David Wyles
Concepts (239)
Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name |
Number of Publications
|
Most Recent Publication
|
Publications by All Authors
|
Concept Score
|
Why?
|
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Antiviral Agents | 58 | 2025 | 709 | 11.530 |
Why?
| Hepatitis C, Chronic | 31 | 2025 | 156 | 8.790 |
Why?
| Hepacivirus | 46 | 2024 | 237 | 7.910 |
Why?
| Hepatitis C | 27 | 2025 | 235 | 7.690 |
Why?
| Benzimidazoles | 16 | 2020 | 158 | 4.410 |
Why?
| Drug Resistance, Viral | 17 | 2018 | 110 | 3.310 |
Why?
| Coinfection | 15 | 2020 | 133 | 3.160 |
Why?
| HIV Infections | 28 | 2022 | 2744 | 3.140 |
Why?
| Ribavirin | 15 | 2020 | 92 | 2.430 |
Why?
| Sofosbuvir | 16 | 2022 | 57 | 2.360 |
Why?
| Quinoxalines | 7 | 2019 | 64 | 2.340 |
Why?
| Sulfonamides | 13 | 2020 | 494 | 2.330 |
Why?
| Fluorenes | 7 | 2020 | 39 | 2.320 |
Why?
| Liver Cirrhosis | 8 | 2020 | 278 | 2.270 |
Why?
| Viral Nonstructural Proteins | 9 | 2018 | 58 | 2.020 |
Why?
| Drug Therapy, Combination | 26 | 2020 | 1024 | 1.890 |
Why?
| Uridine Monophosphate | 5 | 2016 | 15 | 1.750 |
Why?
| Carbamates | 9 | 2020 | 45 | 1.520 |
Why?
| Anti-Retroviral Agents | 5 | 2019 | 230 | 1.490 |
Why?
| Protease Inhibitors | 10 | 2020 | 104 | 1.430 |
Why?
| Hepatitis B, Chronic | 3 | 2019 | 18 | 1.400 |
Why?
| Proline | 11 | 2020 | 79 | 1.300 |
Why?
| Pyrrolidines | 9 | 2019 | 65 | 1.250 |
Why?
| Congresses as Topic | 3 | 2021 | 217 | 1.220 |
Why?
| Hepatitis, Viral, Human | 3 | 2021 | 26 | 1.190 |
Why?
| Genotype | 19 | 2022 | 1836 | 1.020 |
Why?
| Cyclopropanes | 11 | 2020 | 88 | 1.010 |
Why?
| Drug Users | 2 | 2024 | 44 | 1.000 |
Why?
| Sustained Virologic Response | 10 | 2020 | 35 | 0.950 |
Why?
| Lactams, Macrocyclic | 10 | 2020 | 49 | 0.940 |
Why?
| Heterocyclic Compounds, 4 or More Rings | 3 | 2017 | 19 | 0.830 |
Why?
| HIV-1 | 8 | 2020 | 841 | 0.810 |
Why?
| Virus Replication | 7 | 2012 | 449 | 0.770 |
Why?
| Disease Eradication | 1 | 2020 | 4 | 0.720 |
Why?
| Organophosphonates | 4 | 2011 | 91 | 0.700 |
Why?
| Homosexuality, Male | 2 | 2021 | 180 | 0.700 |
Why?
| Anti-HIV Agents | 6 | 2020 | 744 | 0.680 |
Why?
| Humans | 75 | 2025 | 129705 | 0.670 |
Why?
| Valine | 7 | 2020 | 78 | 0.660 |
Why?
| Nucleic Acid Synthesis Inhibitors | 2 | 2015 | 16 | 0.570 |
Why?
| Imidazoles | 2 | 2015 | 224 | 0.560 |
Why?
| Ritonavir | 6 | 2020 | 73 | 0.550 |
Why?
| Darunavir | 1 | 2017 | 17 | 0.550 |
Why?
| Treatment Failure | 5 | 2019 | 347 | 0.540 |
Why?
| Aminoisobutyric Acids | 5 | 2019 | 7 | 0.540 |
Why?
| Uracil | 5 | 2020 | 29 | 0.520 |
Why?
