 Withholding Treatment
"Withholding Treatment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Withholding or withdrawal of a particular treatment or treatments, often (but not necessarily) life-prolonging treatment, from a patient or from a research subject as part of a research protocol. The concept is differentiated from REFUSAL TO TREAT, where the emphasis is on the health professional's or health facility's refusal to treat a patient or group of patients when the patient or the patient's representative requests treatment. Withholding of life-prolonging treatment is usually indexed only with EUTHANASIA, PASSIVE, unless the distinction between withholding and withdrawing treatment, or the issue of withholding palliative rather than curative treatment, is discussed.
| Descriptor ID |
D028761
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| MeSH Number(s) |
E02.760.952 N02.421.585.952
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| Concept/Terms |
Withholding Treatment- Withholding Treatment
- Treatment, Withholding
- Treatments, Withholding
- Withholding Treatments
- Cessation of Treatment
- Treatment Cessation
- Treatment Cessations
Withdrawing Treatment- Withdrawing Treatment
- Treatment, Withdrawing
- Treatments, Withdrawing
- Withdrawing Treatments
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Below are MeSH descriptors whose meaning is more general than "Withholding Treatment".
Below are MeSH descriptors whose meaning is more specific than "Withholding Treatment".
This graph shows the total number of publications written about "Withholding Treatment" by people in this website by year, and whether "Withholding Treatment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 2 | 4 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 2 | 2 | 4 | | 2014 | 4 | 1 | 5 | | 2015 | 2 | 1 | 3 | | 2016 | 3 | 3 | 6 | | 2017 | 2 | 1 | 3 | | 2018 | 0 | 1 | 1 | | 2019 | 3 | 3 | 6 | | 2020 | 3 | 0 | 3 | | 2021 | 2 | 1 | 3 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Withholding Treatment" by people in Profiles.
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Derman BA, Major A, Cooperrider J, Jiang K, Ramsland A, Karrison T, Kubicki T, Jakubowiak AJ. Discontinuation of maintenance therapy in multiple myeloma guided by multimodal measurable residual disease negativity (MRD2STOP). Blood Cancer J. 2024 Oct 07; 14(1):170.
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Pringle CP, Filipp SL, Morrison WE, Fainberg NA, Aczon MD, Avesar M, Burkiewicz KF, Chandnani HK, Hsu SC, Laksana E, Ledbetter DR, McCrory MC, Morrow KR, Noguchi AE, O'Brien CE, Ojha A, Ross PA, Shah S, Shah JK, Siegel LB, Tripathi S, Wetzel RC, Zhou AX, Winter MC. Ventilator Weaning and Terminal Extubation: Withdrawal of Life-Sustaining Therapy in Children. Secondary Analysis of the Death One Hour After Terminal Extubation Study. Crit Care Med. 2024 03 01; 52(3):396-406.
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Partridge AH, Niman SM, Ruggeri M, Peccatori FA, Azim HA, Colleoni M, Saura C, Shimizu C, S?tersdal AB, Kroep JR, Mailliez A, Warner E, Borges VF, Amant F, Gombos A, Kataoka A, Rousset-Jablonski C, Borstnar S, Takei J, Lee JE, Walshe JM, Ru?z-Borrego M, Moore HCF, Saunders C, Bjelic-Radisic V, Susnjar S, Cardoso F, Smith KL, Ferreiro T, Ribi K, Ruddy K, Kammler R, El-Abed S, Viale G, Piccart M, Korde LA, Goldhirsch A, Gelber RD, Pagani O. Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer. N Engl J Med. 2023 May 04; 388(18):1645-1656.
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de Joode K, Tol J, Hamberg P, Cloos M, Kastelijn EA, Borgers JSW, Nuij VJAA, Klaver Y, Herder GJM, Mutsaers PGNJ, Dumoulin DW, Oomen-de Hoop E, van Diemen NGJ, Libourel EJ, Geraedts EJ, Bootsma GP, van der Leest CH, Peerdeman AL, Herbschleb KH, Visser OJ, Bloemendal HJ, van Laarhoven HWM, de Vries EGE, Hendriks LEL, Beerepoot LV, Westgeest HM, van den Berkmortel FWPJ, Haanen JBAG, Dingemans AC, van der Veldt AAM. Life-prolonging treatment restrictions and outcomes in patients with cancer and COVID-19: an update from the Dutch Oncology COVID-19 Consortium. Eur J Cancer. 2022 01; 160:261-272.
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Strijbis EMM, Kerbrat A, Corboy JR. Discontinuation of Disease-Modifying Therapy in Multiple Sclerosis: Should We Stay or Should We Go? JAMA Neurol. 2021 07 01; 78(7):787-788.
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Dagenais GR, Dyal L, Bosch JJ, Leong DP, Aboyans V, Berkowitz SD, Bhatt DL, Connolly SJ, Fox KAA, Muehlhofer E, Probstfield JL, Widimsky P, Winkelmann BR, Yusuf S, Eikelboom JW. Cardiovascular consequences of discontinuing low-dose rivaroxaban in people with chronic coronary or peripheral artery disease. Heart. 2021 07; 107(14):1130-1137.
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Binswanger IA, Glanz JM, Faul M, Shoup JA, Quintana LM, Lyden J, Xu S, Narwaney KJ. The Association between Opioid Discontinuation and Heroin Use: A Nested Case-Control Study. Drug Alcohol Depend. 2020 12 01; 217:108248.
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Chase D, Huang HQ, Monk BJ, Ramondetta LM, Penson RT, Gil K, Landrum LM, Leitao M, Oaknin A, Huh WK, Pulaski HL, Robison K, Guntupalli SR, Richardson D, Salani R, Sill MW, Wenzel LB, Tewari KS. Patient-reported outcomes at discontinuation of anti-angiogenesis therapy in the randomized trial of chemotherapy with bevacizumab for advanced cervical cancer: an NRG Oncology Group study. Int J Gynecol Cancer. 2020 05; 30(5):596-601.
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Murphy RF, Barfield WR, St Hilaire T, Smith JT, Emans JB, Samdani A, Garg S, Sawyer JR, Pahys JM. Prospectively collected surgeon indications for discontinuation of a lengthening program for early-onset scoliosis. Spine Deform. 2020 02; 8(1):129-133.
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Wright N, Voshtina E, George G, Singavi A, Field J. Cryoglobulinemic vasculitis with interruption of ibrutinib therapy for chronic lymphocytic leukemia (CLL). Int J Hematol. 2019 Dec; 110(6):751-755.
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