Interleukin-33
"Interleukin-33" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the INTERLEUKIN-1 protein family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.
Descriptor ID |
D000067596
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MeSH Number(s) |
D12.644.276.374.465.850 D12.776.467.374.465.850 D23.529.374.465.850
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interleukin-33".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-33".
This graph shows the total number of publications written about "Interleukin-33" by people in this website by year, and whether "Interleukin-33" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2015 | 1 | 3 | 4 | 2016 | 1 | 1 | 2 | 2017 | 2 | 3 | 5 | 2018 | 0 | 2 | 2 | 2019 | 0 | 4 | 4 | 2020 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2022 | 1 | 0 | 1 | 2023 | 0 | 1 | 1 | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-33" by people in Profiles.
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Poole JA, England BR, Sayles H, Johnson TM, Duryee MJ, Hunter CD, Baker JF, Kerr GS, Kunkel G, Cannon GW, Sauer BC, Wysham KD, Joseph AM, Wallace BI, Thiele GM, Mikuls TR. Serum alarmins and the risk of incident interstitial lung disease in rheumatoid arthritis. Rheumatology (Oxford). 2024 Jul 01; 63(7):1998-2005.
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Gao J, Li Y, Guan X, Mohammed Z, Gomez G, Hui Y, Zhao D, Oskeritzian CA, Huang H. IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells. BMC Genomics. 2023 Oct 06; 24(1):592.
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Rao X, Hua F, Zhang L, Lin Y, Fang P, Chen S, Ying J, Wang X. Dual roles of interleukin-33 in cognitive function by regulating central nervous system inflammation. J Transl Med. 2022 08 16; 20(1):369.
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Guo Y, Mei Z, Li D, Banerjee A, Khalil MA, Burke A, Ritter J, Lau C, Kreisel D, Gelman AE, Jacobsen E, Luzina IG, Atamas SP, Krupnick AS. Ischemia reperfusion injury facilitates lung allograft acceptance through IL-33-mediated activation of donor-derived IL-5 producing group 2 innate lymphoid cells. Am J Transplant. 2022 08; 22(8):1963-1975.
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Schr?der A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M. IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33. Allergy. 2022 03; 77(3):856-869.
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Berman R, Kopf KW, Min E, Huang J, Downey GP, Alam R, Chu HW, Day BJ. IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice. Toxicol Appl Pharmacol. 2020 10 01; 404:115186.
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Rangarajan S, Thannickal VJ. Remember Me? The Bone Marrow in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019 10 15; 200(8):959-960.
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H?jen JF, Kristensen MLV, McKee AS, Wade MT, Azam T, Lunding LP, de Graaf DM, Swartzwelter BJ, Wegmann M, Tolstrup M, Beckman K, Fujita M, Fischer S, Dinarello CA. IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease. Nat Immunol. 2019 09; 20(9):1138-1149.
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Schaunaman N, Sanchez A, Dimasuay KG, Pavelka N, Numata M, Alam R, Martin RJ, Chu HW. Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation. Infect Immun. 2019 07; 87(7).
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Cho HS, Reboldi A, Hall JA, Berg LJ. The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine. Nat Commun. 2019 02 15; 10(1):784.
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