 Interleukin-27
"Interleukin-27" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterodimeric cytokine composed of the IL-27p28 and EBI3 subunits. It is produced primarily by antigen-presenting cells after stimulation by microbial products or inflammatory mediators.
| Descriptor ID |
D064094
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| MeSH Number(s) |
D12.644.276.374.465.800 D12.776.467.374.465.800 D23.529.374.465.600
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| Concept/Terms |
Interleukin-27- Interleukin-27
- Interleukin 27
- IL-17D
- IL27
- IL-27
- Interleukin-17D
- Interleukin 17D
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Below are MeSH descriptors whose meaning is more general than "Interleukin-27".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-27".
This graph shows the total number of publications written about "Interleukin-27" by people in this website by year, and whether "Interleukin-27" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Interleukin-27" by people in Profiles.
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Suwanpradid J, Lee MJ, Hoang P, Kwock J, Floyd LP, Smith JS, Yin Z, Atwater AR, Rajagopal S, Kedl RM, Corcoran DL, Zhang JY, MacLeod AS. IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. Front Immunol. 2021; 12:713304.
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Klarquist J, Cross EW, Thompson SB, Willett B, Aldridge DL, Caffrey-Carr AK, Xu Z, Hunter CA, Getahun A, Kedl RM. B cells promote CD8 T?cell primary and memory responses to subunit vaccines. Cell Rep. 2021 08 24; 36(8):109591.
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Jacobs L, Berrens Z, Stenson EK, Zackoff M, Danziger-Isakov L, Lahni P, Wong HR. Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients. PLoS One. 2018; 13(11):e0207620.
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Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, Pinto-Plata VM, Criner GJ, Marchetti N, Bueno R, Agust? A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Par? PD, Levy RD, Rennard SI, Zhou X, Laird NM, Lin X, Beaty TH, Silverman EK, Cho MH. Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 07 01; 194(1):48-57.
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Yeruva L, Spencer NE, Saraf MK, Hennings L, Bowlin AK, Cleves MA, Mercer K, Chintapalli SV, Shankar K, Rank RG, Badger TM, Ronis MJ. Formula diet alters small intestine morphology, microbial abundance and reduces VE-cadherin and IL-10 expression in neonatal porcine model. BMC Gastroenterol. 2016 Mar 22; 16:40.
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Xie M, Mustovich AT, Jiang Y, Trudeau JB, Ray A, Ray P, Hu H, Holguin F, Freeman B, Wenzel SE. IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling. J Allergy Clin Immunol. 2015 Feb; 135(2):386-94.
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Desch AN, Gibbings SL, Clambey ET, Janssen WJ, Slansky JE, Kedl RM, Henson PM, Jakubzick C. Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction. Nat Commun. 2014 Aug 19; 5:4674.
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