 CCAAT-Enhancer-Binding Protein-alpha
"CCAAT-Enhancer-Binding Protein-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CCAAT-enhancer-binding protein found in LIVER; ADIPOSE TISSUE; INTESTINES; LUNG; ADRENAL GLANDS; PLACENTA; OVARY and peripheral blood mononuclear cells (LEUKOCYTES, MONONUCLEAR). Experiments with knock-out mice have demonstrated that CCAAT-enhancer binding protein-alpha is essential for the functioning and differentiation of HEPATOCYTES and ADIPOCYTES.
| Descriptor ID |
D022763
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| MeSH Number(s) |
D12.776.260.108.124.500 D12.776.660.167.500 D12.776.930.127.124.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Protein-alpha".
Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Protein-alpha".
This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Protein-alpha" by people in this website by year, and whether "CCAAT-Enhancer-Binding Protein-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2000 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "CCAAT-Enhancer-Binding Protein-alpha" by people in Profiles.
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Petruk S, Mariani SA, De Dominici M, Porazzi P, Minieri V, Cai J, Iacovitti L, Flomenberg N, Calabretta B, Mazo A. Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification. Cell Rep. 2017 04 11; 19(2):295-306.
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Qiao L, Guo Z, Bosco C, Guidotti S, Wang Y, Wang M, Parast M, Schaack J, Hay WW, Moore TR, Shao J. Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice. Diabetes. 2015 Sep; 64(9):3111-20.
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Fleenor CJ, Rozhok AI, Zaberezhnyy V, Mathew D, Kim J, Tan AC, Bernstein ID, DeGregori J. Contrasting roles for C/EBPa and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects. Stem Cells. 2015 Apr; 33(4):1345-58.
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Qi X, Hong J, Chaves L, Zhuang Y, Chen Y, Wang D, Chabon J, Graham B, Ohmori K, Li Y, Huang H. Antagonistic regulation by the transcription factors C/EBPa and MITF specifies basophil and mast cell fates. Immunity. 2013 Jul 25; 39(1):97-110.
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Gutman JA, Hoffner B. A novel CCAAT/enhancer binding protein a germline variant in a case of acute myeloid leukemia. Leuk Lymphoma. 2012 May; 53(5):1006-7.
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Yang G, Hinson MD, Bordner JE, Lin QS, Fernando AP, La P, Wright CJ, Dennery PA. Silencing hyperoxia-induced C/EBPa in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011 Aug; 301(2):L187-96.
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Qi X, Nishida J, Chaves L, Ohmori K, Huang H. CCAAT/enhancer-binding protein alpha (C/EBPalpha) is critical for interleukin-4 expression in response to FcepsilonRI receptor cross-linking. J Biol Chem. 2011 May 06; 286(18):16063-73.
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Bristol JA, Morrison TE, Kenney SC. CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter. Mol Immunol. 2009 Aug; 46(13):2706-13.
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Qiao L, Zou C, Shao P, Schaack J, Johnson PF, Shao J. Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha. J Biol Chem. 2008 Apr 04; 283(14):8788-95.
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Fox KE, Fankell DM, Erickson PF, Majka SM, Crossno JT, Klemm DJ. Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2. J Biol Chem. 2006 Dec 29; 281(52):40341-53.
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