Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

David Wyles

Concepts (232)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Antiviral Agents
57
2022
635
11.790
Why?
Hepatitis C, Chronic
30
2022
150
8.640
Why?
Hepacivirus
46
2024
228
7.940
Why?
Hepatitis C
26
2024
218
7.550
Why?
Benzimidazoles
16
2020
137
4.500
Why?
Drug Resistance, Viral
17
2018
99
3.380
Why?
HIV Infections
28
2022
2440
3.350
Why?
Coinfection
15
2020
119
3.220
Why?
Ribavirin
15
2020
89
2.430
Why?
Sulfonamides
13
2020
442
2.410
Why?
Sofosbuvir
16
2022
53
2.370
Why?
Quinoxalines
7
2019
60
2.360
Why?
Liver Cirrhosis
8
2020
226
2.350
Why?
Fluorenes
7
2020
38
2.320
Why?
Viral Nonstructural Proteins
9
2018
54
2.030
Why?
Drug Therapy, Combination
26
2020
944
1.930
Why?
Uridine Monophosphate
5
2016
15
1.750
Why?
Carbamates
9
2020
33
1.540
Why?
Anti-Retroviral Agents
5
2019
207
1.510
Why?
Protease Inhibitors
10
2020
96
1.430
Why?
Hepatitis B, Chronic
3
2019
18
1.400
Why?
Proline
11
2020
72
1.330
Why?
Pyrrolidines
9
2019
55
1.260
Why?
Congresses as Topic
3
2021
194
1.230
Why?
Hepatitis, Viral, Human
3
2021
25
1.190
Why?
Genotype
19
2022
1733
1.050
Why?
Cyclopropanes
11
2020
78
1.020
Why?
Drug Users
2
2024
41
1.000
Why?
Sustained Virologic Response
10
2020
33
0.950
Why?
Lactams, Macrocyclic
10
2020
46
0.940
Why?
HIV-1
8
2020
764
0.850
Why?
Heterocyclic Compounds, 4 or More Rings
3
2017
15
0.840
Why?
Virus Replication
7
2012
392
0.800
Why?
Disease Eradication
1
2020
4
0.730
Why?
Humans
73
2024
113531
0.710
Why?
Anti-HIV Agents
6
2020
660
0.710
Why?
Organophosphonates
4
2011
88
0.700
Why?
Homosexuality, Male
2
2021
169
0.700
Why?
Valine
7
2020
72
0.660
Why?
Nucleic Acid Synthesis Inhibitors
2
2015
15
0.580
Why?
Imidazoles
2
2015
203
0.570
Why?
Ritonavir
6
2020
69
0.560
Why?
Treatment Outcome
18
2023
9006
0.550
Why?
Darunavir
1
2017
16
0.550
Why?
Treatment Failure
5
2019
323
0.550
Why?
Aminoisobutyric Acids
5
2019
7
0.540
Why?
Middle Aged
28
2021
26552
0.530
Why?
Uracil
5
2020
28
0.520
Why?
Antiretroviral Therapy, Highly Active
3
2015
254
0.510
Why?
Leucine
5
2019
102
0.510
Why?
Anilides
5
2020
67
0.510
Why?
Male
37
2022
55112
0.500
Why?
Biomedical Research
1
2021
581
0.490
Why?
Education, Medical, Continuing
1
2016
115
0.490
Why?
Adenine
4
2020
217
0.470
Why?
RNA, Viral
7
2015
562
0.470
Why?
Oligopeptides
2
2013
231
0.460
Why?
Viral Load
7
2020
403
0.460
Why?
Pyridazines
1
2014
46
0.450
Why?
Adult
27
2023
30245
0.450
Why?
Female
35
2022
59115
0.450
Why?
2-Naphthylamine
5
2020
7
0.440
Why?
Liver
1
2021
1630
0.430
Why?
Macrocyclic Compounds
3
2019
9
0.430
Why?
Quinolines
1
2014
127
0.420
Why?
Purines
1
2014
158
0.420
Why?
Replicon
3
2009
14
0.410
Why?
Disease Management
1
2016
554
0.400
Why?
Aged
16
2021
18944
0.400
Why?
Scavenger Receptors, Class B
1
2012
8
0.390
Why?
Retreatment
2
2021
67
0.350
Why?
Drug Synergism
3
2008
312
0.350
Why?
Acquired Immunodeficiency Syndrome
2
2020
212
0.310
Why?
Liver Diseases
2
2016
254
0.310
Why?
Dideoxynucleosides
2
2005
19
0.300
Why?
Cytokines
1
2015
1795
0.290
Why?
Interferon-alpha
4
2013
184
0.290
Why?
Global Health
2
2020
287
0.280
Why?
Amino Acid Substitution
2
2018
260
0.270
Why?
