 Minichromosome Maintenance Proteins
"Minichromosome Maintenance Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability.
| Descriptor ID |
D064110
|
| MeSH Number(s) |
D08.811.277.040.025.159.186 D08.811.399.340.186 D12.776.167.409 D12.776.660.235.500 D12.776.664.235.750
|
| Concept/Terms |
MCM Protein Complex- MCM Protein Complex
- MCM2-7 Helicase
- Helicase, MCM2-7
- MCM2 7 Helicase
- MCM2-7 Complex
- MCM2 7 Complex
|
Below are MeSH descriptors whose meaning is more general than "Minichromosome Maintenance Proteins".
Below are MeSH descriptors whose meaning is more specific than "Minichromosome Maintenance Proteins".
This graph shows the total number of publications written about "Minichromosome Maintenance Proteins" by people in this website by year, and whether "Minichromosome Maintenance Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Minichromosome Maintenance Proteins" by people in Profiles.
-
Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, M?ndez J, Morrison CG, Passegu? E. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014 Aug 14; 512(7513):198-202.
-
Maiorano D, Cuvier O, Danis E, M?chali M. MCM8 is an MCM2-7-related protein that functions as a DNA helicase during replication elongation and not initiation. Cell. 2005 Feb 11; 120(3):315-28.
-
Sawyer SL, Cheng IH, Chai W, Tye BK. Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae. J Mol Biol. 2004 Jul 02; 340(2):195-202.
-
Homesley L, Lei M, Kawasaki Y, Sawyer S, Christensen T, Tye BK. Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins. Genes Dev. 2000 Apr 15; 14(8):913-26.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|