Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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James Pearson

TitleAssociate Professor
InstitutionUniversity of Colorado Colorado Springs
DepartmentBeth-El Human Physio/Nutrition
Phone719/255-3806
    Other Positions
    TitleAssoc Chair
    InstitutionUniversity of Colorado Colorado Springs
    DepartmentBeth-El Human Physio/Nutrition


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tracy P, Hill J, Liester J, Sullivan K, Pearson J. Skin heating during simulated hemorrhage lowers arterial blood pressure but not tolerance following exercise in a cold environment. J Appl Physiol (1985). 2024 Nov 01; 137(5):1313-1323. PMID: 39298617.
      View in: PubMed
    2. Tourula E, Lenzini M, Rhodes A, Hetz SE, Pearson J. Facial fanning reduces heart rate but not tolerance to a simulated hemorrhagic challenge following exercise heat stress in young healthy humans. Am J Physiol Regul Integr Comp Physiol. 2024 Mar 01; 326(3):R210-R219. PMID: 38105763.
      View in: PubMed
    3. Pearson JT, Phillips JK, Head GA. Editorial: Insights in integrative physiology: 2022. Front Physiol. 2023; 14:1220684. PMID: 37304816.
      View in: PubMed
    4. Pearson JT, Phillips JK, Head GA. Editorial: Insights in integrative physiology: 2021. Front Physiol. 2023; 14:1186581. PMID: 37064895.
      View in: PubMed
    5. Szulcek R, Johnson CN, Pearson JT, Sequeira V. Editorial: Bridging Techniques: Basic Science of Molecules, Cellular Systems, and Whole-Organ Physiology. Front Physiol. 2022; 13:879396. PMID: 35399270.
      View in: PubMed
    6. Waddingham MT, Tsuchimochi H, Sonobe T, Asano R, Jin H, Ow CPC, Schwenke DO, Katare R, Aoyama K, Umetani K, Hoshino M, Uesugi K, Shirai M, Ogo T, Pearson JT. Using Synchrotron Radiation Imaging Techniques to Elucidate the Actions of Hexarelin in the Heart of Small Animal Models. Front Physiol. 2021; 12:766818. PMID: 35126171.
      View in: PubMed
    7. Inocencio IM, Tran NT, Nakamura S, Khor SJ, Wiersma M, Stoecker K, Polglase GR, Pearson JT, Wong FY. Increased peak end-expiratory pressure in ventilated preterm lambs changes cerebral microvascular perfusion: direct synchrotron microangiography assessment. J Appl Physiol (1985). 2020 11 01; 129(5):1075-1084. PMID: 32909920.
      View in: PubMed
    8. Kawada T, Sonobe T, Nishikawa T, Hayama Y, Li M, Zheng C, Uemura K, Akiyama T, Pearson JT, Sugimachi M. Contribution of afferent pathway to vagal nerve stimulation-induced myocardial interstitial acetylcholine release in rats. Am J Physiol Regul Integr Comp Physiol. 2020 11 01; 319(5):R517-R525. PMID: 32903042.
      View in: PubMed
    9. Trotter CE, Tourula E, Pizzey FK, Batterson PM, Jacobs RA, Pearson J. High-intensity interval exercise reduces tolerance to a simulated haemorrhagic challenge in heat-stressed individuals. Exp Physiol. 2021 01; 106(1):212-221. PMID: 32003866.
      View in: PubMed
    10. Pizzey FK, Tourula E, Pearson J. Tolerance to Central Hypovolemia Is Greater Following Caffeinated Coffee Consumption in Habituated Users. Front Physiol. 2020; 11:50. PMID: 32116762.
      View in: PubMed
    11. Sonobe T, Akiyama T, Du CK, Pearson JT. Serotonin uptake via plasma membrane monoamine transporter during myocardial ischemia-reperfusion in the rat heart in vivo. Physiol Rep. 2019 11; 7(22):e14297. PMID: 31782271.
      View in: PubMed
    12. Waddingham MT, Sonobe T, Tsuchimochi H, Edgley AJ, Sukumaran V, Chen YC, Hansra SS, Schwenke DO, Umetani K, Aoyama K, Yagi N, Kelly DJ, Gaderi S, Herwig M, Kolijn D, M?gge A, Paulus WJ, Ogo T, Shirai M, Hamdani N, Pearson JT. Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model. J Mol Cell Cardiol. 2019 12; 137:119-131. PMID: 31669609.
