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Aaron M Johnson

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-BioChem&Molecular Genetics

    Collapse Research 
    Collapse research activities and funding
    R21CA270573     (JOHNSON, AARON M.)May 1, 2023 - Apr 30, 2025
    NIH
    Disrupting long noncoding RNA methylation to elicit antimorph behavior in breast cancer
    Role: Principal Investigator
    R35GM119575     (JOHNSON, AARON M.)Aug 16, 2016 - May 31, 2021
    NIH
    Mechanisms of heterochromatin targeting and epigenetic genome regulation
    Role: Principal Investigator
    R00GM094291     (JOHNSON, AARON M.)Sep 1, 2010 - Jan 31, 2016
    NIH
    Comprehensive Characterization of Heterochromatin Domains
    Role: Principal Investigator
    K99GM094291     (JOHNSON, AARON M.)Sep 1, 2010 - Aug 31, 2012
    NIH
    Comprehensive Characterization of Heterochromatin Domains
    Role: Principal Investigator
    F32GM078799     (JOHNSON, AARON M.)Sep 1, 2006 - Aug 31, 2009
    NIH
    Mechanistic Studies of silent chromatin spreading
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Johnson A, Wu R, Peetz M, Gygi SP, Moazed D. Heterochromatic gene silencing by activator interference and a transcription elongation barrier. J Biol Chem. 2013 Oct 04; 288(40):28771-82. PMID: 23940036.
      View in: PubMed
    2. Wang F, Li G, Altaf M, Lu C, Currie MA, Johnson A, Moazed D. Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):8495-500. PMID: 23650358.
      View in: PubMed
    3. Johnson A, Li G, Sikorski TW, Buratowski S, Woodcock CL, Moazed D. Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell. 2009 Sep 24; 35(6):769-81. PMID: 19782027.
      View in: PubMed
    4. Sinha M, Watanabe S, Johnson A, Moazed D, Peterson CL. Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling. Cell. 2009 Sep 18; 138(6):1109-21. PMID: 19766565.
      View in: PubMed
    5. Laurence TA, Kwon Y, Johnson A, Hollars CW, O'Donnell M, Camarero JA, Barsky D. Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopy. J Biol Chem. 2008 Aug 22; 283(34):22895-906. PMID: 18556658.
      View in: PubMed
    6. McInerney P, Johnson A, Katz F, O'Donnell M. Characterization of a triple DNA polymerase replisome. Mol Cell. 2007 Aug 17; 27(4):527-38. PMID: 17707226.
      View in: PubMed
    7. Johnson A, Yao NY, Bowman GD, Kuriyan J, O'Donnell M. The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. J Biol Chem. 2006 Nov 17; 281(46):35531-43. PMID: 16980295.
      View in: PubMed
    8. Yao NY, Johnson A, Bowman GD, Kuriyan J, O'Donnell M. Mechanism of proliferating cell nuclear antigen clamp opening by replication factor C. J Biol Chem. 2006 Jun 23; 281(25):17528-17539. PMID: 16608854.
      View in: PubMed
    9. Johnson A, O'Donnell M. DNA ligase: getting a grip to seal the deal. Curr Biol. 2005 Feb 08; 15(3):R90-2. PMID: 15694297.
      View in: PubMed
    10. Johnson A, O'Donnell M. Cellular DNA replicases: components and dynamics at the replication fork. Annu Rev Biochem. 2005; 74:283-315. PMID: 15952889.
      View in: PubMed
    11. Goedken ER, Levitus M, Johnson A, Bustamante C, O'Donnell M, Kuriyan J. Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding. J Mol Biol. 2004 Mar 05; 336(5):1047-59. PMID: 15037068.
      View in: PubMed
    12. Snyder AK, Williams CR, Johnson A, O'Donnell M, Bloom LB. Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: II. Uncoupling the beta and DNA binding activities of the gamma complex. J Biol Chem. 2004 Feb 06; 279(6):4386-93. PMID: 14610068.
      View in: PubMed
    13. Johnson A, O'Donnell M. Ordered ATP hydrolysis in the gamma complex clamp loader AAA+ machine. J Biol Chem. 2003 Apr 18; 278(16):14406-13. PMID: 12582167.
      View in: PubMed
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