 Oncostatin M
"Oncostatin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
| Descriptor ID |
D053683
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| MeSH Number(s) |
D12.644.276.374.562 D12.776.467.374.562 D23.529.374.562
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oncostatin M".
Below are MeSH descriptors whose meaning is more specific than "Oncostatin M".
This graph shows the total number of publications written about "Oncostatin M" by people in this website by year, and whether "Oncostatin M" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Oncostatin M" by people in Profiles.
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Iijima H, Zhang F, Ambrosio F, Matsui Y. Network-based cytokine inference implicates Oncostatin M as a driver of an inflammation phenotype in knee osteoarthritis. Aging Cell. 2024 02; 23(2):e14043.
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Song K, Chen J, Ding J, Xu H, Xu H, Qin Z. Hyperbaric oxygen suppresses stemness-associated properties and Nanog and oncostatin M expression, but upregulates ?-catenin in orthotopic glioma models. J Int Med Res. 2020 Mar; 48(3):300060519872898.
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Ni K, Umair Mukhtar Mian M, Meador C, Gill A, Barwinska D, Cao D, Justice MJ, Jiang D, Schaefer N, Schweitzer KS, Chu HW, March KL, Petrache I. Oncostatin M and TNF-a Induce Alpha-1 Antitrypsin Production in Undifferentiated Adipose Stromal Cells. Stem Cells Dev. 2017 10 15; 26(20):1468-1476.
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Faffe DS, Flynt L, Mellema M, Moore PE, Silverman ES, Subramaniam V, Jones MR, Mizgerd JP, Whitehead T, Imrich A, Panettieri RA, Shore SA. Oncostatin M causes eotaxin-1 release from airway smooth muscle: synergy with IL-4 and IL-13. J Allergy Clin Immunol. 2005 Mar; 115(3):514-20.
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Gibbs P, Chen Q, Robinson WA. Effects of oncostatin M and tamoxifen on human melanoma cells. Melanoma Res. 1998 Jun; 8(3):221-6.
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Benigni F, Fantuzzi G, Sacco S, Sironi M, Pozzi P, Dinarello CA, Sipe JD, Poli V, Cappelletti M, Paonessa G, Pennica D, Panayotatos N, Ghezzi P. Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1. Blood. 1996 Mar 01; 87(5):1851-4.
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