 LIM-Homeodomain Proteins
"LIM-Homeodomain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of LIM domain proteins that include an additional centrally-located homeodomain region that binds AT-rich sites on DNA. Many LIM-homeodomain proteins play a role as transcriptional regulators that direct cell fate.
| Descriptor ID |
D060850
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| MeSH Number(s) |
D12.776.260.529 D12.776.512.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "LIM-Homeodomain Proteins".
Below are MeSH descriptors whose meaning is more specific than "LIM-Homeodomain Proteins".
This graph shows the total number of publications written about "LIM-Homeodomain Proteins" by people in this website by year, and whether "LIM-Homeodomain Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2010 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "LIM-Homeodomain Proteins" by people in Profiles.
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Wade AK, Liu Y, Bethea MM, Toren E, Tse HM, Hunter CS. LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet ß-cell function. J Biol Chem. 2019 08 02; 294(31):11728-11740.
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Fregoso SP, Dwyer BE, Franco SJ. Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer. Development. 2019 03 07; 146(5).
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Moreno RL, Williams K, Jones KL, Ribera AB. Investigation of Islet2a function in zebrafish embryos: Mutants and morphants differ in morphologic phenotypes and gene expression. PLoS One. 2018; 13(6):e0199233.
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Ching ST, Infante CR, Du W, Sharir A, Park S, Menke DB, Klein OD. Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a. Hum Mol Genet. 2018 01 01; 27(1):107-119.
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Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, Li C, Sander M, Stein R, Sussel L, Won KJ, May CL, Stoffers DA. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ß cells. J Clin Invest. 2017 01 03; 127(1):215-229.
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Gross S, Garofalo DC, Balderes DA, Mastracci TL, Dias JM, Perlmann T, Ericson J, Sussel L. The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2. Development. 2016 07 15; 143(14):2616-28.
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Li Q, Barish S, Okuwa S, Maciejewski A, Brandt AT, Reinhold D, Jones CD, Volkan PC. A Functionally Conserved Gene Regulatory Network Module Governing Olfactory Neuron Diversity. PLoS Genet. 2016 Jan; 12(1):e1005780.
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Moreno RL, Ribera AB. Spinal neurons require Islet1 for subtype-specific differentiation of electrical excitability. Neural Dev. 2014 Aug 22; 9:19.
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Olesnicky E, Hernandez-Lagunas L, Artinger KB. prdm1a Regulates sox10 and islet1 in the development of neural crest and Rohon-Beard sensory neurons. Genesis. 2010 Nov; 48(11):656-66.
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Jackman WR, Draper BW, Stock DW. Fgf signaling is required for zebrafish tooth development. Dev Biol. 2004 Oct 01; 274(1):139-57.
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