      View in: PubMed
    13. Kawada T, Sonobe T, Hayama Y, Nishikawa T, Miyamoto T, Akiyama T, Pearson JT, Sugimachi M. Accentuated antagonism of vagal heart rate control and less potent prejunctional inhibition of vagal acetylcholine release during sympathetic nerve stimulation in the rat. Auton Neurosci. 2019 05; 218:25-30. PMID: 30890345.
      View in: PubMed
    14. Trotter CE, Pizzey FK, Batterson PM, Jacobs RA, Pearson J. Small reductions in skin temperature after onset of a simulated hemorrhagic challenge improve tolerance in exercise heat-stressed individuals. Am J Physiol Regul Integr Comp Physiol. 2018 09 01; 315(3):R539-R546. PMID: 30088981.
      View in: PubMed
    15. Katare R, Pearson JT, Lew JK, Wei M, Tsuchimouchi H, Du CK, Zhan DY, Umetani K, Shirai M, Schwenke DO. Progressive Decrease in Coronary Vascular Function Associated With Type 2 Diabetic Heart Disease. Front Physiol. 2018; 9:696. PMID: 29928236.
      View in: PubMed
    16. Sukumaran V, Tsuchimochi H, Fujii Y, Hosoda H, Kangawa K, Akiyama T, Shirai M, Tatsumi E, Pearson JT. Ghrelin Pre-treatment Attenuates Local Oxidative Stress and End Organ Damage During Cardiopulmonary Bypass in Anesthetized Rats. Front Physiol. 2018; 9:196. PMID: 29593559.
      View in: PubMed
    17. Chung S, Nelson MD, Hamaoka T, Jacobs RA, Pearson J, Subudhi AW, Jenkins NT, Bartlett MF, Fitzgerald LF, Miehm JD, Kent JA, Lucero AA, Rowlands DS, Stoner L, McCully KK, Call J, Rodriguez-Miguelez P, Harris RA, Porcelli S, Rasica L, Marzorati M, Quaresima V, Ryan TE, Vernillo G, Millet GP, Malatesta D, Millet GY, Zuo L, Chuang CC. Commentaries on Viewpoint: Principles, insights, and potential pitfalls of the noninvasive determination of muscle oxidative capacity by near-infrared spectroscopy. J Appl Physiol (1985). 2018 01 01; 124(1):249-255. PMID: 29364790.
      View in: PubMed
    18. Borner A, Murray K, Trotter C, Pearson J. Baseline aortic pulse wave velocity is associated with central and peripheral pressor responses during the cold pressor test in healthy subjects. Physiol Rep. 2017 Jul; 5(14). PMID: 28733312.
      View in: PubMed
    19. Garrett ZK, Pearson J, Subudhi AW. Postural effects on cerebral blood flow and autoregulation. Physiol Rep. 2017 Feb; 5(4). PMID: 28242827.
      View in: PubMed
    20. Pearson J, Lucas RA, Schlader ZJ, Gagnon D, Crandall CG. Elevated skin and core temperatures both contribute to reductions in tolerance to a simulated haemorrhagic challenge. Exp Physiol. 2017 02 01; 102(2):255-264. PMID: 27981648.
      View in: PubMed
    21. Pearson J, Ganio MS, Schlader ZJ, Lucas RA, Gagnon D, Rivas E, Davis SL, Kowalske KJ, Crandall CG. Post Junctional Sudomotor and Cutaneous Vascular Responses in Noninjured Skin Following Heat Acclimation in Burn Survivors. J Burn Care Res. 2017 Jan/Feb; 38(1):e284-e292. PMID: 27359190.
      View in: PubMed
    22. Ngo JP, Ow CP, Gardiner BS, Kar S, Pearson JT, Smith DW, Evans RG. Diffusive shunting of gases and other molecules in the renal vasculature: physiological and evolutionary significance. Am J Physiol Regul Integr Comp Physiol. 2016 11 01; 311(5):R797-R810. PMID: 27488891.
      View in: PubMed
    23. Chen YC, Inagaki T, Fujii Y, Schwenke DO, Tsuchimochi H, Edgley AJ, Umetani K, Zhang Y, Kelly DJ, Yoshimoto M, Nagai H, Evans RG, Kuwahira I, Shirai M, Pearson JT. Chronic intermittent hypoxia accelerates coronary microcirculatory dysfunction in insulin-resistant Goto-Kakizaki rats. Am J Physiol Regul Integr Comp Physiol. 2016 08 01; 311(2):R426-39. PMID: 27252472.
