 Lactoferrin
"Lactoferrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.
| Descriptor ID |
D007781
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| MeSH Number(s) |
D08.811.277.656.300.760.471 D08.811.277.656.959.350.471 D12.776.157.427.750.249 D12.776.256.626.816.500.507 D12.776.377.457.507 D12.776.395.507 D12.776.556.579.750.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactoferrin".
Below are MeSH descriptors whose meaning is more specific than "Lactoferrin".
This graph shows the total number of publications written about "Lactoferrin" by people in this website by year, and whether "Lactoferrin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lactoferrin" by people in Profiles.
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Vergara D, L?pez O, Bustamante M, Shene C. An in vitro digestion study of encapsulated lactoferrin in rapeseed phospholipid-based liposomes. Food Chem. 2020 Aug 15; 321:126717.
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Mika A, Gaffney M, Roller R, Hills A, Bouchet CA, Hulen KA, Thompson RS, Chichlowski M, Berg BM, Fleshner M. Feeding the developing brain: Juvenile rats fed diet rich in prebiotics and bioactive milk fractions exhibit reduced anxiety-related behavior and modified gene expression in emotion circuits. Neurosci Lett. 2018 06 11; 677:103-109.
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Alhalwani AY, Repine JE, Knowles MK, Huffman JA. Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure. Anal Bioanal Chem. 2018 Feb; 410(4):1389-1396.
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MacManus CF, Collins CB, Nguyen TT, Alfano RW, Jedlicka P, de Zoeten EF. VEN-120, a Recombinant Human Lactoferrin, Promotes a Regulatory T Cell [Treg] Phenotype and Drives Resolution of Inflammation in Distinct Murine Models of Inflammatory Bowel Disease. J Crohns Colitis. 2017 Sep 01; 11(9):1101-1112.
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Mika A, Day HE, Martinez A, Rumian NL, Greenwood BN, Chichlowski M, Berg BM, Fleshner M. Early life diets with prebiotics and bioactive milk fractions attenuate the impact of stress on learned helplessness behaviours and alter gene expression within neural circuits important for stress resistance. Eur J Neurosci. 2017 02; 45(3):342-357.
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Wu Q, Jiang D, Minor MN, Martin RJ, Chu HW. In vivo function of airway epithelial TLR2 in host defense against bacterial infection. Am J Physiol Lung Cell Mol Physiol. 2011 Apr; 300(4):L579-86.
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Yin H, Cheng L, Holt M, Hail N, Maclaren R, Ju C. Lactoferrin protects against acetaminophen-induced liver injury in mice. Hepatology. 2010 Mar; 51(3):1007-16.
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Yin H, Cheng L, Agarwal C, Agarwal R, Ju C. Lactoferrin protects against concanavalin A-induced liver injury in mice. Liver Int. 2010 Apr; 30(4):623-32.
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Sagel SD, Sontag MK, Accurso FJ. Relationship between antimicrobial proteins and airway inflammation and infection in cystic fibrosis. Pediatr Pulmonol. 2009 Apr; 44(4):402-9.
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Walker TR, Land ML, Kartashov A, Saslowsky TM, Lyerly DM, Boone JH, Rufo PA. Fecal lactoferrin is a sensitive and specific marker of disease activity in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2007 Apr; 44(4):414-22.
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