| Treatment Outcome | 18 | 2023 | 10299 | 0.510 |
Why?
| Leucine | 5 | 2019 | 106 | 0.510 |
Why?
| Antiretroviral Therapy, Highly Active | 3 | 2015 | 269 | 0.510 |
Why?
| Anilides | 5 | 2020 | 72 | 0.500 |
Why?
| Middle Aged | 30 | 2025 | 31103 | 0.500 |
Why?
| Education, Medical, Continuing | 1 | 2016 | 126 | 0.480 |
Why?
| Male | 39 | 2025 | 63544 | 0.480 |
Why?
| Biomedical Research | 1 | 2021 | 656 | 0.470 |
Why?
| Adenine | 4 | 2020 | 247 | 0.460 |
Why?
| RNA, Viral | 7 | 2015 | 622 | 0.460 |
Why?
| Oligopeptides | 2 | 2013 | 256 | 0.450 |
Why?
| Pyridazines | 1 | 2014 | 48 | 0.450 |
Why?
| Viral Load | 7 | 2020 | 449 | 0.450 |
Why?
| 2-Naphthylamine | 5 | 2020 | 7 | 0.440 |
Why?
| Macrocyclic Compounds | 3 | 2019 | 10 | 0.430 |
Why?
| Adult | 29 | 2025 | 35595 | 0.420 |
Why?
| Female | 37 | 2025 | 68561 | 0.420 |
Why?
| Purines | 1 | 2014 | 170 | 0.420 |
Why?
| Quinolines | 1 | 2014 | 149 | 0.420 |
Why?
| Replicon | 3 | 2009 | 14 | 0.410 |
Why?
| Liver | 1 | 2021 | 1848 | 0.400 |
Why?
| Disease Management | 1 | 2016 | 596 | 0.390 |
Why?
| Scavenger Receptors, Class B | 1 | 2012 | 10 | 0.390 |
Why?
| Aged | 17 | 2024 | 22113 | 0.370 |
Why?
| Retreatment | 2 | 2021 | 69 | 0.350 |
Why?
| Drug Synergism | 3 | 2008 | 354 | 0.340 |
Why?
| Acquired Immunodeficiency Syndrome | 2 | 2020 | 227 | 0.310 |
Why?
| Dideoxynucleosides | 2 | 2005 | 20 | 0.300 |
Why?
| Liver Diseases | 2 | 2016 | 290 | 0.300 |
Why?
| Interferon-alpha | 4 | 2013 | 191 | 0.290 |
Why?
| Cytokines | 1 | 2015 | 2008 | 0.280 |
Why?
| Amino Acid Substitution | 2 | 2018 | 281 | 0.270 |
Why?
| Global Health | 2 | 2020 | 333 | 0.270 |
Why?
| Cytosine | 2 | 2009 | 46 | 0.270 |
Why?
| Hepatitis B virus | 2 | 2019 | 35 | 0.240 |
Why?
| Mass Screening | 3 | 2023 | 1130 | 0.240 |
Why?
| HIV | 2 | 2019 | 224 | 0.240 |
Why?
| Herpes Simplex | 1 | 2005 | 94 | 0.230 |
Why?
| Hepatitis | 1 | 2004 | 49 | 0.230 |
Why?
| Alanine | 2 | 2021 | 134 | 0.220 |
Why?
| Prevalence | 3 | 2019 | 2557 | 0.210 |
Why?
| Interferons | 2 | 2015 | 187 | 0.210 |
Why?
| Young Adult | 10 | 2019 | 12363 | 0.200 |
Why?
| Hospitals | 2 | 2024 | 635 | 0.200 |
Why?
| Mutation, Missense | 3 | 2014 | 319 | 0.200 |
Why?
| Interferon beta-1a | 1 | 2021 | 12 | 0.190 |
Why?
| Hepatitis A | 1 | 2021 | 26 | 0.180 |
Why?
| Adenosine Monophosphate | 1 | 2021 | 62 | 0.180 |
Why?
| Tenofovir | 2 | 2020 | 225 | 0.180 |
Why?
| Hepatitis B | 1 | 2021 | 61 | 0.180 |
Why?