Cytosine
2
2009
43
0.270
Why?
Mass Screening
3
2023
978
0.260
Why?
Hepatitis B virus
2
2019
25
0.240
Why?
HIV
2
2019
205
0.240
Why?
Herpes Simplex
1
2005
87
0.230
Why?
Hepatitis
1
2004
46
0.230
Why?
Alanine
2
2021
104
0.230
Why?
Prevalence
3
2019
2244
0.220
Why?
Young Adult
10
2019
10400
0.220
Why?
Interferons
2
2015
149
0.210
Why?
Hospitals
2
2024
582
0.200
Why?
Mutation, Missense
3
2014
293
0.200
Why?
Interferon beta-1a
1
2021
12
0.190
Why?
Adenosine Monophosphate
1
2021
49
0.190
Why?
Tenofovir
2
2020
203
0.190
Why?
Hepatitis A
1
2021
26
0.180
Why?
Disease Progression
2
2019
2364
0.180
Why?
Hepatitis B
1
2021
51
0.180
Why?
World Health Organization
1
2020
101
0.170
Why?
Data Interpretation, Statistical
2
2018
315
0.170
Why?
Polyethylene Glycols
2
2015
557
0.160
Why?
Ribosomes
2
2010
146
0.160
Why?
Esters
2
2009
62
0.160
Why?
CD4 Lymphocyte Count
2
2017
253
0.150
Why?
Immunologic Factors
1
2020
211
0.150
Why?
Nucleic Acid Conformation
4
2014
666
0.150
Why?
DNA, Viral
1
2019
345
0.140
Why?
Alanine Transaminase
1
2018
140
0.140
Why?
Mutation
2
2018
3313
0.140
Why?
Adolescent
5
2022
17724
0.140
Why?
Genes, Viral
1
2016
88
0.140
Why?
DNA Mutational Analysis
1
2018
372
0.130
Why?
High-Throughput Nucleotide Sequencing
2
2016
435
0.130
Why?
United States
8
2022
12137
0.130
Why?
Patient Compliance
1
2020
523
0.130
Why?
Molecular Structure
2
2008
429
0.130
Why?
Survival Analysis
1
2019
1203
0.130
Why?
Dose-Response Relationship, Drug
2
2017
1822
0.130
Why?
Opiate Substitution Treatment
1
2016
99
0.120
Why?
Hospitalization
1
2024
1765
0.120
Why?
Regulatory Sequences, Ribonucleic Acid
1
2014
17
0.120
Why?
AIDS-Related Opportunistic Infections
1
2015
114
0.120
Why?
Chemokines
1
2015
214
0.110
Why?
Chemokine CXCL10
1
2014
32
0.110
Why?
Viral Proteins
2
2014
280
0.110
Why?
Drug Interactions
1
2015
332
0.110
Why?
Fibrosis
1
2016
452
0.110
Why?
Prognosis
2
2019
3318
0.110
Why?
Phenylenediamines
1
2013
5
0.110
Why?
Microbial Sensitivity Tests
2
2012
298
0.110
Why?
Drug Combinations
3
2019
285
0.110
Why?
Mental Disorders
1
2020
884
0.100
Why?
Drug Discovery
1
2013
122
0.100
Why?
Case-Control Studies
2
2017
2993
0.100
Why?
Telemedicine
1
2020
666
0.100
Why?
Administration, Oral
1
2014
719
0.100
Why?
Models, Molecular
3
2012
1359
0.090
Why?
Drug-Related Side Effects and Adverse Reactions
1
2013
239
0.090
Why?
Prodrugs
1
2011
42
0.090
Why?
Prospective Studies
4
2023
6189
0.090
Why?
Cell Line, Tumor
2
2008
2690
0.090
Why?
Nucleosides
1
2010
25
0.090
Why?
Riboswitch
1
2012
63
0.090
Why?
Biomarkers
1
2020
3389
0.090
Why?
Japan
2
2021
85
0.090
Why?
Risk Assessment
1
2019
2953
0.090
Why?
Drug Administration Schedule
3
2017
712
0.080
Why?
Body Mass Index
1
2017
1952
0.080
Why?
Drug Design
1
2010
146
0.080
Why?
Cell Line
2
2012
2581
0.080
Why?
Piperidines
1
2010
159
0.080
Why?
Practice Guidelines as Topic
1
2016
1378
0.080
Why?
Immunity, Innate
1
2014
716
0.080
Why?
Phenylthiourea
1
2008
5
0.080
Why?
Plasmids
1
2009
334
0.070
Why?
Structure-Activity Relationship
1
2009
497
0.070
Why?
Cohort Studies
4
2023
4880
0.070
Why?
Inhibitory Concentration 50
1
2006
74
0.070
Why?