      View in: PubMed
    24. van Mil AC, Pearson J, Drane AL, Cockcroft JR, McDonnell BJ, St?hr EJ. Interaction between left ventricular twist mechanics and arterial haemodynamics during localised, non-metabolic hyperaemia with and without blood flow restriction. Exp Physiol. 2016 Apr; 101(4):509-20. PMID: 26800643.
      View in: PubMed
    25. Pearson JT. Cardiac responses to hypoxia and reoxygenation in Drosophila. New insights into evolutionarily conserved gene responses. Focus on "Cardiac responses to hypoxia and reoxygenation in Drosophila". Am J Physiol Regul Integr Comp Physiol. 2015 Dec 01; 309(11):R1344-6. PMID: 26447213.
      View in: PubMed
    26. Ganio MS, Schlader ZJ, Pearson J, Lucas RA, Gagnon D, Rivas E, Kowalske KJ, Crandall CG. Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans. Med Sci Sports Exerc. 2015 Oct; 47(10):2224-32. PMID: 26378947.
      View in: PubMed
    27. Lucas RA, Pearson J, Schlader ZJ, Crandall CG. Cardiopulmonary and arterial baroreceptor unloading during passive hyperthermia does not contribute to hyperthermia-induced hyperventilation. Exp Physiol. 2015 Nov; 100(11):1309-18. PMID: 26299270.
      View in: PubMed
    28. Ganio MS, Pearson J, Schlader ZJ, Brothers RM, Lucas RA, Rivas E, Kowalske KJ, Crandall CG. Aerobic Fitness Is Disproportionately Low in Adult Burn Survivors Years After Injury. J Burn Care Res. 2015 Jul-Aug; 36(4):513-9. PMID: 24043241.
      View in: PubMed
    29. Schlader ZJ, Ganio MS, Pearson J, Lucas RA, Gagnon D, Rivas E, Kowalske KJ, Crandall CG. Heat acclimation improves heat exercise tolerance and heat dissipation in individuals with extensive skin grafts. J Appl Physiol (1985). 2015 Jul 01; 119(1):69-76. PMID: 25930025.
      View in: PubMed
    30. Lucas RA, Sarma S, Schlader ZJ, Pearson J, Crandall CG. Age-related changes to cardiac systolic and diastolic function during whole-body passive hyperthermia. Exp Physiol. 2015 Apr 01; 100(4):422-34. PMID: 25641368.
      View in: PubMed
    31. Schlader ZJ, Gagnon D, Lucas RA, Pearson J, Crandall CG. Baroreceptor unloading does not limit forearm sweat rate during severe passive heat stress. J Appl Physiol (1985). 2015 Feb 15; 118(4):449-54. PMID: 25525210.
      View in: PubMed
    32. Lang JA, Pearson JT, te Pas AB, Wallace MJ, Siew ML, Kitchen MJ, Fouras A, Lewis RA, Wheeler KI, Polglase GR, Shirai M, Sonobe T, Hooper SB. Ventilation/perfusion mismatch during lung aeration at birth. J Appl Physiol (1985). 2014 Sep 01; 117(5):535-43. PMID: 24994883.
      View in: PubMed
    33. Lucas RA, Pearson J, Schlader ZJ, Crandall CG. Hypercapnia-induced increases in cerebral blood flow do not improve lower body negative pressure tolerance during hyperthermia. Am J Physiol Regul Integr Comp Physiol. 2013 Sep 15; 305(6):R604-9. PMID: 23864641.
      View in: PubMed
    34. Schlader ZJ, Lucas RA, Pearson J, Crandall CG. Hyperthermia does not alter the increase in cerebral perfusion during cognitive activation. Exp Physiol. 2013 Nov; 98(11):1597-607. PMID: 23851918.
      View in: PubMed
    35. Lucas RA, Ganio MS, Pearson J, Crandall CG. Brain blood flow and cardiovascular responses to hot flashes in postmenopausal women. Menopause. 2013 Mar; 20(3):299-304. PMID: 23435027.
      View in: PubMed
    36. Schlader ZJ, Lucas RA, Pearson J, Crandall CG. One of these things is not like the other: the heterogeneity of the cerebral circulation. J Physiol. 2013 Jan 15; 591(2):395-7. PMID: 23322292.