| World Health Organization | 1 | 2020 | 109 | 0.170 |
Why?
| Disease Progression | 2 | 2019 | 2612 | 0.170 |
Why?
| Data Interpretation, Statistical | 2 | 2018 | 338 | 0.170 |
Why?
| Polyethylene Glycols | 2 | 2015 | 598 | 0.160 |
Why?
| United States | 10 | 2025 | 14078 | 0.160 |
Why?
| Ribosomes | 2 | 2010 | 162 | 0.150 |
Why?
| Esters | 2 | 2009 | 74 | 0.150 |
Why?
| CD4 Lymphocyte Count | 2 | 2017 | 269 | 0.150 |
Why?
| Immunologic Factors | 1 | 2020 | 230 | 0.150 |
Why?
| Nucleic Acid Conformation | 4 | 2014 | 706 | 0.140 |
Why?
| Hospitalization | 2 | 2024 | 2091 | 0.140 |
Why?
| Alanine Transaminase | 1 | 2018 | 149 | 0.140 |
Why?
| DNA, Viral | 1 | 2019 | 381 | 0.140 |
Why?
| Genes, Viral | 1 | 2016 | 94 | 0.140 |
Why?
| DNA Mutational Analysis | 1 | 2018 | 391 | 0.130 |
Why?
| Mutation | 2 | 2018 | 3674 | 0.130 |
Why?
| Molecular Structure | 2 | 2008 | 469 | 0.130 |
Why?
| High-Throughput Nucleotide Sequencing | 2 | 2016 | 484 | 0.130 |
Why?
| Patient Compliance | 1 | 2020 | 566 | 0.130 |
Why?
| Survival Analysis | 1 | 2019 | 1297 | 0.130 |
Why?
| Adolescent | 5 | 2022 | 20355 | 0.130 |
Why?
| Dose-Response Relationship, Drug | 2 | 2017 | 1969 | 0.120 |
Why?
| Regulatory Sequences, Ribonucleic Acid | 1 | 2014 | 19 | 0.120 |
Why?
| Opiate Substitution Treatment | 1 | 2016 | 140 | 0.120 |
Why?
| AIDS-Related Opportunistic Infections | 1 | 2015 | 126 | 0.120 |
Why?
| Chemokines | 1 | 2015 | 230 | 0.110 |
Why?
| Chemokine CXCL10 | 1 | 2014 | 33 | 0.110 |
Why?
| Drug Interactions | 1 | 2015 | 371 | 0.110 |
Why?
| Phenylenediamines | 1 | 2013 | 9 | 0.110 |
Why?
| Viral Proteins | 2 | 2014 | 330 | 0.110 |
Why?
| Fibrosis | 1 | 2016 | 521 | 0.110 |
Why?
| Prognosis | 2 | 2019 | 3801 | 0.110 |
Why?
| Quality of Life | 1 | 2025 | 2712 | 0.100 |
Why?
| Microbial Sensitivity Tests | 2 | 2012 | 351 | 0.100 |
Why?
| Drug Combinations | 3 | 2019 | 327 | 0.100 |
Why?
| Drug Discovery | 1 | 2013 | 131 | 0.100 |
Why?
| Administration, Oral | 1 | 2014 | 790 | 0.100 |
Why?
| Mental Disorders | 1 | 2020 | 1025 | 0.090 |
Why?
| Cohort Studies | 5 | 2024 | 5410 | 0.090 |
Why?
| Case-Control Studies | 2 | 2017 | 3363 | 0.090 |
Why?
| Telemedicine | 1 | 2020 | 792 | 0.090 |
Why?
| Models, Molecular | 3 | 2012 | 1480 | 0.090 |
Why?
| Drug-Related Side Effects and Adverse Reactions | 1 | 2013 | 259 | 0.090 |
Why?
| Prodrugs | 1 | 2011 | 49 | 0.090 |
Why?
| Nucleosides | 1 | 2010 | 25 | 0.090 |
Why?
| Japan | 2 | 2021 | 102 | 0.090 |
Why?
| Riboswitch | 1 | 2012 | 68 | 0.090 |
Why?
