Interleukin-5
"Interleukin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.
Descriptor ID |
D015848
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MeSH Number(s) |
D12.644.276.374.465.202 D12.776.467.374.465.186 D23.529.374.465.202
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Concept/Terms |
Interleukin-5- Interleukin-5
- Interleukin 5
- BCGF-II
- Differentiation Factor, Eosinophil
- T-Cell-Replacing Factor
- T Cell Replacing Factor
- IL-5
- IL5
- T-Cell Replacing Factor
- Replacing Factor, T-Cell
- B-Cell Growth Factor-II
- B Cell Growth Factor II
- Eosinophil Differentiation Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-5".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-5".
This graph shows the total number of publications written about "Interleukin-5" by people in this website by year, and whether "Interleukin-5" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 | 1998 | 0 | 1 | 1 | 2001 | 0 | 2 | 2 | 2002 | 4 | 1 | 5 | 2003 | 0 | 1 | 1 | 2004 | 0 | 2 | 2 | 2006 | 1 | 0 | 1 | 2007 | 0 | 1 | 1 | 2008 | 1 | 1 | 2 | 2010 | 0 | 2 | 2 | 2012 | 1 | 1 | 2 | 2014 | 0 | 1 | 1 | 2016 | 1 | 1 | 2 | 2017 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 | 2020 | 0 | 2 | 2 | 2021 | 2 | 0 | 2 | 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Interleukin-5" by people in Profiles.
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Haruna NF, Politanska Y, Connelly AR, O'Connor K, Bhattacharya S, Miklaszewski GE, P?rez-Leonor XG, Rerko G, Hentenaar IT, Nguyen DC, Lamothe Molina PA, Bochner BS, Abdala-Valencia H, Gill MA, Lee FE, Berdnikovs S. scRNA-seq profiling of human granulocytes reveals expansion of developmentally flexible neutrophil precursors with mixed neutrophil and eosinophil properties in asthma. J Leukoc Biol. 2024 Nov 04; 116(5):1184-1197.
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Runnstrom MC, Lamothe PA, Faliti CE, Cheedarla N, Moreno A, Suthar MS, Nahata R, Ravindran M, Haddad NS, Morrison-Porter A, Quehl H, Ramonell RP, Woodruff M, Anam F, Zhang R, Swenson C, Polito C, Neveu W, Patel R, Smirnova N, Nguyen DC, Kim C, Hentenaar I, Kyu S, Usman S, Ngo T, Guo Z, Wu H, Daiss JL, Park J, Manning KE, Wali B, Ellis ML, Sharma S, Holguin F, Cheedarla S, Neish AS, Roback JD, Sanz I, Eun-Hyung Lee F. Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity. J Allergy Clin Immunol. 2024 Aug; 154(2):435-446.
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Guo Y, Mei Z, Li D, Banerjee A, Khalil MA, Burke A, Ritter J, Lau C, Kreisel D, Gelman AE, Jacobsen E, Luzina IG, Atamas SP, Krupnick AS. Ischemia reperfusion injury facilitates lung allograft acceptance through IL-33-mediated activation of donor-derived IL-5 producing group 2 innate lymphoid cells. Am J Transplant. 2022 08; 22(8):1963-1975.
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Coden ME, Walker MT, Jeong BM, Connelly AR, Nagasaka R, Berdnikovs S. Beyond Il-5: Metabolic Reprogramming and Stromal Support Are Prerequisite for Generation and Survival of Long-Lived Eosinophil. Cells. 2021 04 06; 10(4).
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Manka LA, Guntur VP, Denson JL, Dunn RM, Dollin YT, Strand MJ, Wechsler ME. Efficacy and safety of reslizumab in the treatment of eosinophilic granulomatosis with polyangiitis. Ann Allergy Asthma Immunol. 2021 06; 126(6):696-701.e1.
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Menzies-Gow A, Szefler SJ, Busse WW. The Relationship of Asthma Biologics to Remission for Asthma. J Allergy Clin Immunol Pract. 2021 03; 9(3):1090-1098.
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Coverstone AM, Seibold MA, Peters MC. Diagnosis and Management of T2-High Asthma. J Allergy Clin Immunol Pract. 2020 02; 8(2):442-450.
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Coden ME, Loffredo LF, Walker MT, Jeong BM, Nam K, Bochner BS, Abdala-Valencia H, Berdnikovs S. Fibrinogen Is a Specific Trigger for Cytolytic Eosinophil Degranulation. J Immunol. 2020 01 15; 204(2):438-448.
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McKay JT, Haro MA, Daly CA, Yammani RD, Pang B, Swords WE, Haas KM. PD-L2 Regulates B-1 Cell Antibody Production against Phosphorylcholine through an IL-5-Dependent Mechanism. J Immunol. 2017 09 15; 199(6):2020-2029.
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Johnston LK, Hsu CL, Krier-Burris RA, Chhiba KD, Chien KB, McKenzie A, Berdnikovs S, Bryce PJ. IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis. J Immunol. 2016 11 01; 197(9):3445-3453.
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