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																		 Pragmatic Clinical Trials as Topic
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Pragmatic Clinical Trials as Topic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				Works about randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts.
    
			 
				
				
					
						| Descriptor ID | D064792 |  
						| MeSH Number(s) | E05.318.760.250.500.365.500.500 N05.715.360.775.088.500.387.500.750 N06.850.520.450.250.250.365.500.750 |  
						| Concept/Terms | Pragmatic Clinical Trials as TopicPragmatic Clinical Trials as TopicReal World Clinical TrialsNaturalistic Randomized Clinical TrialPragmatic TrialsTrials, PragmaticPragmatic Clinical TrialsClinical Trials, PragmaticTrials, Pragmatic ClinicalPractical Clinical TrialsClinical Trials, PracticalTrials, Practical Clinical
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				Below are MeSH descriptors whose meaning is more general than "Pragmatic Clinical Trials as Topic". 
				Below are MeSH descriptors whose meaning is more specific than "Pragmatic Clinical Trials as Topic". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Pragmatic Clinical Trials as Topic" by people in this website by year, and whether "Pragmatic Clinical Trials as Topic" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 2013 | 2 | 0 | 2 |  | 2014 | 3 | 0 | 3 |  | 2015 | 0 | 2 | 2 |  | 2016 | 1 | 0 | 1 |  | 2017 | 2 | 2 | 4 |  | 2018 | 1 | 1 | 2 |  | 2019 | 0 | 2 | 2 |  | 2020 | 1 | 4 | 5 |  | 2021 | 1 | 4 | 5 |  | 2022 | 2 | 3 | 5 |  | 2023 | 0 | 1 | 1 |  | 2024 | 1 | 5 | 6 |  | 2025 | 0 | 4 | 4 | 
 
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				Below are the most recent publications written about "Pragmatic Clinical Trials as Topic" by people in Profiles. 		
					
								
								Canonico ME, Hsia J, Masoudi FA, Bosworth HB, Greene S, Batch BC, Hamilton N, de Araujo TB, Jackson M, Broussard M, Gooden Z, Guthrie NL, Hansell B, Matteliano-Madu L, Mosesso K, Berman MA, Bonaca MP. Digital Therapeutic Based Randomized Investigation to Improve Glycemic Control in Patients With Type 2 Diabetes and Residual Hyperglycemia on Stable Medical Therapy: Rationale, Design, and Baseline Characteristics of the BRIGHT Trial. J Am Heart Assoc. 2025 Aug 05; 14(15):e038737.
								Donovan LM, Feemster LC, Collins MP, Gleason EE, Josey K, Duan KI, Plumley R, Coggeshall S, Wai TH, Petrova V, Trenaman L, Atwood M, Ballance P, Baldomero AK, Gillen F, Gunter J, Isaac J, Kara H, Kizer KW, Lambert AA, Liao JM, Lindenauer PK, Llamas W, Martinez N, McDowell J, McFarland MS, McGrath A, Melzer AC, Mog AC, Rommes J, Slatore CG, Strychalski ML, Tanner NT, Yarbrough WC, Au DH. Protocol for a pragmatic trial to enhance quality safety, and patient experience in chronic obstructive pulmonary disease (EQuiP-COPD). Contemp Clin Trials. 2025 Aug; 155:107961.
								Singh S, Nguyen JD, Fudman DI, Gerich ME, Shah SA, Hudesman D, McConnell RA, Lukin DJ, Flynn AD, Hwang C, Sprung B, Gaidos JKJ, Mattar MC, Rubin DT, Hashash JG, Metwally M, Ali T, Ma C, Hoentjen F, Narula N, Bessissow T, Rosenfeld G, McCurdy JD, Ananthakrishnan AN, Cross RK, Rodriguez Gaytan JR, Gurrola ES, Patel S, Siegel CA, Melmed GY, Weaver SA, Power S, Zou G, Jairath V, Hou JK. Treat-to-target of endoscopic remission in patients with inflammatory bowel disease in symptomatic remission on advanced therapies (QUOTIENT): rationale, design and protocol for an open-label, multicentre, pragmatic, randomised controlled trial. BMJ Open Gastroenterol. 2025 Mar 31; 12(1).
								Disher N, Dieckmann NF, Case JR, Rubim F, Eden KB, Golden SE, Matlock DD, Coleman C, Lyons KS, Saha S, Slatore CG, Vranas KC, Sullivan DR. Improving lung cancer decision-making using a conversation tool (iDECIDE): a stepped wedge pragmatic clinical trial. Future Oncol. 2025 Apr; 21(9):1045-1056.
								Toerper MF, Haukoos J, Hopkins E, Rowan SE, Lyons MS, Galbraith JW, Hsieh YH, White DA, Levin S, Hinson J, Rothman RE. Use of Epic? to facilitate high-quality randomization of emergency department-based pragmatic clinical trials. Clin Trials. 2025 Apr; 22(2):142-151.
								Zittleman L, Westfall JM, Sofie B, Lutgen C, Fernald D, Hall TL, Hochheimer CJ, Murphy M, Felzien M, Dickinson LM, Manning BK, LeMaster J, Nease DE. The Odyssey of HOMER: Comparative Effectiveness Research on Medication for Opioid Use Disorder During the COVID-19 Pandemic. Ann Fam Med. 2024 Sep-Oct; 22(5):444-450.
								Bekelman DB, Giannitrapani K, Linn KA, Langner P, Sudore RL, Rabin B, Lorenz KA, Foglia M, Glickman A, Pawlikowski S, Sloan M, Gamboa RC, McCaa MD, Hines A, Walling AM. Increasing goals of care conversations in primary care: Study protocol for a cluster randomized, pragmatic, sequential multiple assignment randomized trial. Contemp Clin Trials. 2024 Oct; 145:107643.
								Fortney JC, Kaysen DL, Engel CC, Cerimele JM, Nolan JP, Chase E, Blanchard BE, Hauge S, Bechtel J, Moore DL, Taylor A, Acierno R, Nagel N, Sripada RK, Painter JT, DeBeer BB, Bluett E, Teo AR, Morland LA, Heagerty PJ. Sequenced Treatment Effectiveness for Posttraumatic Stress (STEPS) Trial: A protocol for a pragmatic comparative effectiveness trial with baseline results. Contemp Clin Trials. 2024 Sep; 144:107606.
								Bilimoria KY, Haukoos JS, Doherty GM. Practical Guide to Pragmatic Clinical Trials in Surgical Education Research. JAMA Surg. 2024 May 01; 159(5):582-583.
								Shoji S, Kaltenbach LA, Granger BB, Fonarow GC, Al-Khalidi HR, Albert NM, Butler J, Allen LA, Felker GM, Harrison RW, Fudim M, Nelson AJ, Granger CB, Hernandez AF, Devore AD. Remote Follow-up in a Heart Failure Pragmatic Trial: Insights From the CONNECT-HF. J Card Fail. 2024 Nov; 30(11):1403-1410. | 
																	
																		
																			
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