| Cell Line, Tumor | 2 | 2008 | 3106 | 0.080 |
Why?
| Prospective Studies | 4 | 2023 | 7130 | 0.080 |
Why?
| Drug Administration Schedule | 3 | 2017 | 763 | 0.080 |
Why?
| Risk Assessment | 1 | 2019 | 3297 | 0.080 |
Why?
| Drug Design | 1 | 2010 | 157 | 0.080 |
Why?
| Biomarkers | 1 | 2020 | 3893 | 0.080 |
Why?
| Cell Line | 2 | 2012 | 2768 | 0.080 |
Why?
| Piperidines | 1 | 2010 | 186 | 0.080 |
Why?
| Body Mass Index | 1 | 2017 | 2246 | 0.080 |
Why?
| Phenylthiourea | 1 | 2008 | 5 | 0.080 |
Why?
| Practice Guidelines as Topic | 1 | 2016 | 1529 | 0.080 |
Why?
| Immunity, Innate | 1 | 2014 | 806 | 0.070 |
Why?
| Plasmids | 1 | 2009 | 359 | 0.070 |
Why?
| Structure-Activity Relationship | 1 | 2009 | 539 | 0.070 |
Why?
| Inhibitory Concentration 50 | 1 | 2006 | 83 | 0.070 |
Why?
| Luciferases | 1 | 2006 | 148 | 0.070 |
Why?
| Genes, Reporter | 1 | 2006 | 269 | 0.060 |
Why?
| Thailand | 1 | 2025 | 16 | 0.060 |
Why?
| Saquinavir | 1 | 2004 | 1 | 0.060 |
Why?
| Indinavir | 1 | 2004 | 7 | 0.060 |
Why?
| Simplexvirus | 1 | 2005 | 83 | 0.060 |
Why?
| Nelfinavir | 1 | 2004 | 8 | 0.060 |
Why?
| Drug Labeling | 1 | 2005 | 42 | 0.060 |
Why?
| Uganda | 1 | 2025 | 80 | 0.060 |
Why?
| Brazil | 1 | 2025 | 102 | 0.060 |
Why?
| Nevirapine | 1 | 2004 | 16 | 0.060 |
Why?
| Oxazines | 1 | 2004 | 26 | 0.060 |
Why?
| Pandemics | 2 | 2024 | 1526 | 0.060 |
Why?
| Benzoxazines | 1 | 2004 | 31 | 0.060 |
Why?
| Lopinavir | 1 | 2004 | 31 | 0.060 |
Why?
| Alkynes | 1 | 2004 | 53 | 0.060 |
Why?
| Zidovudine | 1 | 2004 | 78 | 0.060 |
Why?
| Time Factors | 1 | 2015 | 6593 | 0.060 |
Why?
| Pregnancy | 1 | 2017 | 6273 | 0.060 |
Why?
| Liver Function Tests | 1 | 2004 | 116 | 0.060 |
Why?
| Reverse Transcriptase Inhibitors | 1 | 2004 | 82 | 0.060 |
Why?
| Transfection | 1 | 2006 | 904 | 0.060 |
Why?
| Carcinoma, Hepatocellular | 1 | 2006 | 267 | 0.060 |
Why?
| South Africa | 1 | 2025 | 199 | 0.060 |
Why?
| Bone Marrow Transplantation | 1 | 2005 | 267 | 0.060 |
Why?
| Pyrimidinones | 1 | 2004 | 102 | 0.060 |
Why?
| Recombinant Fusion Proteins | 1 | 2006 | 640 | 0.060 |
Why?
| Double-Blind Method | 2 | 2021 | 1871 | 0.050 |
Why?
| Polyphosphates | 1 | 2022 | 36 | 0.050 |
Why?
| Republic of Korea | 1 | 2021 | 28 | 0.050 |
Why?
| Singapore | 1 | 2021 | 20 | 0.050 |
Why?
| Dried Blood Spot Testing | 1 | 2022 | 84 | 0.050 |
Why?
| Liver Neoplasms | 1 | 2006 | 637 | 0.050 |
Why?
| Retrospective Studies | 5 | 2019 | 14669 | 0.050 |
Why?
