 Transcriptional Elongation Factors
"Transcriptional Elongation Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcription factors whose primary function is to regulate the rate in which RNA is transcribed.
| Descriptor ID |
D035602
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| MeSH Number(s) |
D12.776.930.955
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcriptional Elongation Factors".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Elongation Factors".
This graph shows the total number of publications written about "Transcriptional Elongation Factors" by people in this website by year, and whether "Transcriptional Elongation Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 | | 2006 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcriptional Elongation Factors" by people in Profiles.
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Leydon AR, Downing B, Solano Sanchez J, Loll-Krippleber R, Belliveau NM, Rodriguez-Mias RA, Bauer AJ, Watson IJ, Bae L, Vill?n J, Brown GW, Nemhauser JL. A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex. J Cell Biol. 2025 Feb 03; 224(2).
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Fong N, Sheridan RM, Ramachandran S, Bentley DL. The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model. Mol Cell. 2022 10 06; 82(19):3632-3645.e4.
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Ma XR, Xu L, Xu S, Klein BJ, Wang H, Das S, Li K, Yang KS, Sohail S, Chapman A, Kutateladze TG, Shi X, Liu WR, Wen H. Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain. J Med Chem. 2021 08 12; 64(15):10997-11013.
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Decker TM. Mechanisms of Transcription Elongation Factor DSIF (Spt4-Spt5). J Mol Biol. 2021 07 09; 433(14):166657.
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Dahl NA, Danis E, Balakrishnan I, Wang D, Pierce A, Walker FM, Gilani A, Serkova NJ, Madhavan K, Fosmire S, Green AL, Foreman NK, Venkataraman S, Vibhakar R. Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma. Cell Rep. 2020 04 07; 31(1):107485.
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Cortazar MA, Sheridan RM, Erickson B, Fong N, Glover-Cutter K, Brannan K, Bentley DL. Control of RNA Pol II Speed by PNUTS-PP1 and Spt5 Dephosphorylation Facilitates Termination by a "Sitting Duck Torpedo" Mechanism. Mol Cell. 2019 12 19; 76(6):896-908.e4.
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Sheridan RM, Fong N, D'Alessandro A, Bentley DL. Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5' Pause Release, Termination, and Transcription Elongation Rate. Mol Cell. 2019 01 03; 73(1):107-118.e4.
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Li S, Almeida AR, Radebaugh CA, Zhang L, Chen X, Huang L, Thurston AK, Kalashnikova AA, Hansen JC, Luger K, Stargell LA. The elongation factor Spn1 is a multi-functional chromatin binding protein. Nucleic Acids Res. 2018 03 16; 46(5):2321-2334.
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Tencer AH, Gatchalian J, Klein BJ, Khan A, Zhang Y, Strahl BD, van Wely KHM, Kutateladze TG. A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO. Structure. 2017 10 03; 25(10):1530-1539.e3.
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Sen R, Kaja A, Ferdoush J, Lahudkar S, Barman P, Bhaumik SR. An mRNA Capping Enzyme Targets FACT to the Active Gene To Enhance the Engagement of RNA Polymerase II into Transcriptional Elongation. Mol Cell Biol. 2017 07 01; 37(13).
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