 Interleukins
"Interleukins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types. They enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli.
| Descriptor ID |
D007378
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| MeSH Number(s) |
D12.644.276.374.465 D12.776.467.374.465 D23.529.374.465
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukins".
Below are MeSH descriptors whose meaning is more specific than "Interleukins".
This graph shows the total number of publications written about "Interleukins" by people in this website by year, and whether "Interleukins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 | | 1996 | 2 | 3 | 5 | | 1997 | 1 | 1 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 2 | 4 | | 2006 | 7 | 1 | 8 | | 2007 | 1 | 1 | 2 | | 2008 | 9 | 2 | 11 | | 2009 | 3 | 0 | 3 | | 2010 | 5 | 2 | 7 | | 2011 | 10 | 3 | 13 | | 2012 | 3 | 2 | 5 | | 2013 | 8 | 5 | 13 | | 2014 | 3 | 5 | 8 | | 2015 | 7 | 3 | 10 | | 2016 | 2 | 2 | 4 | | 2017 | 5 | 1 | 6 | | 2018 | 4 | 5 | 9 | | 2019 | 7 | 0 | 7 | | 2020 | 3 | 5 | 8 | | 2021 | 4 | 2 | 6 | | 2022 | 1 | 7 | 8 | | 2023 | 0 | 4 | 4 |
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Below are the most recent publications written about "Interleukins" by people in Profiles.
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Okurut S, Boulware DR, Okafor E, Rhein J, Kajumbula H, Bagaya BS, Bwanga F, Olobo JO, Manabe YC, Meya DB, Janoff EN. Divergent neuroimmune signatures in the cerebrospinal fluid predict differential gender-specific survival among patients with HIV-associated cryptococcal meningitis. Front Immunol. 2023; 14:1275443.
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Dinarello A, May M, Amo-Aparicio J, Azam T, Gaballa JM, Marchetti C, Tesoriere A, Ghirardo R, Redzic JS, Webber WS, Atif SM, Li S, Eisenmesser EZ, de Graaf DM, Dinarello CA. IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1? secretion. Proc Natl Acad Sci U S A. 2023 Nov 07; 120(45):e2306476120.
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Uzen R, Bayram F, Dursun H, Kardas F, Cakir M, Cucer N, Eken A, Donmez-Altuntas H. Characterization of peripheral blood T follicular helper (TFH) cells in patients with type 1 Gaucher disease and carriers. Blood Cells Mol Dis. 2023 05; 100:102728.
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Teufel LU, Netea MG, van de Veerdonk FL, Dinarello CA, Joosten LAB, Arts RJW. Opposing Effects of Interleukin-36? and Interleukin-38 on Trained Immunity. Int J Mol Sci. 2023 Jan 24; 24(3).
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de Graaf DM, Teufel LU, de Nooijer AH, van Gammeren AJ, Ermens AAM, Ga?l IO, Cri?an TO, van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Exploratory analysis of interleukin-38 in hospitalized COVID-19 patients. Immun Inflamm Dis. 2022 11; 10(11):e712.
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Sasaki T, Bracero S, Keegan J, Chen L, Cao Y, Stevens E, Qu Y, Wang G, Nguyen J, Sparks JA, Holers VM, Alves SE, Lederer JA, Costenbader KH, Rao DA. Longitudinal Immune Cell Profiling in Patients With Early Systemic Lupus Erythematosus. Arthritis Rheumatol. 2022 11; 74(11):1808-1821.
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Lonnemann N, Hosseini S, Ohm M, Geffers R, Hiller K, Dinarello CA, Korte M. IL-37 expression reduces acute and chronic neuroinflammation and rescues cognitive impairment in an Alzheimer's disease mouse model. Elife. 2022 08 30; 11.
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The E, de Graaf DM, Zhai Y, Yao Q, Ao L, Fullerton DA, Dinarello CA, Meng X. Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3. Proc Natl Acad Sci U S A. 2022 09 06; 119(36):e2202577119.
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Teufel LU, de Graaf DM, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Circulating interleukin-38 concentrations in healthy adults. Front Immunol. 2022; 13:964365.
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Brunt VE, Ikoba AP, Ziemba BP, Ballak DB, Hoischen A, Dinarello CA, Ehringer MA, Seals DR. Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs. Geroscience. 2023 02; 45(1):65-84.
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