 Long Interspersed Nucleotide Elements
"Long Interspersed Nucleotide Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.
| Descriptor ID |
D020084
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| MeSH Number(s) |
G02.111.570.080.708.330.800.400 G05.360.080.708.330.800.400 G05.360.340.024.425.800.400
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| Concept/Terms |
Long Interspersed Nucleotide Elements- Long Interspersed Nucleotide Elements
- LINE Repeat Sequences
- LINE Repeat Sequence
- Repeat Sequence, LINE
- Repeat Sequences, LINE
- Sequence, LINE Repeat
- Sequences, LINE Repeat
- Long Interspersed DNA Sequence Elements
LINE-1 Elements- LINE-1 Elements
- Element, LINE-1
- Elements, LINE-1
- LINE 1 Elements
- LINE-1 Element
- L1 Elements
- Element, L1
- Elements, L1
- L1 Element
Jockey Elements- Jockey Elements
- Element, Jockey
- Elements, Jockey
- Jockey Element
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Below are MeSH descriptors whose meaning is more general than "Long Interspersed Nucleotide Elements".
Below are MeSH descriptors whose meaning is more specific than "Long Interspersed Nucleotide Elements".
This graph shows the total number of publications written about "Long Interspersed Nucleotide Elements" by people in this website by year, and whether "Long Interspersed Nucleotide Elements" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2012 | 2 | 0 | 2 | | 2013 | 2 | 0 | 2 | | 2014 | 1 | 1 | 2 | | 2016 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Long Interspersed Nucleotide Elements" by people in Profiles.
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Seplyarskiy VB, Soldatov RA, Koch E, McGinty RJ, Goldmann JM, Hernandez RD, Barnes K, Correa A, Burchard EG, Ellinor PT, McGarvey ST, Mitchell BD, Vasan RS, Redline S, Silverman E, Weiss ST, Arnett DK, Blangero J, Boerwinkle E, He J, Montgomery C, Rao DC, Rotter JI, Taylor KD, Brody JA, Chen YI, de las Fuentes L, Hwu CM, Rich SS, Manichaikul AW, Mychaleckyj JC, Palmer ND, Smith JA, Kardia SLR, Peyser PA, Bielak LF, O'Connor TD, Emery LS, Gilissen C, Wong WSW, Kharchenko PV, Sunyaev S. Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 Aug 27; 373(6558):1030-1035.
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Ivancevic AM, Kortschak RD, Bertozzi T, Adelson DL. Horizontal transfer of BovB and L1 retrotransposons in eukaryotes. Genome Biol. 2018 07 09; 19(1):85.
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Martin SL. On the move. Elife. 2018 02 21; 7.
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Ivancevic AM, Kortschak RD, Bertozzi T, Adelson DL. LINEs between Species: Evolutionary Dynamics of LINE-1 Retrotransposons across the Eukaryotic Tree of Life. Genome Biol Evol. 2016 12 14; 8(11):3301-3322.
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Meyer TJ, Held U, Nevonen KA, Klawitter S, Pirzer T, Carbone L, Schumann GG. The Flow of the Gibbon LAVA Element Is Facilitated by the LINE-1 Retrotransposition Machinery. Genome Biol Evol. 2016 10 30; 8(10):3209-3225.
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Criscione SW, Theodosakis N, Micevic G, Cornish TC, Burns KH, Neretti N, Rodic N. Genome-wide characterization of human L1 antisense promoter-driven transcripts. BMC Genomics. 2016 06 14; 17:463.
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Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A. A role for retrotransposon LINE-1 in fetal oocyte attrition in mice. Dev Cell. 2014 Jun 09; 29(5):521-533.
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White TE, Brandariz-Nu?ez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology. 2014 Jul; 460-461:34-44.
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Perng W, Villamor E, Shroff MR, Nettleton JA, Pilsner JR, Liu Y, Diez-Roux AV. Dietary intake, plasma homocysteine, and repetitive element DNA methylation in the Multi-Ethnic Study of Atherosclerosis (MESA). Nutr Metab Cardiovasc Dis. 2014 Jun; 24(6):614-22.
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Perng W, Mora-Plazas M, Mar?n C, Rozek LS, Baylin A, Villamor E. A prospective study of LINE-1DNA methylation and development of adiposity in school-age children. PLoS One. 2013; 8(4):e62587.
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