Interleukin-23
"Interleukin-23" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa subunit that is shared with INTERLEUKIN-12. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells
Descriptor ID |
D053759
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MeSH Number(s) |
D12.644.276.374.465.759 D12.776.467.374.465.759 D23.529.374.465.550
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-23".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-23".
This graph shows the total number of publications written about "Interleukin-23" by people in this website by year, and whether "Interleukin-23" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 | 2008 | 1 | 1 | 2 | 2010 | 2 | 0 | 2 | 2011 | 2 | 0 | 2 | 2013 | 1 | 0 | 1 | 2014 | 2 | 0 | 2 | 2015 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 | 2019 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-23" by people in Profiles.
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Zehra Okus F, Busra Azizoglu Z, Canatan H, Eken A. S1P analogues SEW2871, BAF312 and FTY720 affect human Th17 and Treg generation ex vivo. Int Immunopharmacol. 2022 Jun; 107:108665.
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Ivanova DL, Mundhenke TM, Gigley JP. The IL-12- and IL-23-Dependent NK Cell Response Is Essential for Protective Immunity against Secondary Toxoplasma gondii Infection. J Immunol. 2019 12 01; 203(11):2944-2958.
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Gorman JA, Hundhausen C, Kinsman M, Arkatkar T, Allenspach EJ, Clough C, West SE, Thomas K, Eken A, Khim S, Hale M, Oukka M, Jackson SW, Cerosaletti K, Buckner JH, Rawlings DJ. The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets. Front Immunol. 2019; 10:44.
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Fujii U, Miyahara N, Taniguchi A, Waseda K, Morichika D, Kurimoto E, Koga H, Kataoka M, Gelfand EW, Cua DJ, Yoshimura A, Tanimoto M, Kanehiro A. IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema. Am J Respir Cell Mol Biol. 2016 11; 55(5):697-707.
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Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt Rde W, Tessier PA, Fuhlbrigge R, Rosenstiel P, Terhorst C, Murphy G, Geha RS. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016 09 19; 213(10):2147-66.
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Parlet CP, Kavanaugh JS, Horswill AR, Schlueter AJ. Chronic ethanol feeding increases the severity of Staphylococcus aureus skin infections by altering local host defenses. J Leukoc Biol. 2015 Apr; 97(4):769-78.
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Rendon JL, Li X, Brubaker AL, Kovacs EJ, Gamelli RL, Choudhry MA. The role of aryl hydrocarbon receptor in interleukin-23-dependent restoration of interleukin-22 following ethanol exposure and burn injury. Ann Surg. 2014 Mar; 259(3):582-90.
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Eken A, Singh AK, Oukka M. Interleukin 23 in Crohn's disease. Inflamm Bowel Dis. 2014 Mar; 20(3):587-95.
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Manuzak JA, Dillon SM, Lee EJ, Dong ZM, Hecht DK, Wilson CC. Increased Escherichia coli-induced interleukin-23 production by CD16+ monocytes correlates with systemic immune activation in untreated HIV-1-infected individuals. J Virol. 2013 Dec; 87(24):13252-62.
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Armstrong AW, Gelfand JM, Boehncke WH, Armstrong EJ. Cardiovascular comorbidities of psoriasis and psoriatic arthritis: a report from the GRAPPA 2012 annual meeting. J Rheumatol. 2013 Aug; 40(8):1434-7.
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