 Interleukin-18
"Interleukin-18" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine which resembles IL-1 structurally and IL-12 functionally. It enhances the cytotoxic activity of NK CELLS and CYTOTOXIC T-LYMPHOCYTES, and appears to play a role both as neuroimmunomodulator and in the induction of mucosal immunity.
| Descriptor ID |
D020382
|
| MeSH Number(s) |
D12.644.276.374.465.518 D12.776.467.374.465.518 D23.529.374.465.518
|
| Concept/Terms |
Interleukin-18- Interleukin-18
- Interleukin 18
- IFN-gamma-Inducing Factor
- IL-18
- Interferon-gamma Inducing Factor
- Inducing Factor, Interferon-gamma
- Interferon gamma Inducing Factor
- Interferon-gamma-Inducing Factor
- IFN-gamma Inducing Factor
- IFN gamma Inducing Factor
- Inducing Factor, IFN-gamma
- IL18
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-18".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-18".
This graph shows the total number of publications written about "Interleukin-18" by people in this website by year, and whether "Interleukin-18" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 3 | 4 | 7 | | 1999 | 6 | 0 | 6 | | 2000 | 10 | 1 | 11 | | 2001 | 13 | 4 | 17 | | 2002 | 14 | 3 | 17 | | 2003 | 11 | 2 | 13 | | 2004 | 5 | 2 | 7 | | 2005 | 5 | 4 | 9 | | 2006 | 8 | 3 | 11 | | 2007 | 5 | 0 | 5 | | 2008 | 3 | 2 | 5 | | 2009 | 5 | 2 | 7 | | 2010 | 3 | 0 | 3 | | 2011 | 3 | 5 | 8 | | 2012 | 3 | 4 | 7 | | 2013 | 5 | 7 | 12 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 1 | 3 | | 2016 | 3 | 1 | 4 | | 2017 | 1 | 1 | 2 | | 2018 | 2 | 2 | 4 | | 2019 | 0 | 2 | 2 | | 2020 | 2 | 3 | 5 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 1 | 1 | | 2024 | 1 | 3 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Interleukin-18" by people in Profiles.
-
Kaneko S, Shimbo A, Irabu H, Mizuta M, Nakagishi Y, Iwata N, Yokoyama K, Yasumura J, Akamine K, Ueno K, Fujita S, Watanabe K, Watanabe S, Nishikawa H, Fujimura J, Mori M, Shimizu M. Serum interleukin-18 levels can improve the diagnostic performance of the PRINTO and ILAR criteria for systemic juvenile idiopathic arthritis. Cytokine. 2024 Oct; 182:156719.
-
Jiang L, Lunding LP, Webber WS, Beckmann K, Azam T, Falkesgaard H?jen J, Amo-Aparicio J, Dinarello A, Nguyen TT, Pessara U, Parera D, Orlicky DJ, Fischer S, Wegmann M, Dinarello CA, Li S. An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation. Front Immunol. 2024; 15:1427100.
-
Turner MJ, Rumpel JA, Spray BJ, Stence N, Neuberger I, Frymoyer A, Chock VY, Courtney S, Gist K. Urine biomarkers of acute kidney injury and association with brain MRI abnormalities in neonatal hypoxic-ischemic encephalopathy. J Perinatol. 2024 Aug; 44(8):1203-1207.
-
Edrosolan KA, Shlipak MG, Scherzer R, Estrella MM, Gustafson D, Karim R, Fisher M, Cohen M, Kassaye S, Dumond J, Abraham A, McCulloch CE, Ascher SB. Mediation analysis of chronic kidney disease risk factors using kidney biomarkers in women living with HIV. AIDS. 2024 05 01; 38(6):813-824.
-
Johnson MJ, Tommerdahl KL, Vinovskis C, Waikar S, Reinicke T, Parikh CR, Obeid W, Nelson RG, van Raalte DH, Pyle L, Nadeau KJ, Bjornstad P. Relationship between biomarkers of tubular injury and intrarenal hemodynamic dysfunction in youth with type 1 diabetes. Pediatr Nephrol. 2022 12; 37(12):3085-3092.
-
Rumpel J, Spray BJ, Chock VY, Kirkley MJ, Slagle CL, Frymoyer A, Cho SH, Gist KM, Blaszak R, Poindexter B, Courtney SE. Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia. J Pediatr. 2022 02; 241:133-140.e3.
-
Li S, Jiang L, Beckmann K, H?jen JF, Pessara U, Powers NE, de Graaf DM, Azam T, Lindenberger J, Eisenmesser EZ, Fischer S, Dinarello CA. A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling. J Biol Chem. 2021 Jan-Jun; 296:100630.
-
Mizuta M, Shimizu M, Irabu H, Usami M, Inoue N, Nakagishi Y, Wada T, Yachie A. Comparison of serum cytokine profiles in macrophage activation syndrome complicating different background rheumatic diseases in children. Rheumatology (Oxford). 2021 01 05; 60(1):231-238.
-
Gruber CN, Patel RS, Trachtman R, Lepow L, Amanat F, Krammer F, Wilson KM, Onel K, Geanon D, Tuballes K, Patel M, Mouskas K, O'Donnell T, Merritt E, Simons NW, Barcessat V, Del Valle DM, Udondem S, Kang G, Gangadharan S, Ofori-Amanfo G, Laserson U, Rahman A, Kim-Schulze S, Charney AW, Gnjatic S, Gelb BD, Merad M, Bogunovic D. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020 11 12; 183(4):982-995.e14.
-
Chui H, Caldwell J, Yordanova M, Cockovski V, Fredric D, Harel-Sterling M, Haasz M, Al-Ismaili Z, Pizzi M, Ma Q, Devarajan P, Goldstein SL, Zappitelli M. Tubular injury and cell-cycle arrest biomarkers?to predict acute kidney injury in noncritically ill children receiving aminoglycosides. Biomark Med. 2020 Jul; 14(10):879-894.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|