DNA Methylation
"DNA Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
Descriptor ID |
D019175
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MeSH Number(s) |
G02.111.035.538.161 G02.111.218 G03.059.538.161 G05.206
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Concept/Terms |
DNA Methylation- DNA Methylation
- DNA Methylations
- Methylation, DNA
- Methylations, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Methylation".
Below are MeSH descriptors whose meaning is more specific than "DNA Methylation".
This graph shows the total number of publications written about "DNA Methylation" by people in this website by year, and whether "DNA Methylation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1998 | 0 | 2 | 2 | 1999 | 1 | 2 | 3 | 2000 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 3 | 1 | 4 | 2004 | 1 | 0 | 1 | 2005 | 2 | 2 | 4 | 2006 | 2 | 3 | 5 | 2007 | 1 | 3 | 4 | 2008 | 5 | 9 | 14 | 2009 | 2 | 7 | 9 | 2010 | 4 | 6 | 10 | 2011 | 5 | 10 | 15 | 2012 | 8 | 7 | 15 | 2013 | 8 | 4 | 12 | 2014 | 4 | 11 | 15 | 2015 | 18 | 7 | 25 | 2016 | 10 | 10 | 20 | 2017 | 13 | 13 | 26 | 2018 | 12 | 9 | 21 | 2019 | 14 | 11 | 25 | 2020 | 14 | 10 | 24 | 2021 | 9 | 12 | 21 | 2022 | 3 | 15 | 18 | 2023 | 11 | 8 | 19 | 2024 | 19 | 6 | 25 | 2025 | 6 | 2 | 8 |
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Below are the most recent publications written about "DNA Methylation" by people in Profiles.
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Goyne C, Fair AE, Yilmaz D, Race J, Schuette A, Caillier SJ, Aaen GS, Abrams AW, Benson LA, Casper TC, Chitnis T, Gorman MP, Lotze TE, Krupp LB, Mar SS, Ness JM, Rensel M, Rodriguez M, Rose JW, Schreiner TL, Tillema JM, Waldman AT, Wheeler YS, Barcellos LF, Waubant E, Graves JS. Epigenetic Aging in Pediatric-Onset Multiple Sclerosis. Neurology. 2025 Jun 24; 104(12):e213673.
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Kirmani S, Huan T, Van Amburg JC, Joehanes R, Uddin MM, Nguyen NQH, Yu B, Brody JA, Fornage M, Bressler J, Sotoodehnia N, Ong DA, Puddu F, Floyd JS, Ballantyne CM, Psaty BM, Raffield LM, Natarajan P, Conneely KN, Weinstock JS, Carson AP, Lange LA, Ferrier K, Heard-Costa NL, Murabito J, Bick AG, Levy D. Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation. Nat Commun. 2025 May 20; 16(1):4678.
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Young KA, Hosseini M, Mistry JJ, Morganti C, Mills TS, Cai X, James BT, Nye GJ, Fournier NR, Voisin V, Chegini A, Schimmer AD, Bader GD, Egan G, Mansour MR, Challen GA, Pietras EM, Fisher-Wellman KH, Ito K, Chan SM, Trowbridge JJ. Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis. Nat Commun. 2025 Apr 16; 16(1):3306.
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Neumann A, Sammallahti S, Cosin-Tomas M, Reese SE, Suderman M, Alemany S, Almqvist C, Andrusaityte S, Arshad SH, Bakermans-Kranenburg MJ, Beilin L, Breton C, Bustamante M, Czamara D, Dabelea D, Eng C, Eskenazi B, Fuemmeler BF, Gilliland FD, Grazuleviciene R, H?berg SE, Herberth G, Holland N, Hough A, Hu D, Huen K, H?ls A, Jarvelin MR, Jin J, Julvez J, Koletzko BV, Koppelman GH, Kull I, Lu X, Maitre L, Mason D, Mel?n E, Merid SK, Molloy PL, Mori TA, Mulder RH, Page CM, Richmond RC, R?der S, Ross JP, Schellhas L, Sebert S, Sheppard D, Snieder H, Starling AP, Stein DJ, Tindula G, van IJzendoorn MH, Vonk J, Walton E, Witonsky J, Xu CJ, Yang IV, Yousefi PD, Zar HJ, Zenclussen AC, Zhang H, Tiemeier H, London SJ, Felix JF, Cecil C. Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium. Genome Med. 2025 Apr 14; 17(1):39.
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Li Y, Jones K, Ober C, Starling AP, Gower WA, Bacharier LB, Chandran A, Dabelea DM, Fry RC, Gold DR, Hansen KD, Herbstman JB, Hivert MF, Keet C, Miller RL, Jacobson LP, Ladd-Acosta C. Newborn blood DNA methylation and childhood asthma: findings from the ECHO program. Int J Epidemiol. 2025 Apr 12; 54(3).
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Chalkley ML, Guerin LN, Iyer T, Mallahan S, Nelson S, Sahin M, Hodges E, Ess KC, Ihrie RA. Human TSC2 mutant cells exhibit aberrations in early neurodevelopment accompanied by changes in the DNA Methylome. Hum Mol Genet. 2025 Apr 06; 34(8):684-698.
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Hu Y, Haessler J, Lundin JI, Darst BF, Whitsel EA, Grove M, Guan W, Xia R, Szeto M, Raffield LM, Ratliff S, Wang Y, Wang X, Fohner AE, Lynch MT, Patel YM, Lani Park S, Xu H, Mitchell BD, Bis JC, Sotoodehnia N, Brody JA, Psaty BM, Peloso GM, Tsai MY, Rich SS, Rotter JI, Smith JA, Kardia SLR, Reiner AP, Lange L, Fornage M, Pankow JS, Graff M, North KE, Kooperberg C, Peters U. Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants. Clin Epigenetics. 2025 Apr 02; 17(1):54.
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Gorashi RM, Baddour T, Chittle SJ, F?lix V?lez NE, Wenning MA, Anseth KS, Mestroni L, Pe?a B, Guo P, Aguado BA. Y chromosome-linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues. Sci Adv. 2025 Mar 14; 11(11):eads5717.
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Malik F, Koo SC, Din NU, Tran QT, Lopez-Nunez O, Barresi S, Vallese S, Milano G, Miele E, Clay MR, Alaggio R, Orr BA. Reappraisal of soft tissue myoepithelial tumors by DNA methylation profiling reveals an epigenetically distinct group of mostly fusion-driven neoplasms. Virchows Arch. 2025 Mar; 486(3):573-584.
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Guest EM, Kairalla JA, Devidas M, Hibbitts E, Carroll AJ, Heerema NA, Kubaney HR, August MA, Ramesh S, Yoo B, Farooqi MS, Pauly MG, Wechsler DS, Miles RR, Reid JM, Kihei CD, Gore L, Raetz EA, Hunger SP, Loh ML, Brown PA. Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children's Oncology Group trial AALL15P1. Haematologica. 2024 Dec 01; 109(12):3918-3927.
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