 Nucleotidyltransferases
"Nucleotidyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.
| Descriptor ID |
D009713
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| MeSH Number(s) |
D08.811.913.696.445
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleotidyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Nucleotidyltransferases".
This graph shows the total number of publications written about "Nucleotidyltransferases" by people in this website by year, and whether "Nucleotidyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 3 | 0 | 3 | | 2019 | 2 | 2 | 4 | | 2020 | 0 | 1 | 1 | | 2021 | 2 | 0 | 2 | | 2023 | 1 | 2 | 3 | | 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleotidyltransferases" by people in Profiles.
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Tak U, Schinkel K, Walth P, Tay JW, Hartwick EW, Whiteley AT. Bacterial 2',3'-cGAMP activates a SAVED effector to form membrane-disrupting filaments and restrict phage replication. Cell Host Microbe. 2026 Apr 08; 34(4):720-733.e7.
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Rohilla A, Singh AK, Koleske B, Srikrishna G, Bishai WR. Structure-based virtual screening and in vitro validation of inhibitors of cyclic dinucleotide phosphodiesterases ENPP1 and CdnP. Microbiol Spectr. 2024 01 11; 12(1):e0201223.
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Barbour AT, Wuttke DS. RPA-like single-stranded DNA-binding protein complexes including CST serve as specialized processivity factors for polymerases. Curr Opin Struct Biol. 2023 08; 81:102611.
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Ledvina HE, Ye Q, Gu Y, Sullivan AE, Quan Y, Lau RK, Zhou H, Corbett KD, Whiteley AT. An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature. 2023 04; 616(7956):319-325.
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Song K, Wu Y, Fu B, Wang L, Hao W, Hua F, Sun Y, Dorf ME, Li S. Leaked Mitochondrial C1QBP Inhibits Activation of the DNA Sensor cGAS. J Immunol. 2021 10 15; 207(8):2155-2166.
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Govande AA, Duncan-Lowey B, Eaglesham JB, Whiteley AT, Kranzusch PJ. Molecular basis of CD-NTase nucleotide selection in CBASS anti-phage defense. Cell Rep. 2021 06 01; 35(9):109206.
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Hemphill WO, Simpson SR, Liu M, Salsbury FR, Hollis T, Grayson JM, Perrino FW. TREX1 as a Novel Immunotherapeutic Target. Front Immunol. 2021; 12:660184.
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Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection. Cell. 2020 07 09; 182(1):38-49.e17.
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Simpson SR, Rego SL, Harvey SE, Liu M, Hemphill WO, Venkatadri R, Sharma R, Grayson JM, Perrino FW. T Cells Produce IFN-a in the TREX1 D18N Model of Lupus-like Autoimmunity. J Immunol. 2020 01 15; 204(2):348-359.
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Zhou W, Whiteley AT, Kranzusch PJ. Analysis of human cGAS activity and structure. Methods Enzymol. 2019; 625:13-40.
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