Telomeric Repeat Binding Protein 2
"Telomeric Repeat Binding Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the cell cycle. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues.
Descriptor ID |
D035341
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MeSH Number(s) |
D12.776.260.735.875 D12.776.660.235.700.875
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Telomeric Repeat Binding Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Telomeric Repeat Binding Protein 2".
This graph shows the total number of publications written about "Telomeric Repeat Binding Protein 2" by people in this website by year, and whether "Telomeric Repeat Binding Protein 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Telomeric Repeat Binding Protein 2" by people in Profiles.
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Mendez-Bermudez A, Lototska L, Pousse M, Tessier F, Croce O, Latrick CM, Cherdyntseva V, Nassour J, Xiaohua J, Lu Y, Abbadie C, Gagos S, Ye J, Gilson E. Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence. Nucleic Acids Res. 2022 07 22; 50(13):7493-7510.
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Lim CJ, Zaug AJ, Kim HJ, Cech TR. Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity. Nat Commun. 2017 10 20; 8(1):1075.
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Gaullier G, Miron S, Pisano S, Buisson R, Le Bihan YV, Tellier-Leb?gue C, Messaoud W, Roblin P, Guimar?es BG, Thai R, Giraud-Panis MJ, Gilson E, Le Du MH. A higher-order entity formed by the flexible assembly of RAP1 with TRF2. Nucleic Acids Res. 2016 Feb 29; 44(4):1962-76.
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Alder JK, Barkauskas CE, Limjunyawong N, Stanley SE, Kembou F, Tuder RM, Hogan BL, Mitzner W, Armanios M. Telomere dysfunction causes alveolar stem cell failure. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5099-104.
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Draskovic I, Arnoult N, Steiner V, Bacchetti S, Lomonte P, Londo?o-Vallejo A. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15726-31.
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