| Mexico | 1 | 2021 | 188 | 0.050 |
Why?
| Protein Biosynthesis | 2 | 2014 | 409 | 0.050 |
Why?
| Emergency Service, Hospital | 2 | 2023 | 2044 | 0.050 |
Why?
| Raltegravir Potassium | 1 | 2019 | 17 | 0.040 |
Why?
| Intensive Care Units | 1 | 2024 | 738 | 0.040 |
Why?
| Clinical Trials, Phase II as Topic | 1 | 2019 | 73 | 0.040 |
Why?
| Clinical Trials, Phase III as Topic | 1 | 2019 | 91 | 0.040 |
Why?
| Drug Resistance, Multiple, Viral | 1 | 2017 | 11 | 0.040 |
Why?
| Longitudinal Studies | 1 | 2024 | 2670 | 0.030 |
Why?
| Kinetics | 1 | 2020 | 1620 | 0.030 |
Why?
| Oxygen | 1 | 2021 | 921 | 0.030 |
Why?
| Medicaid | 1 | 2020 | 447 | 0.030 |
Why?
| Program Evaluation | 1 | 2020 | 880 | 0.030 |
Why?
| Incidence | 2 | 2013 | 2658 | 0.030 |
Why?
| RNA | 1 | 2022 | 877 | 0.030 |
Why?
| Cell-Free System | 1 | 2014 | 48 | 0.030 |
Why?
| Hepatitis C Antibodies | 1 | 2014 | 10 | 0.030 |
Why?
| Spain | 1 | 2014 | 38 | 0.030 |
Why?
| Enzyme-Linked Immunosorbent Assay | 1 | 2016 | 828 | 0.030 |
Why?
| Polymorphism, Genetic | 1 | 2017 | 643 | 0.030 |
Why?
| Aged, 80 and over | 2 | 2019 | 7074 | 0.030 |
Why?
| Patient Acceptance of Health Care | 1 | 2020 | 776 | 0.030 |
Why?
| Patient Reported Outcome Measures | 1 | 2017 | 359 | 0.030 |
Why?
| Risk Factors | 2 | 2020 | 9832 | 0.030 |
Why?
| Withholding Treatment | 1 | 2013 | 69 | 0.030 |
Why?
| Patient Care | 1 | 2014 | 110 | 0.030 |
Why?
| Early Diagnosis | 1 | 2014 | 235 | 0.030 |
Why?
| Plasma | 1 | 2014 | 206 | 0.030 |
Why?
| Fluorescence Resonance Energy Transfer | 1 | 2012 | 175 | 0.020 |
Why?
| Virus Internalization | 1 | 2010 | 43 | 0.020 |
Why?
| Ligands | 1 | 2012 | 615 | 0.020 |
Why?
| Pilot Projects | 1 | 2015 | 1567 | 0.020 |
Why?
| Recombinant Proteins | 1 | 2013 | 1306 | 0.020 |
Why?
| Magnesium | 1 | 2009 | 152 | 0.020 |
Why?
| Lamivudine | 1 | 2009 | 61 | 0.020 |
Why?
| Genome, Viral | 1 | 2009 | 131 | 0.020 |
Why?
| Referral and Consultation | 1 | 2014 | 731 | 0.020 |
Why?
| Logistic Models | 1 | 2013 | 1980 | 0.020 |
Why?
| Phenotype | 1 | 2014 | 3063 | 0.020 |
Why?
| Base Sequence | 1 | 2009 | 2161 | 0.020 |
Why?
| Severity of Illness Index | 1 | 2013 | 2783 | 0.020 |
Why?
| Randomized Controlled Trials as Topic | 1 | 2011 | 1379 | 0.010 |
Why?
| Mice, Transgenic | 1 | 2009 | 2075 | 0.010 |
Why?
| Animals | 2 | 2018 | 34733 | 0.010 |
Why?
| Substance-Related Disorders | 1 | 2011 | 1023 | 0.010 |
Why?
| Signal Transduction | 1 | 2009 | 4863 | 0.010 |
Why?
| Mice | 1 | 2009 | 16585 | 0.010 |
Why?
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