 Mucin-5B
"Mucin-5B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal components of high molecular weight salivary mucin.
| Descriptor ID |
D055257
|
| MeSH Number(s) |
D12.644.848.750 D12.776.395.560.631.207 D12.776.850.850
|
| Concept/Terms |
Mucin-5B- Mucin-5B
- Mucin 5B
- Mucin-5 Subtype B, Tracheobronchial
- Mucin 5 Subtype B, Tracheobronchial
- High Molecular Weight Salivary Mucin MG1
|
Below are MeSH descriptors whose meaning is more general than "Mucin-5B".
Below are MeSH descriptors whose meaning is more specific than "Mucin-5B".
This graph shows the total number of publications written about "Mucin-5B" by people in this website by year, and whether "Mucin-5B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 3 | 0 | 3 | | 2013 | 6 | 0 | 6 | | 2014 | 0 | 2 | 2 | | 2015 | 3 | 4 | 7 | | 2016 | 5 | 2 | 7 | | 2017 | 3 | 0 | 3 | | 2018 | 7 | 2 | 9 | | 2019 | 2 | 5 | 7 | | 2020 | 2 | 2 | 4 | | 2021 | 2 | 2 | 4 | | 2022 | 1 | 6 | 7 | | 2023 | 1 | 2 | 3 | | 2024 | 2 | 1 | 3 | | 2025 | 1 | 2 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Mucin-5B" by people in Profiles.
-
Wilson TM, Bolt M, Stahly A, Lee JS, Bang TJ, Sachs PB, Deane KD, Humphries SM, Solomon JJ, Demoruelle MK. Transforming growth factor-beta is increased in sputum from individuals with rheumatoid arthritis-associated pulmonary fibrosis. Rheumatology (Oxford). 2025 Jun 01; 64(6):3989-3995.
-
Hara N, Raclawska DS, Morgan LE, NeeDell JC, Dao L, Kato A, Jaramillo AM, Hume PS, Holguin F, Janssen WJ, Vladar EK, Evans CM. Requirement for Fucosyltransferase 2 in Allergic Airway Hyperreactivity and Mucus Obstruction. Am J Respir Cell Mol Biol. 2025 Apr; 72(4):408-417.
-
Blumhagen RZ, Humphries SM, Peljto AL, Lynch DA, Cardwell J, Bang TJ, Teague SD, Sigakis C, Walts AD, Puthenvedu D, Wolters PJ, Blackwell TS, Kropski JA, Brown KK, Schwarz MI, Yang IV, Steele MP, Schwartz DA, Lee JS. MUC5B Genotype and Other Common Variants Are Associated with Computational Imaging Features of Usual Interstitial Pneumonia. Ann Am Thorac Soc. 2025 Apr; 22(4):533-540.
-
Adegunsoye A, Kropski JA, Behr J, Blackwell TS, Corte TJ, Cottin V, Glanville AR, Glassberg MK, Griese M, Hunninghake GM, Johannson KA, Keane MP, Kim JS, Kolb M, Maher TM, Oldham JM, Podolanczuk AJ, Rosas IO, Martinez FJ, Noth I, Schwartz DA. Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):401-423.
-
Kurche JS, Cool CD, Blumhagen RZ, Dobrinskikh E, Heinz D, Herrera JA, Yang IV, Schwartz DA. MUC5B Idiopathic Pulmonary Fibrosis Risk Variant Promotes a Mucosecretory Phenotype and Loss of Small Airway Secretory Cells. Am J Respir Crit Care Med. 2024 Aug 15; 210(4):517-521.
-
Jaramillo AM, Vladar EK, Holguin F, Dickey BF, Evans CM. Emerging cell and molecular targets for treating mucus hypersecretion in asthma. Allergol Int. 2024 Jul; 73(3):375-381.
-
Moll M, Peljto AL, Kim JS, Xu H, Debban CL, Chen X, Menon A, Putman RK, Ghosh AJ, Saferali A, Nishino M, Hatabu H, Hobbs BD, Hecker J, McDermott G, Sparks JA, Wain LV, Allen RJ, Tobin MD, Raby BA, Chun S, Silverman EK, Zamora AC, Ortega VE, Garcia CK, Barr RG, Bleecker ER, Meyers DA, Kaner RJ, Rich SS, Manichaikul A, Rotter JI, Dupuis J, O'Connor GT, Fingerlin TE, Hunninghake GM, Schwartz DA, Cho MH. A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities. Am J Respir Crit Care Med. 2023 10 01; 208(7):791-801.
-
Ghosh AJ, Moll M, Hobbs BD, Cardwell J, Saferali A, Castaldi PJ, Cho MH, Silverman EK, Yang IV, Hersh CP. Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2023 05 15; 207(10):1401-1404.
-
Dobrinskikh E, Hennessy CE, Kurche JS, Kim E, Estrella AM, Cardwell J, Yang IV, Schwartz DA. Epithelial Endoplasmic Reticulum Stress Enhances the Risk of Muc5b-associated Lung Fibrosis. Am J Respir Cell Mol Biol. 2023 01; 68(1):62-74.
-
Borie R, Cardwell J, Konigsberg IR, Moore CM, Zhang W, Sasse SK, Gally F, Dobrinskikh E, Walts A, Powers J, Brancato J, Rojas M, Wolters PJ, Brown KK, Blackwell TS, Nakanishi T, Richards JB, Gerber AN, Fingerlin TE, Sachs N, Pulit SL, Zappala Z, Schwartz DA, Yang IV. Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2022 11 15; 206(10):1259-1270.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|