Nath S, Patel S, Abman SH. Histologic features and decreased lung FOXF1 gene expression in severe bronchopulmonary dysplasia without a genetic diagnosis of alveolar capillary dysplasia. Pediatr Pulmonol. 2023 10; 58(10):2746-2749.
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Yildiz B?l?kbasi E, Karolak JA, Szafranski P, Gambin T, Willard N, Abman SH, Galambos C, Kinsella JP, Stankiewicz P. High-level gonosomal mosaicism for a pathogenic non-coding CNV deletion of the lung-specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV. Mol Genet Genomic Med. 2022 Nov; 10(11):e2062.
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Cookson MW, Abman SH, Kinsella JP, Mandell EW. Pulmonary vasodilator strategies in neonates with acute hypoxemic respiratory failure and pulmonary hypertension. Semin Fetal Neonatal Med. 2022 08; 27(4):101367.
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Sun F, Wang G, Pradhan A, Xu K, Gomez-Arroyo J, Zhang Y, Kalin GT, Deng Z, Vagnozzi RJ, He H, Dunn AW, Wang Y, York AJ, Hegde RS, Woods JC, Kalin TV, Molkentin JD, Kalinichenko VV. Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia. Circulation. 2021 08 17; 144(7):539-555.
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Abman SH. Pulmonary Hypertension: The Hidden Danger for Newborns. Neonatology. 2021; 118(2):211-217.
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Mandell E, Kinsella JP, Abman SH. Persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 2021 03; 56(3):661-669.
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Lakshminrusimha S, Kinsella JP, Krishnan US, Van Meurs K, Edwards EM, Bhatt DR, Chandrasekharan P, Oei JL, Manja V, Ramanathan R, Abman SH. Just Say No to iNO in Preterms-Really? J Pediatr. 2020 03; 218:243-252.
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Norvik C, West?? CK, Peruzzi N, Lovric G, van der Have O, Mokso R, Jeremiasen I, Brunnstr?m H, Galambos C, Bech M, Tran-Lundmark K. Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L65-L75.
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Hooper CW, Delaney C, Streeter T, Yarboro MT, Poole S, Brown N, Slaughter JC, Cotton RB, Reese J, Shelton EL. Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero. Am J Physiol Heart Circ Physiol. 2016 09 01; 311(3):H572-81.
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Gien J, Kinsella JP. Management of pulmonary hypertension in infants with congenital diaphragmatic hernia. J Perinatol. 2016 06; 36 Suppl 2:S28-31.
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