Luciferases
1
2006
139
0.070
Why?
Genes, Reporter
1
2006
248
0.060
Why?
Pregnancy
1
2017
5490
0.060
Why?
Time Factors
1
2015
6032
0.060
Why?
Saquinavir
1
2004
1
0.060
Why?
Carcinoma, Hepatocellular
1
2006
210
0.060
Why?
Simplexvirus
1
2005
80
0.060
Why?
Indinavir
1
2004
6
0.060
Why?
Nelfinavir
1
2004
8
0.060
Why?
Drug Labeling
1
2005
42
0.060
Why?
Nevirapine
1
2004
16
0.060
Why?
Oxazines
1
2004
25
0.060
Why?
Benzoxazines
1
2004
27
0.060
Why?
Lopinavir
1
2004
29
0.060
Why?
Alkynes
1
2004
52
0.060
Why?
Transfection
1
2006
842
0.060
Why?
Zidovudine
1
2004
77
0.060
Why?
Liver Function Tests
1
2004
104
0.060
Why?
Reverse Transcriptase Inhibitors
1
2004
80
0.060
Why?
Bone Marrow Transplantation
1
2005
234
0.060
Why?
Pyrimidinones
1
2004
88
0.060
Why?
Recombinant Fusion Proteins
1
2006
599
0.060
Why?
Double-Blind Method
2
2021
1643
0.060
Why?
Liver Neoplasms
1
2006
504
0.050
Why?
Retrospective Studies
5
2019
12504
0.050
Why?
Polyphosphates
1
2022
33
0.050
Why?
Emergency Service, Hospital
2
2023
1815
0.050
Why?
Singapore
1
2021
14
0.050
Why?
Republic of Korea
1
2021
27
0.050
Why?
Dried Blood Spot Testing
1
2022
71
0.050
Why?
Protein Biosynthesis
2
2014
375
0.050
Why?
Mexico
1
2021
160
0.050
Why?
Raltegravir Potassium
1
2019
16
0.040
Why?
Clinical Trials, Phase II as Topic
1
2019
59
0.040
Why?
Clinical Trials, Phase III as Topic
1
2019
82
0.040
Why?
Drug Resistance, Multiple, Viral
1
2017
11
0.040
Why?
Oxygen
1
2021
827
0.030
Why?
Kinetics
1
2020
1528
0.030
Why?
Incidence
2
2013
2310
0.030
Why?
Medicaid
1
2020
404
0.030
Why?
RNA
1
2022
801
0.030
Why?
Program Evaluation
1
2020
821
0.030
Why?
Patient Reported Outcome Measures
1
2017
251
0.030
Why?
Cell-Free System
1
2014
45
0.030
Why?
Pandemics
1
2023
1308
0.030
Why?
Hepatitis C Antibodies
1
2014
9
0.030
Why?
Aged, 80 and over
2
2019
6296
0.030
Why?
Spain
1
2014
32
0.030
Why?
Risk Factors
2
2020
8606
0.030
Why?
Patient Acceptance of Health Care
1
2020
679
0.030
Why?
Enzyme-Linked Immunosorbent Assay
1
2016
783
0.030
Why?
Polymorphism, Genetic
1
2017
603
0.030
Why?
Patient Care
1
2014
99
0.030
Why?
Withholding Treatment
1
2013
66
0.030
Why?
Early Diagnosis
1
2014
218
0.030
Why?
Plasma
1
2014
180
0.030
Why?
Fluorescence Resonance Energy Transfer
1
2012
167
0.020
Why?
Pilot Projects
1
2015
1356
0.020
Why?
Virus Internalization
1
2010
40
0.020
Why?
Ligands
1
2012
553
0.020
Why?
Recombinant Proteins
1
2013
1214
0.020
Why?
Referral and Consultation
1
2014
632
0.020
Why?
Magnesium
1
2009
144
0.020
Why?
Lamivudine
1
2009
58
0.020
Why?
Genome, Viral
1
2009
118
0.020
Why?
Logistic Models
1
2013
1832
0.020
Why?
Phenotype
1
2014
2754
0.020
Why?
Severity of Illness Index
1
2013
2530
0.020
Why?
Base Sequence
1
2009
2080
0.020
Why?
Randomized Controlled Trials as Topic
1
2011
1205
0.020
Why?
Mice, Transgenic
1
2009
1925
0.010
Why?
Animals
2
2018
31162
0.010
Why?
Substance-Related Disorders
1
2011
931
0.010
Why?
Signal Transduction
1
2009
4439
0.010
Why?
Mice
1
2009
14679
0.010
Why?
Wyles's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
_
Co-Authors Expand Description
_
Similar People Expand Description
_
Same Department Expand Description
Physical Neighbors Expand Description
_

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)