      View in: PubMed
    37. Pearson J, Kalsi KK, St?hr EJ, Low DA, Barker H, Ali L, Gonz?lez-Alonso J. Haemodynamic responses to dehydration in the resting and exercising human leg. Eur J Appl Physiol. 2013 Jun; 113(6):1499-509. PMID: 23288036.
      View in: PubMed
    38. Lucas RA, Ganio MS, Pearson J, Crandall CG. Sweat loss during heat stress contributes to subsequent reductions in lower-body negative pressure tolerance. Exp Physiol. 2013 Feb; 98(2):473-80. PMID: 22872657.
      View in: PubMed
    39. Pearson J, Ganio MS, Seifert T, Overgaard M, Secher NH, Crandall CG. Pulmonary artery and intestinal temperatures during heat stress and cooling. Med Sci Sports Exerc. 2012 May; 44(5):857-62. PMID: 22015711.
      View in: PubMed
    40. Gagnon D, Ganio MS, Lucas RA, Pearson J, Crandall CG, Kenny GP. Modified iodine-paper technique for the standardized determination of sweat gland activation. J Appl Physiol (1985). 2012 Apr; 112(8):1419-25. PMID: 22323650.
      View in: PubMed
    41. Laitano O, Kalsi KK, Pearson J, Lotlikar M, Reischak-Oliveira A, Gonz?lez-Alonso J. Effects of graded exercise-induced dehydration and rehydration on circulatory markers of oxidative stress across the resting and exercising human leg. Eur J Appl Physiol. 2012 May; 112(5):1937-44. PMID: 21932069.
      View in: PubMed
    42. St?hr EJ, Gonz?lez-Alonso J, Pearson J, Low DA, Ali L, Barker H, Shave R. Dehydration reduces left ventricular filling at rest and during exercise independent of twist mechanics. J Appl Physiol (1985). 2011 Sep; 111(3):891-7. PMID: 21700893.
      View in: PubMed
    43. Sonobe T, Schwenke DO, Pearson JT, Yoshimoto M, Fujii Y, Umetani K, Shirai M. Imaging of the closed-chest mouse pulmonary circulation using synchrotron radiation microangiography. J Appl Physiol (1985). 2011 Jul; 111(1):75-80. PMID: 21527665.
      View in: PubMed
    44. Schwenke DO, Pearson JT, Sonobe T, Ishibashi-Ueda H, Shimouchi A, Kangawa K, Umetani K, Shirai M. Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension. J Appl Physiol (1985). 2011 Apr; 110(4):901-8. PMID: 21212241.
      View in: PubMed
    45. Pearson J, Low DA, St?hr E, Kalsi K, Ali L, Barker H, Gonz?lez-Alonso J. Hemodynamic responses to heat stress in the resting and exercising human leg: insight into the effect of temperature on skeletal muscle blood flow. Am J Physiol Regul Integr Comp Physiol. 2011 Mar; 300(3):R663-73. PMID: 21178127.
      View in: PubMed
    46. St?hr EJ, Gonz?lez-Alonso J, Pearson J, Low DA, Ali L, Barker H, Shave R. Effects of graded heat stress on global left ventricular function and twist mechanics at rest and during exercise in healthy humans. Exp Physiol. 2011 Feb; 96(2):114-24. PMID: 20952488.
      View in: PubMed
    47. Dufour SP, Patel RP, Brandon A, Teng X, Pearson J, Barker H, Ali L, Yuen AH, Smolenski RT, Gonz?lez-Alonso J. Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP. Am J Physiol Heart Circ Physiol. 2010 Dec; 299(6):H1936-46. PMID: 20852046.
      View in: PubMed
    48. Foti RS, Dickmann LJ, Davis JA, Greene RJ, Hill JJ, Howard ML, Pearson JT, Rock DA, Tay JC, Wahlstrom JL, Slatter JG. Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements. Xenobiotica. 2008 Mar; 38(3):264-80. PMID: 18274956.
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    49. Schwenke DO, Pearson JT, Kangawa K, Umetani K, Shirai M. Changes in macrovessel pulmonary blood flow distribution following chronic hypoxia: assessed using synchrotron radiation microangiography. J Appl Physiol (1985). 2008 Jan; 104(1):88-96. PMID: 17962580.
      View in: PubMed
    50. Schwenke DO, Pearson JT, Umetani K, Kangawa K, Shirai M. Imaging of the pulmonary circulation in the closed-chest rat using synchrotron radiation microangiography. J Appl Physiol (1985). 2007 Feb; 102(2):787-93. PMID: 17038493.
      View in: PubMed
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