 Proteolysis
"Proteolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cleavage of proteins into smaller peptides or amino acids either by PROTEASES or non-enzymatically (e.g., Hydrolysis). It does not include Protein Processing, Post-Translational.
| Descriptor ID |
D059748
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| MeSH Number(s) |
G02.111.720 G03.812
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| Concept/Terms |
Proteolysis- Proteolysis
- Proteolyses
- Protein Degradation
- Degradation, Protein
- Degradations, Protein
- Protein Degradations
Protein Digestion- Protein Digestion
- Digestion, Protein
- Digestions, Protein
- Protein Digestions
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Below are MeSH descriptors whose meaning is more general than "Proteolysis".
Below are MeSH descriptors whose meaning is more specific than "Proteolysis".
This graph shows the total number of publications written about "Proteolysis" by people in this website by year, and whether "Proteolysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 | | 2012 | 4 | 14 | 18 | | 2013 | 2 | 7 | 9 | | 2014 | 0 | 7 | 7 | | 2015 | 2 | 8 | 10 | | 2016 | 0 | 6 | 6 | | 2017 | 3 | 16 | 19 | | 2018 | 2 | 7 | 9 | | 2019 | 2 | 6 | 8 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proteolysis" by people in Profiles.
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Thomas T, Stefanoni D, Reisz JA, Nemkov T, Bertolone L, Francis RO, Hudson KE, Zimring JC, Hansen KC, Hod EA, Spitalnik SL, D'Alessandro A. COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight. 2020 07 23; 5(14).
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Morton AB, Norton CE, Jacobsen NL, Fernando CA, Cornelison DDW, Segal SS. Barium chloride injures myofibers through calcium-induced proteolysis with fragmentation of motor nerves and microvessels. Skelet Muscle. 2019 11 06; 9(1):27.
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Antonia AL, Gibbs KD, Trahair ED, Pittman KJ, Martin AT, Schott BH, Smith JS, Rajagopal S, Thompson JW, Reinhardt RL, Ko DC. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Front Cell Infect Microbiol. 2019; 9:280.
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Gulbranson DR, Crisman L, Lee M, Ouyang Y, Menasche BL, Demmitt BA, Wan C, Nomura T, Ye Y, Yu H, Shen J. AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis. Dev Cell. 2019 08 19; 50(4):436-446.e5.
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Langan RA, Boyken SE, Ng AH, Samson JA, Dods G, Westbrook AM, Nguyen TH, Lajoie MJ, Chen Z, Berger S, Mulligan VK, Dueber JE, Novak WRP, El-Samad H, Baker D. De novo design of bioactive protein switches. Nature. 2019 08; 572(7768):205-210.
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Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. TRIM5a Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019 06 11; 27(11):3269-3283.e6.
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Nahar A, Fu X, Polovin G, Orth JD, Park S. Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases. J Biol Chem. 2019 04 19; 294(16):6562-6577.
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Guerrero-Gómez D, Mora-Lorca JA, Sáenz-Narciso B, Naranjo-Galindo FJ, Muñoz-Lobato F, Parrado-Fernández C, Goikolea J, Cedazo-Minguez Á, Link CD, Neri C, Sequedo MD, Vázquez-Manrique RP, Fernández-Suárez E, Goder V, Pané R, Cabiscol E, Askjaer P, Cabello J, Miranda-Vizuete A. Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation. Cell Death Differ. 2019 09; 26(9):1545-1565.
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Huang L, Li L, Tien C, LaBarbera DV, Chen C. Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment. Sci Rep. 2019 01 22; 9(1):301.
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Guo A, Wang Y, Chen B, Wang Y, Yuan J, Zhang L, Hall D, Wu J, Shi Y, Zhu Q, Chen C, Thiel WH, Zhan X, Weiss RM, Zhan F, Musselman CA, Pufall M, Zhu W, Au KF, Hong J, Anderson ME, Grueter CE, Song LS. E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator. Science. 2018 12 21; 362(6421).
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